Uniting GDF15 and GFRAL: Therapeutic Opportunities in Obesity and Beyond von Mullican, Shannon E., Rangwala, Shamina M.

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GFRAL is the receptor for GDF15 and the ligand promotes weight loss in mice and nonhuman primates von Mullican, Shannon E, Lin-Schmidt, Xiefan, Chin, Chen-Ni, Chavez, Jose A, Furman, Jennifer L, Armstrong, Anthony A, Beck, Stephen C, South, Victoria J, Dinh, Thai Q, Cash-Mason, Tanesha D, Cavanaugh, Cassandre R, Nelson, Serena, Huang, Chichi, Hunter, Michael J, Rangwala, Shamina M

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HIF-independent regulation of VEGF and angiogenesis by the transcriptional coactivator PGC-1α von Arany, Zoltan, Foo, Shi-Yin, Ma, Yanhong, Ruas, Jorge L., Bommi-Reddy, Archana, Girnun, Geoffrey, Cooper, Marcus, Laznik, Dina, Chinsomboon, Jessica, Rangwala, Shamina M., Baek, Kwan Hyuck, Rosenzweig, Anthony, Spiegelman, Bruce M.

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Estrogen-related Receptor γ Is a Key Regulator of Muscle Mitochondrial Activity and Oxidative Capacity von Rangwala, Shamina M., Wang, Xiaomei, Calvo, Jennifer A., Lindsley, Loren, Zhang, Yunyu, Deyneko, Galina, Beaulieu, Valerie, Gao, Jiaping, Turner, Gordon, Markovits, Judit

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A Long-Acting PYY 3-36 Analog Mediates Robust Anorectic Efficacy with Minimal Emesis in Nonhuman Primates von Rangwala, Shamina M, D'Aquino, Katharine, Zhang, Yue-Mei, Bader, Lindsay, Edwards, Wilson, Zheng, Songmao, Eckardt, Annette, Lacombe, Ann, Pick, Rebecca, Moreno, Veronica, Kang, Lijuan, Jian, Wenying, Arnoult, Eric, Case, Martin, Jenkinson, Celia, Chi, Ellen, Swanson, Ronald V, Kievit, Paul, Grove, Kevin, Macielag, Mark, Erion, Mark D, SinhaRoy, Ranabir, Leonard, James N

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Peroxisome proliferator-activated receptor γ in diabetes and metabolism von Rangwala, Shamina M, Lazar, Mitchell A

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A Long-Acting PYY3–36 Analog Mediates Robust Anorectic Efficacy with Minimal Emesis in Nonhuman Primates von Rangwala, Shamina M., D’Aquino, Katharine, Zhang, Yue-Mei, Bader, Lindsay, Edwards, Wilson, Zheng, Songmao, Eckardt, Annette, Lacombe, Ann, Pick, Rebecca, Moreno, Veronica, Kang, Lijuan, Jian, Wenying, Arnoult, Eric, Case, Martin, Jenkinson, Celia, Chi, Ellen, Swanson, Ronald V., Kievit, Paul, Grove, Kevin, Macielag, Mark, Erion, Mark D., SinhaRoy, Ranabir, Leonard, James N.

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Muscle-specific expression of PPARγ coactivator-1α improves exercise performance and increases peak oxygen uptake von CALVO, Jennifer A, DANIELS, Thomas G, XIAOMEI WANG, PAUL, Angelika, JIANDIE LIN, SPIEGELMAN, Bruce M, STEVENSON, Susan C, RANGWALA, Shamina M

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Regulation of Fasted Blood Glucose by Resistin von Banerjee, Ronadip R., Rangwala, Shamina M., Shapiro, Jennifer S., Rich, A. Sophie, Rhoades, Ben, Qi, Yong, Wang, Juan, Rajala, Michael W., Pocai, Alessandro, Scherer, Phillipp E., Steppan, Claire M., Ahima, Rexford S., Obici, Silvana, Rossetti, Luciano, Lazar, Mitchell A.

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Design, synthesis and preclinical evaluation of bio-conjugated amylinomimetic peptides as long-acting amylin receptor agonists von Patch, Raymond J., Zhang, Rui, Edavettal, Suzanne, Macielag, Mark J., Eckardt, Annette J., Li, Jiali, Rives, Marie-Laure, Edwards, Wilson, Hinke, Simon A., Qiu, Xi, Jian, Wenying, Libiger, Ondrej, Zheng, Songmao, Jeyaseelan, Jey, Liang, Yin, Rangwala, Shamina M., Leonard, James N., Hornby, Pamela

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Abnormal Glucose Homeostasis due to Chronic Hyperresistinemia von RANGWALA, Shamina M, RICH, A. Sophie, RHOADES, Ben, SHAPIRO, Jennifer S, OBICI, Silvana, ROSSETTI, Luciano, LAZAR, Mitchell A

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Estrogen-related receptor α is essential for the expression of antioxidant protection genes and mitochondrial function von Rangwala, Shamina M., Li, Xiaoyan, Lindsley, Loren, Wang, Xiaomei, Shaughnessy, Stacey, Daniels, Thomas G., Szustakowski, Joseph, Nirmala, N.R., Wu, Zhidan, Stevenson, Susan C.

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Interdomain communication regulating ligand binding by PPAR-γ von Shao, Dalei, Rangwala, Shamina M., Bailey, Shannon T., Krakow, Samuel L., Reginato, Mauricio J., Lazar, Mitchell A.

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Transcriptional control of adipogenesis von RANGWALA, S. M, LAZAR, M. A

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Thiazolidinedione activation of peroxisome proliferator-activated receptor gamma can enhance mitochondrial potential and promote cell survival von Wang, Y Lynn, Frauwirth, Kenneth A, Rangwala, Shamina M, Lazar, Mitchell A, Thompson, Craig B

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Activation of peroxisome proliferator-activated receptor isoforms and inhibition of prostaglandin H2 synthases by ibuprofen, naproxen, and indomethacin von JARADAT, Maisa S, WONGSUD, Buanus, PHORNCHIRASILP, Srichan, RANGWALA, Shamina M, SHAMS, Gamal, SUTTON, Melissa, ROMSTEDT, Karl J, NOONAN, Daniel J, FELLER, Dennis R

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A novel therapy for colitis utilizing PPAR-gamma ligands to inhibit the epithelial inflammatory response von Su, C G, Wen, X, Bailey, S T, Jiang, W, Rangwala, S M, Keilbaugh, S A, Flanigan, A, Murthy, S, Lazar, M A, Wu, G D

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Genetic Modulation of PPARγ Phosphorylation Regulates Insulin Sensitivity von Rangwala, Shamina M., Rhoades, Ben, Shapiro, Jennifer S., Rich, A.Sophie, Kim, Jason K., Shulman, Gerald I., Kaestner, Klaus H., Lazar, Mitchell A.

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Growth Differentiation Factor-15 (GDF-15) Inhibits Gastric Emptying in Rodents as Part of Its Anorectic Mechanism of Action von HINKE, SIMON A., CAVANAUGH, CASSANDRE R., KIRCHNER, THOMAS, LANG, WENSHENG, MENG, RONG, WALLACE, NATHANIEL H., LIU, JR. JIANYING, D'AQUINO, KATHARINE E., HO, GEORGE, RANKIN, MATTHEW M., WANG, SHENG-PING, CHAVEZ, JOSE A., NELSON, SERENA M., FURMAN, JENNIFER, MULLICAN, SHANNON, RANGWALA, SHAMINA M., NAWROCKI, ANDREA R.

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MON-LB020 Compound H Causes a Sustained Reduction in Food Intake and Body Weight in Obese Cynomolgus von Hinke, Simon, Zheng, Songmao, Wang, Yuanping, Brian, Geist, Fei, Chen, Peggy, Wong, Katharine, D’Aquino, Stojanvic-Susulic, Vedrana, Rangwala, Shamina, Nawrocki, Andrea

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