Discovery of Potent and Selective RSK Inhibitors as Biological Probes von Jain, Rama, Mathur, Michelle, Lan, Jiong, Costales, Abran, Atallah, Gordana, Ramurthy, Savithri, Subramanian, Sharadha, Setti, Lina, Feucht, Paul, Warne, Bob, Doyle, Laura, Basham, Stephen, Jefferson, Anne B., Lindvall, Mika, Appleton, Brent A., Shafer, Cynthia M.

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Novel potent and selective inhibitors of p90 ribosomal S6 kinase reveal the heterogeneity of RSK function in MAPK-driven cancers von Aronchik, Ida, Appleton, Brent A, Basham, Stephen E, Crawford, Kenneth, Del Rosario, Mercedita, Doyle, Laura V, Estacio, William F, Lan, Jiong, Lindvall, Mika K, Luu, Catherine A, Ornelas, Elizabeth, Venetsanakos, Eleni, Shafer, Cynthia M, Jefferson, Anne B

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Discovery and optimization of novel pyridines as highly potent and selective glycogen synthase kinase 3 inhibitors von Ramurthy, Savithri, Pfister, Keith B., Boyce, Rustum S., Brown, Sean P., Costales, Abran Q., Desai, Manoj C., Fang, Eric, Levine, Barry H., Ng, Simon C., Nuss, John M., Ring, David B., Shafer, Cynthia M., Shu, Wei, Subramanian, Sharadha, Wagman, Allan S., Wang, Haixia, Bussiere, Dirksen E.

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Design and synthesis of potent RSK inhibitors von Jain, Rama, Mathur, Michelle, Lan, Jiong, Costales, Abran, Atallah, Gordana, Ramurthy, Savithri, Subramanian, Sharadha, Setti, Lina, Feucht, Paul, Warne, Bob, Doyle, Laura, Basham, Stephen, Jefferson, Anne B., Appleton, Brent A., Lindvall, Mika, Shafer, Cynthia M.

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Discovery of RAF265: A Potent mut-B-RAF Inhibitor for the Treatment of Metastatic Melanoma von Williams, Teresa E, Subramanian, Sharadha, Verhagen, Joelle, McBride, Christopher M, Costales, Abran, Sung, Leonard, Antonios-McCrea, William, McKenna, Maureen, Louie, Alicia K, Ramurthy, Savithri, Levine, Barry, Shafer, Cynthia M, Machajewski, Timothy, Renhowe, Paul A, Appleton, Brent A, Amiri, Payman, Chou, James, Stuart, Darrin, Aardalen, Kimberly, Poon, Daniel

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Design, Structure−Activity Relationships and in Vivo Characterization of 4-Amino-3-benzimidazol-2-ylhydroquinolin-2-ones: A Novel Class of Receptor Tyrosine Kinase Inhibitors von Renhowe, Paul A, Pecchi, Sabina, Shafer, Cynthia M, Machajewski, Timothy D, Jazan, Elisa M, Taylor, Clarke, Antonios-McCrea, William, McBride, Christopher M, Frazier, Kelly, Wiesmann, Marion, Lapointe, Gena R, Feucht, Paul H, Warne, Robert L, Heise, Carla C, Menezes, Daniel, Aardalen, Kimberly, Ye, Helen, He, Molly, Le, Vincent, Vora, Jayesh, Jansen, Johanna M, Wernette-Hammond, Mary Ellen, Harris, Alex L

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Imidazo[1,2-a]pyridin-6-yl-benzamide analogs as potent RAF inhibitors von Smith, Aaron, Ni, Zhi-Jie, Poon, Daniel, Huang, Zilin, Chen, Zheng, Zhang, Qiong, Tandeske, Laura, Merritt, Hanne, Shoemaker, Kevin, Chan, John, Kaufman, Susan, Huh, Kay, Murray, Jeremy, Appleton, Brent A., Cowan-Jacob, Sandra W., Scheufler, Clemens, Kanazawa, Takanori, Jansen, Johanna M., Stuart, Darrin, Shafer, Cynthia M.

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Design, Structure–Activity Relationship, and in Vivo Characterization of the Development Candidate NVP-HSP990 von McBride, Christopher M, Levine, Barry, Xia, Yi, Bellamacina, Cornelia, Machajewski, Timothy, Gao, Zhenhai, Renhowe, Paul, Antonios-McCrea, William, Barsanti, Paul, Brinner, Kristin, Costales, Abran, Doughan, Brandon, Lin, Xiaodong, Louie, Alicia, McKenna, Maureen, Mendenhall, Kris, Poon, Daniel, Rico, Alice, Wang, Michael, Williams, Teresa E, Abrams, Tinya, Fong, Susan, Hendrickson, Thomas, Lei, Dachuan, Lin, Julie, Menezes, Daniel, Pryer, Nancy, Taverna, Pietro, Xu, Yongjin, Zhou, Yasheen, Shafer, Cynthia M

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Design and synthesis of 6,6-fused heterocyclic amides as raf kinase inhibitors von Ramurthy, Savithri, Costales, Abran, Jansen, Johanna M., Levine, Barry, Renhowe, Paul A., Shafer, Cynthia M., Subramanian, Sharadha

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Optimization of 3‑Pyrimidin-4-yl-oxazolidin-2-ones as Orally Bioavailable and Brain Penetrant Mutant IDH1 Inhibitors von Zhao, Qian, Manning, James R., Sutton, James, Costales, Abran, Sendzik, Martin, Shafer, Cynthia M., Levell, Julian R., Liu, Gang, Caferro, Thomas, Cho, Young Shin, Palermo, Mark, Chenail, Gregg, Dooley, Julia, Villalba, Brian, Farsidjani, Ali, Chen, Jinyun, Dodd, Stephanie, Gould, Ty, Liang, Guiqing, Slocum, Kelly, Pu, Minying, Firestone, Brant, Growney, Joseph, Heimbach, Tycho, Pagliarini, Raymond

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Mechanism for Acivicin Inactivation of Triad Glutamine Amidotransferases von Chittur, Sridar V, Klem, Thomas J, Shafer, Cynthia M, Davisson, V. Jo

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Correction to Design and Synthesis of Orally Bioavailable Benzimidazole Reverse Amides as Pan RAF Kinase Inhibitors von Subramanian, Sharadha, Costales, Abran, Williams, Teresa E, Levine, Barry, McBride, Christopher M, Poon, Daniel, Amiri, Payman, Renhowe, Paul A, Shafer, Cynthia M, Stuart, Darrin, Verhagen, Joelle, Ramurthy, Savithri

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3-Benzimidazol-2-yl-1H-indazoles as potent c-ABL inhibitors von MCBRIDE, Christopher M, RENHOWE, Paul A, GESNER, Thomas G, JANSEN, Johanna M, JULIE LIN, MA, Sylvia, ZHOU, Yasheen, SHAFER, Cynthia M

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Monosubstituted Oxazoles. 1. Synthesis of 5-Substituted Oxazoles by Directed Alkylation von Shafer, Cynthia M, Molinski, Tadeusz F

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Oxidative Rearrangement of 2-Substituted Oxazolines. A Novel Entry to 5,6-Dihydro-2H-1,4-oxazin-2-ones and Morpholin-2-ones von Shafer, Cynthia M, Molinski, Tadeusz F

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Progress towards the total synthesis of Bengazole A, an antifungal natural product from a marine sponge Jaspis sp. by Cynthia Marie Shafer von Shafer, Cynthia Marie

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Iron and bronze production in Iron Age IIA Philistia: new evidence from Tell es-Safi/Gath, Israel von Eliyahu-Behar, Adi, Yahalom-Mack, Naama, Shilstein, Sana, Zukerman, Alexander, Shafer-Elliott, Cynthia, Maeir, Aren M., Boaretto, Elisabetta, Finkelstein, Israel, Weiner, Steve

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Inhibition of Cdc7/Dbf4 kinase activity affects specific phosphorylation sites on MCM2 in cancer cells von Charych, Deborah H., Coyne, Mazie, Yabannavar, Asha, Narberes, Jamie, Chow, Sylvia, Wallroth, Marco, Shafer, Cynthia, Walter, Annette O.

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The Daily Bread at Tell Halif: An Overview of Food Production and Consumption von Cynthia Shafer-Elliott, Tim Frank, Oded Borowski

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LHMDS mediated tandem acylation–cyclization of 2-aminobenzenecarbonitriles with 2-benzymidazol-2-yl acetates: a short and efficient route to the synthesis of 4-amino-3-benzimidazol... von Antonios-McCrea, William R., Frazier, Kelly A., Jazan, Elisa M., Machajewski, Timothy D., McBride, Christopher M., Pecchi, Sabina, Renhowe, Paul A., Shafer, Cynthia M., Taylor, Clarke

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