The Toll-Like Receptor 5 Agonist Entolimod Mitigates Lethal Acute Radiation Syndrome in Non-Human Primates von Krivokrysenko, Vadim I, Toshkov, Ilia A, Gleiberman, Anatoli S, Krasnov, Peter, Shyshynova, Inna, Bespalov, Ivan, Maitra, Ratan K, Narizhneva, Natalya V, Singh, Vijay K, Whitnall, Mark H, Purmal, Andrei A, Shakhov, Alexander N, Gudkov, Andrei V, Feinstein, Elena

Volltext

Prevention and mitigation of acute radiation syndrome in mice by synthetic lipopeptide agonists of Toll-like receptor 2 (TLR2) von Shakhov, Alexander N, Singh, Vijay K, Bone, Frederick, Cheney, Alec, Kononov, Yevgeniy, Krasnov, Peter, Bratanova-Toshkova, Troitza K, Shakhova, Vera V, Young, Jason, Weil, Michael M, Panoskaltsis-Mortari, Angela, Orschell, Christie M, Baker, Patricia S, Gudkov, Andrei, Feinstein, Elena

Volltext

Resistance of bone marrow stroma to genotoxic preconditioning is determined by p53 von Fedtsova, Natalia, Komarova, Elena A., Greene, Kellee F., Novototskaya, Liliya R., Molodtsov, Ivan, Brackett, Craig M., Strom, Evguenia, Gleiberman, Anatoli S., Shakhov, Alexander N., Gudkov, Andrei V.

Volltext

Distinct Role of Surface Lymphotoxin Expressed by B Cells in the Organization of Secondary Lymphoid Tissues von Tumanov, Alexei V., Kuprash, Dmitry V., Lagarkova, Maria A., Grivennikov, Sergei I., Abe, Koichiro, Shakhov, Alexander N., Drutskaya, Ludmila N., Stewart, Colin L., Chervonsky, Alexander V., Nedospasov, Sergei A.

Volltext

Dissecting the role of lymphotoxin in lymphoid organs by conditional targeting von Tumanov, Alexei V., Grivennikov, Sergei I., Shakhov, Alexander N., Rybtsov, Stanislav A., Koroleva, Ekaterina P., Takeda, Junji, Nedospasov, Sergei A., Kuprash, Dmitry V.

Volltext

Novel tumor necrosis factor‐knockout mice that lack Peyer's patches von Kuprash, Dmitry V., Tumanov, Alexei V., Liepinsh, Dmitry J., Koroleva, Ekaterina P., Drutskaya, Marina S., Kruglov, Andrei A., Shakhov, Alexander N., Southon, Eileen, Murphy, William J., Tessarollo, Lino, Grivennikov, Sergei I., Nedospasov, Sergei A.

Volltext

Identification of granulocyte colony-stimulating factor and interleukin-6 as candidate biomarkers of CBLB502 efficacy as a medical radiation countermeasure von Krivokrysenko, Vadim I, Shakhov, Alexander N, Singh, Vijay K, Bone, Frederick, Kononov, Yevgeniy, Shyshynova, Inna, Cheney, Alec, Maitra, Ratan K, Purmal, Andrei, Whitnall, Mark H, Gudkov, Andrei V, Feinstein, Elena

Volltext

Distinct and Nonredundant In Vivo Functions of TNF Produced by T Cells and Macrophages/Neutrophils: Protective and Deleterious Effects von Grivennikov, Sergei I., Tumanov, Alexei V., Liepinsh, Dmitry J., Kruglov, Andrei A., Marakusha, Boris I., Shakhov, Alexander N., Murakami, Takaya, Drutskaya, Ludmila N., Förster, Irmgard, Clausen, Björn E., Tessarollo, Lino, Ryffel, Bernhard, Kuprash, Dmitry V., Nedospasov, Sergei A.

Volltext

SMUCKLER/TIM4 is a distinct member of TIM family expressed by stromal cells of secondary lymphoid tissues and associated with lymphotoxin signaling von Shakhov, Alexander N., Rybtsov, Stanislav, Tumanov, Alexei V., Shulenin, Sergey, Dean, Michael, Kuprash, Dmitry V., Nedospasov, Sergei A.

Volltext

Redundancy in Tumor Necrosis Factor (TNF) and Lymphotoxin (LT) Signaling In Vivo: Mice with Inactivation of the Entire TNF/LT Locus versus Single-Knockout Mice von Kuprash, Dmitry V., Alimzhanov, Marat B., Tumanov, Alexei V., Grivennikov, Sergei I., Shakhov, Alexander N., Drutskaya, Ludmila N., Marino, Michael W., Turetskaya, Regina L., Anderson, Arthur O., Rajewsky, Klaus, Pfeffer, Klaus, Nedospasov, Sergei A.

Volltext

Accelerated thymic atrophy as a result of elevated homeostatic expression of the genes encoded by the TNF/lymphotoxin cytokine locus von Liepinsh, Dmitry J., Kruglov, Andrei A., Galimov, Arthur R., Shakhov, Alexander N., Shebzukhov, Yuriy V., Kuchmiy, Anna A., Grivennikov, Sergei I., Tumanov, Alexei V., Drutskaya, Marina S., Feigenbaum, Lionel, Kuprash, Dmitry V., Nedospasov, Sergei A.

Volltext

Distinct contributions of TNF and LT cytokines to the development of dendritic cells in vitro and their recruitment in vivo von Abe, Koichiro, Yarovinsky, Felix O., Murakami, Takaya, Shakhov, Alexander N., Tumanov, Alexei V., Ito, Daisuke, Drutskaya, Ludmila N., Pfeffer, Klaus, Kuprash, Dmitry V., Komschlies, Kristin L., Nedospasov, Sergei A.

Volltext

Gene profiling approach in the analysis of lymphotoxin and TNF deficiencies von Shakhov, Alexander N., Lyakhov, Ilya G., Tumanov, Alexei V., Rubtsov, Anatoly V., Drutskaya, Ludmila N., Marino, Michael W., Nedospasov, Sergei A.

Volltext

Expression profiling in knockout mice: lymphotoxin versus tumor necrosis factor in the maintenance of splenic microarchitecture von Shakhov, Alexander N, Nedospasov, Sergei A

Volltext

Kappa B-type enhancers are involved in lipopolysaccharide-mediated transcriptional activation of the tumor necrosis factor alpha gene in primary macrophages von Shakhov, A N, Collart, M A, Vassalli, P, Nedospasov, S A, Jongeneel, C V

Volltext

Role of interferon-gamma in interleukin 12-induced pathology in mice von Car, BD, Eng, VM, Schnyder, B, LeHir, M, Shakhov, AN, Woerly, G, Huang, S, Aguet, M, Anderson, TD, Ryffel, B

Volltext

Superantigen-induced immune stimulation amplifies mouse mammary tumor virus infection and allows virus transmission von Held, Werner, Waanders, Gary A., Shakhov, Alexander N., Scarpellino, Léonardo, Acha-Orbea, Hans, MacDonald, H. Robson

Volltext

Mice with a targeted mutation in lymphotoxin-alpha exhibit enhanced tumor growth and metastasis: impaired NK cell development and recruitment von Ito, D, Back, T C, Shakhov, A N, Wiltrout, R H, Nedospasov, S A

Volltext

Superantigen-reactive CD4+ T cells are required to stimulate B cells after infection with mouse mammary tumor virus von HELD, W, SHAKHOV, A. N, IZUI, S, WAANDERS, G. A, SCARPELLINO, L, MACDONALD, H. R, ACHA-ORBEA, H

Volltext

Clonal deletion of V β814-bearing T cells in mice transgenic for mammary tumour virus von Acha-Orbea, Hans, Shakhov, Alexander N., Scarpellino, Leo, Kolb, Edith, Müller, Vreni, Vessaz-Shaw, Annelyse, Fuchs, Regula, Blöchlinger, Karen, Rollini, Pierre, Billotte, Jerome, Sarafidou, Maria, MacDonald, H. Robson, Diggelmann, Heidi

Volltext