Statistical power and significance testing in large-scale genetic studies von Sham, Pak C., Purcell, Shaun M.

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GATES: A Rapid and Powerful Gene-Based Association Test Using Extended Simes Procedure von Li, Miao-Xin, Gui, Hong-Sheng, Kwan, Johnny S.H., Sham, Pak C.

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Evaluating the effective numbers of independent tests and significant p-value thresholds in commercial genotyping arrays and public imputation reference datasets von Li, Miao-Xin, Yeung, Juilian M. Y., Cherny, Stacey S., Sham, Pak C.

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PLINK: A Tool Set for Whole-Genome Association and Population-Based Linkage Analyses von Purcell, Shaun, Neale, Benjamin, Todd-Brown, Kathe, Thomas, Lori, Ferreira, Manuel A.R., Bender, David, Maller, Julian, Sklar, Pamela, de Bakker, Paul I.W., Daly, Mark J., Sham, Pak C.

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Meta-analysis shows significant association between dopamine system genes and attention deficit hyperactivity disorder (ADHD) von DAWEI LI, SHAM, Pak C, OWEN, Michael J, LIN HE

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A comprehensive framework for prioritizing variants in exome sequencing studies of Mendelian diseases von Li, Miao-Xin, Gui, Hong-Sheng, Kwan, Johnny S H, Bao, Su-Ying, Sham, Pak C

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The Future of Association Studies: Gene-Based Analysis and Replication von Neale, Benjamin M., Sham, Pak C.

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MTMR4 SNVs modulate ion channel degradation and clinical severity in congenital long QT syndrome: insights in the mechanism of action of protective modifier genes von Lee, Yee-Ki, Sala, Luca, Mura, Manuela, Rocchetti, Marcella, Pedrazzini, Matteo, Ran, Xinru, Mak, Timothy S H, Crotti, Lia, Sham, Pak C, Torre, Eleonora, Zaza, Antonio, Schwartz, Peter J, Tse, Hung-Fat, Gnecchi, Massimiliano

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Predicting mendelian disease-causing non-synonymous single nucleotide variants in exome sequencing studies von Li, Miao-Xin, Kwan, Johnny S H, Bao, Su-Ying, Yang, Wanling, Ho, Shu-Leong, Song, Yong-Qiang, Sham, Pak C

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DIPPER, a spatiotemporal proteomics atlas of human intervertebral discs for exploring ageing and degeneration dynamics von Tam, Vivian, Chen, Peikai, Yee, Anita, Solis, Nestor, Klein, Theo, Kudelko, Mateusz, Sharma, Rakesh, Chan, Wilson C. W., Overall, Christopher M., Haglund, Lisbet, Sham, Pak C., Cheah, Kathryn Song Eng, Chan, Danny

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Estimating indirect parental genetic effects on offspring phenotypes using virtual parental genotypes derived from sibling and half sibling pairs von Hwang, Liang-Dar, Tubbs, Justin D., Luong, Justin, Lundberg, Mischa, Moen, Gunn-Helen, Wang, Geng, Warrington, Nicole M., Sham, Pak C., Cuellar-Partida, Gabriel, Evans, David M.

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Evaluating the heritability explained by known susceptibility variants: a survey of ten complex diseases von So, Hon-Cheong, Gui, Allen H.S., Cherny, Stacey S., Sham, Pak C.

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HYST: A Hybrid Set-Based Test for Genome-wide Association Studies, with Application to Protein-Protein Interaction-Based Association Analysis von Li, Miao-Xin, Kwan, Johnny S.H., Sham, Pak C.

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Directed Differentiation of Notochord-like and Nucleus Pulposus-like Cells Using Human Pluripotent Stem Cells von Zhang, Yuelin, Zhang, Zhao, Chen, Peikai, Ma, Chui Yan, Li, Cheng, Au, Tiffany Y.K., Tam, Vivian, Peng, Yan, Wu, Ron, Cheung, Kenneth Man Chee, Sham, Pak C., Tse, Hung-fat, Chan, Danny, Leung, Victor Y., Cheah, Kathryn S.E., Lian, Qizhou

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Excellent school performance at age 16 and risk of adult bipolar disorder: national cohort study von MacCabe, James H., Lambe, Mats P., Cnattingius, Sven, Sham, Pak C., David, Anthony S., Reichenberg, Abraham, Murray, Robin M., Hultman, Christina M.

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The genetic basis of onset age in schizophrenia: evidence and models von Zhan, Na, Sham, Pak C, So, Hon-Cheong, Lui, Simon S Y

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Interplay between Schizophrenia Polygenic Risk Score and Childhood Adversity in First-Presentation Psychotic Disorder: A Pilot Study von Trotta, Antonella, Iyegbe, Conrad, Di Forti, Marta, Sham, Pak C, Campbell, Desmond D, Cherny, Stacey S, Mondelli, Valeria, Aitchison, Katherine J, Murray, Robin M, Vassos, Evangelos, Fisher, Helen L

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Actionable secondary findings from whole-genome sequencing of 954 East Asians von Tang, Clara Sze-man, Dattani, Saloni, So, Man-ting, Cherny, Stacey S., Tam, Paul K. H., Sham, Pak C., Garcia-Barcelo, Maria-Mercè

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Stress and Psychological Distress among SARS Survivors 1 Year after the Outbreak von Lee, Antoinette M, Wong, Josephine GWS, McAlonan, Grainne M, Cheung, Vinci, Cheung, Charlton, Sham, Pak C, Chu, Chung-Ming, Wong, Poon-Chuen, Tsang, Kenneth WT, Chua, Siew E

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Common and rare variant associations with latent traits underlying depression, bipolar disorder, and schizophrenia von Dattani, Saloni, Sham, Pak C., Jermy, Bradley S., Coleman, Jonathan R. I., Howard, David M., Lewis, Cathryn M.

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