TanCAR: A Novel Bispecific Chimeric Antigen Receptor for Cancer Immunotherapy von Grada, Zakaria, Hegde, Meenakshi, Byrd, Tiara, Shaffer, Donald R, Ghazi, Alexia, Brawley, Vita S, Corder, Amanda, Schönfeld, Kurt, Koch, Joachim, Dotti, Gianpietro, Heslop, Helen E, Gottschalk, Stephen, Wels, Winfried S, Baker, Matthew L, Ahmed, Nabil

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Antitumor Effects of Chimeric Receptor Engineered Human T Cells Directed to Tumor Stroma von Kakarla, Sunitha, Chow, Kevin KH, Mata, Melinda, Shaffer, Donald R, Song, Xiao-Tong, Wu, Meng-Fen, Liu, Hao, Wang, Lisa L, Rowley, David R, Pfizenmaier, Klaus, Gottschalk, Stephen

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T Cells Redirected to EphA2 for the Immunotherapy of Glioblastoma von Chow, Kevin KH, Naik, Swati, Kakarla, Sunitha, Brawley, Vita S, Shaffer, Donald R, Yi, Zhongzhen, Rainusso, Nino, Wu, Meng-Fen, Liu, Hao, Kew, Yvonne, Grossman, Robert G, Powell, Suzanne, Lee, Dean, Ahmed, Nabil, Gottschalk, Stephen

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Crosstalk between medulloblastoma cells and endothelium triggers a strong chemotactic signal recruiting T lymphocytes to the tumor microenvironment von Salsman, Vita S, Chow, Kevin K H, Shaffer, Donald R, Kadikoy, Huseyin, Li, Xiao-Nan, Gerken, Claudia, Perlaky, Laszlo, Metelitsa, Leonid S, Gao, Xiuhua, Bhattacharjee, Meena, Hirschi, Karen, Heslop, Helen E, Gottschalk, Stephen, Ahmed, Nabil

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In vivo discovery of immunotherapy targets in the tumour microenvironment von Zhou, Penghui, Shaffer, Donald R., Alvarez Arias, Diana A., Nakazaki, Yukoh, Pos, Wouter, Torres, Alexis J., Cremasco, Viviana, Dougan, Stephanie K., Cowley, Glenn S., Elpek, Kutlu, Brogdon, Jennifer, Lamb, John, Turley, Shannon J., Ploegh, Hidde L., Root, David E., Love, J. Christopher, Dranoff, Glenn, Hacohen, Nir, Cantor, Harvey, Wucherpfennig, Kai W.

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Inhibition of LILRB2 by a Novel Blocking Antibody Designed to Reprogram Immunosuppressive Macrophages to Drive T-Cell Activation in Tumors von Umiker, Ben, Hashambhoy-Ramsay, Yasmin, Smith, Jeff, Rahman, Tanzila, Mueller, Amy, Davidson, Rachel, Meyer, Christina, Patankar, Gayatri, Alam, Mohammad Murshid, Jaffe, Sarah, Krukenberg, Kristin, Goodman, Allison, Spaulding, Vikki, Priess, Michelle, Dhaneshwar, Abha, Wong, Masie, Diiorio, Alexa, O'Malley, Kristin, McGrath, Lara, Willer, Margaret, Pepper, Lauren, Gostissa, Monica, Kis-Toth, Katalin, Wiederschain, Dmitri, Cohen, Heather, Shaffer, Donald R

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PROTAC-mediated NR4A1 degradation as a novel strategy for cancer immunotherapy von Wang, Lei, Xiao, Yufeng, Luo, Yuewan, Master, Rohan P, Mo, Jiao, Kim, Myung-Chul, Liu, Yi, Maharjan, Chandra K, Patel, Urvi M, De, Umasankar, Carelock, Madison E, Tithi, Tanzia Islam, Li, Xiangming, Shaffer, Donald R, Guertin, Kevin R, Zhuang, Haoyang, Moser, Emily, Smalley, Keiran S M, Lv, Dongwen, Zhou, Daohong, Zheng, Guangrong, Zhang, Weizhou

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T cells redirected against CD70 for the immunotherapy of CD70-positive malignancies von Shaffer, Donald R., Savoldo, Barbara, Yi, Zhongzhen, Chow, Kevin K.H., Kakarla, Sunitha, Spencer, David M., Dotti, Gianpietro, Wu, Meng-Fen, Liu, Hao, Kenney, Shannon, Gottschalk, Stephen

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Differential expression of CCR8 in tumors versus normal tissue allows specific depletion of tumor-infiltrating T regulatory cells by GS-1811, a novel Fc-optimized anti-CCR8 antibod... von Weaver, Jessica D., Stack, Edward C., Buggé, Joshua A., Hu, Changyun, McGrath, Lara, Mueller, Amy, Wong, Masie, Klebanov, Boris, Rahman, Tanzila, Kaufman, Rosemary, Fregeau, Christine, Spaulding, Vikki, Priess, Michelle, Legendre, Kristen, Jaffe, Sarah, Upadhyay, Dhruvkumar, Singh, Anirudh, Xu, Chang-Ai, Krukenberg, Kristin, Zhang, Yan, Ezzyat, Yassine, Saddier Axe, Dorothée, Kuhne, Michelle R., Meehl, Michael A., Shaffer, Donald R., Weist, Brian M., Wiederschain, Dmitri, Depis, Fabien, Gostissa, Monica

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Generation of Polyclonal CMV-specific T Cells for the Adoptive Immunotherapy of Glioblastoma von GHAZI, Alexia, ASHOORI, Aidin, HEGDE, Meenakshi, LEEN, Ann M, BOLLARD, Catherine M, ROONEY, Cliona M, HESLOP, Helen E, GOTTSCHALK, Stephen, AHMED, Nabil, HANLEY, Patrick J, BRAWLEY, Vita S, SHAFFER, Donald R, KEW, Yvonne, POWELL, Suzanne Z, GROSSMAN, Robert, GRADA, Zakaria, SCHEURER, Michael E

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Milliken’s Bend: A Civil War Battle in History and Memory by Linda Barnickel (review) von Shaffer, Donald R

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Expansion of T cells targeting multiple antigens of cytomegalovirus, Epstein–Barr virus and adenovirus to provide broad antiviral specificity after stem cell transplantation von Hanley, Patrick J, Shaffer, Donald R, Cruz, Conrad R.Y, Ku, Stephanie, Tzou, Benjamin, Liu, Hao, Demmler-Harrison, Gail, Heslop, Helen E, Rooney, Clio M, Gottschalk, Stephen, Bollard, Catherine M

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Bluejackets and Contrabands: African Americans and the Union Navy by Barbara Brooks Tomblin (review) von Shaffer, Donald R

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Genetic Modification of T Cells With IL-21 Enhances Antigen Presentation and Generation of Central Memory Tumor-specific Cytotoxic T-lymphocytes von KAKA, Anjum S, SHAFFER, Donald R, HARTMEIER, Ryan, LEEN, Ann M, AN LU, BEAR, Adham, ROONEY, Cliona M, FOSTER, Aaron E

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Foreign or Domestic CARs: Receptor Ligands as Antigen-Binding Domains von Shaffer, Donald, Zhou, Penghui, Gottschalk, Stephen

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Aggressive peripheral CD70-positive t-cell lymphoma associated with severe chronic active EBV infection von Shaffer, Donald R., Sheehan, Andrea M., Yi, Zhongzhen, Rodgers, Cheryl C., Bollard, Catherine M., Brenner, Malcolm K., Rooney, Cliona M., Heslop, Helen E., Gottschalk, Stephen

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Graduate students bring clinical know-how into their lab work through the HHMI Med into Grad program von Hartmaier, Ryan J, Shaffer, Donald R

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Dissecting the tumor micro-environment in triple negative breast cancer identifies a mutually exclusive expression pattern of the immune co-inhibitory molecules B7-H4 and PD-L1 von Shaffer, Donald R, Cortez-Retamozo, Virna, Nagashima, Kumiko, Zi, Tong, Shu, ChengYi J, Feldman, Igor, Neumeister, Veronique, Smith, Jeff, Zafari, Mohammad, Larson, Rebecca, Silver, Matthew, Mabry, Robert, Briskin, Michael, Novobrantseva, Tanya, Rimm, David, Sathyanarayanan, Sriram

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Abstract 5007: Preclinical evaluation of JTX-8064, an anti-LILRB2 antagonist antibody, for reprogramming tumor-associated macrophages von Cohen, Heather, Hashambhoy-Ramsay, Yasmin, Pepper, Lauren R., Smith, Jeffrey Y., Willer, Margaret, Guay, Kevin, Spaulding, Vikki, O'Malley, Kristin, Gostissa, Monica, Dhaneshwar, Abha, Stack, Edward C., Mora, Alessandro, Shaffer, Donald R.

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Abstract 4532: Preclinical evaluation of JTX-1811, an anti-CCR8 antibody with enhanced ADCC activity, for preferential depletion of tumor-infiltrating regulatory T cells von Dépis, Fabien, Hu, Changyun, Weaver, Jessica, McGrath, Lara, Klebanov, Boris, Buggé, Joshua, Umiker, Ben, Fregeau, Christine, Upadhyay, Dhruvkumar, Singh, Anirudh, Xu, Chang-Ai, Spaulding, Vikki, Priess, Michelle, Wong, Masie, Naheed, Seema, Zhang, Yan, Legendre, Kristin, Stack, Edward C., Mora, Alessandro, Willer, Margaret, Meetze, Kristan, Gostissa, Monica, Meehl, Michael A., Shaffer, Donald R.

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