A bispecific IgG format containing four independent antigen binding sites von Ljungars, Anne, Schiött, Torbjörn, Mattson, Ulrika, Steppa, Jessica, Hambe, Björn, Semmrich, Monika, Ohlin, Mats, Tornberg, Ulla-Carin, Mattsson, Mikael

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Vectorized Treg-depleting αCTLA-4 elicits antigen cross-presentation and CD8+ T cell immunity to reject ‘cold’ tumors von Semmrich, Monika, Marchand, Jean-Baptiste, Fend, Laetitia, Rehn, Matilda, Remy, Christelle, Holmkvist, Petra, Silvestre, Nathalie, Svensson, Carolin, Kleinpeter, Patricia, Deforges, Jules, Junghus, Fred, Cleary, Kirstie L, Bodén, Mimoza, Mårtensson, Linda, Foloppe, Johann, Teige, Ingrid, Quéméneur, Eric, Frendéus, Björn

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1368 Preclinical development of an agonistic anti-TNFR2 antibody (BI-1910) for cancer immunotherapy von Martensson, Linda, Holmkvist, Petra, Kovacek, Mathilda, Svensson, Carolin, Bodén, Mimoza, Cleary, Kirstie, Dadas, Osman, Blidberg, Therese, Duell, Benjamin, Semmrich, Monika, Nilsson, Jan Anders, Beers, Stephen, Lim, Sean, Wallin, Johan E, Borggren, Marie, McAllister, Andres, Cragg, Mark, Karlsson, Ingrid, Frendeus, Bjorn, Teige, Ingrid

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Domain binding and isotype dictate the activity of anti-human OX40 antibodies von Griffiths, Jordana, Hussain, Khiyam, Smith, Hannah L, Sanders, Theodore, Cox, Kerry L, Semmrich, Monika, Mårtensson, Linda, Kim, Jinny, Inzhelevskaya, Tatyana, Penfold, Chris A, Tutt, Alison L, Mockridge, C Ian, Chan, HT Claude, English, Vikki, French, Ruth F, Teige, Ingrid, Al-Shamkhani, Aymen, Glennie, Martin J, Frendeus, Bjorn L, Willoughby, Jane E, Cragg, Mark S

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Importance of integrin LFA-1 deactivation for the generation of immune responses von Semmrich, Monika, Smith, Andrew, Feterowski, Carolin, Beer, Sandra, Engelhardt, Britta, Busch, Dirk H, Bartsch, Bernadett, Laschinger, Melanie, Hogg, Nancy, Pfeffer, Klaus, Holzmann, Bernhard

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594 BT-001, an oncolytic vaccinia virus armed with a Treg-depleting human recombinant anti-CTLA4 antibody and GM-CSF to target the tumor microenvironment von Semmrich, Monika, Marchand, Jean-Baptiste, Fend, Laetitia, Rehn, Matilda, Silvestre, Nathalie, Mårtensson, Linda, Foloppe, Johann, Teige, Ingrid, Quéméneur, Eric, Frendeus, Björn

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725 Pre-clinical development of TNFR2 ligand-blocking BI-1808 for cancer immunotherapy von Mårtensson, Linda, Kovacek, Mathilda, Holmkvist, Petra, Semmrich, Monika, Svensson, Carolin, Blidberg, Therese, Roos, Carl, McAllister, Andres, Demiri, Mimoza, Borggren, Marie, Karlsson, Ingrid, Frendeus, Björn, Teige, Ingrid

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Intact LFA-1 deactivation promotes T-cell activation and rejection of cardiac allograft von Hüser, Norbert, Fasan, Annette, Semmrich, Monika, Schmidbauer, Patricia, Holzmann, Bernhard, Laschinger, Melanie

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IRF4 Transcription-Factor-Dependent CD103+CD11b+ Dendritic Cells Drive Mucosal T Helper 17 Cell Differentiation von Persson, Emma K., Uronen-Hansson, Heli, Semmrich, Monika, Rivollier, Aymeric, Hägerbrand, Karin, Marsal, Jan, Gudjonsson, Sigurdur, Håkansson, Ulf, Reizis, Boris, Kotarsky, Knut, Agace, William W.

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Antibodies to Costimulatory Receptor 4-1BB Enhance Anti-tumor Immunity via T Regulatory Cell Depletion and Promotion of CD8 T Cell Effector Function von Buchan, Sarah L., Dou, Lang, Remer, Marcus, Booth, Steven G., Dunn, Stuart N., Lai, Chester, Semmrich, Monika, Teige, Ingrid, Mårtensson, Linda, Penfold, Christine A., Chan, H.T. Claude, Willoughby, Jane E., Mockridge, C. Ian, Dahal, Lekh N., Cleary, Kirstie L.S., James, Sonya, Rogel, Anne, Kannisto, Päivi, Jernetz, Mats, Williams, Emily L., Healy, Eugene, Verbeek, J. Sjef, Johnson, Peter W.M., Frendéus, Björn, Cragg, Mark S., Glennie, Martin J., Gray, Juliet C., Al-Shamkhani, Aymen, Beers, Stephen A.

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Abstract 5602: BT-001, an oncolytic vaccinia virus armed with a Treg-depletion-optimized recombinant human anti-CTLA4 antibody and GM-CSF to target the tumor microenvironment von Marchand, Jean-Baptiste, Semmrich, Monika, Fend, Laetitia, Rehn, Matilda, Silvestre, Nathalie, Teige, Ingrid, Foloppe, Johann, Mårtensson, Linda, Quéméneur, Eric, Frendeus, Björn

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Abstract 936: Targeting TNFR2 for cancer immunotherapy: Ligand blocking depletors versus receptor agonists von Mårtensson, Linda, Cleary, Kirstie, Semmrich, Monika, Kovacek, Mathilda, Holmkvist, Petra, Svensson, Caroline, Demiri, Mimoza, Blidberg, Therese, Thornberg, Ulla-Carin, Pitic, Vincentiu, Dadas, Osman, Lim, Sean H., Beers, Stephen A., Cragg, Mark S., Frendéus, Björn, Teige, Ingrid

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Directed antigen targeting in vivo identifies a role for CD103+ dendritic cells in both tolerogenic and immunogenic T-cell responses von Semmrich, M, Plantinga, M, Svensson-Frej, M, Uronen-Hansson, H, Gustafsson, T, Mowat, A M, Yrlid, U, Lambrecht, B N, Agace, W W

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Integrin subunit CD18 Is the T-lymphocyte receptor for the Helicobacter pylori vacuolating cytotoxin von Sewald, Xaver, Gebert-Vogl, Bettina, Prassl, Sandra, Barwig, Iris, Weiss, Evelyn, Fabbri, Monica, Osicka, Radim, Schiemann, Matthias, Busch, Dirk H, Semmrich, Monika, Holzmann, Bernhard, Sebo, Peter, Haas, Rainer

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Abstract 3567: Comprehensive preclinical studies of BT-001: An oncolytic vaccinia virus armed with Treg-depleting @CTLA4 and GM-CSF von Marchand, Jean-Baptiste, Semmrich, Monika, Ziller, Christelle, Rehn, Matilda, Fend, Laetitia, Holmkvist, Petra, Silvestre, Nathalie, Svensson, Carolin, Patricia, Kleinpeter, Deforges, Jules, Junghus, Fred, Mårtensson, Linda, Foloppe, Johann, Teige, Ingrid, Frendéus, Björn, Quéméneur, Eric

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Abstract 4156: BI-1808 - a first in class ligand-blocking αTNFR2 antibody for cancer immunotherapy von Mårtensson, Linda, Cleary, Kirsty, Holmkvist, Petra, Kovacek, Mathilda, Svensson, Carolin, Semmrich, Monika, Blidberg, Therese, Demiri, Mimoza, Dadas, Osman, Borggren, Marie, Pitic, Vici, Lim, Sean H., Beers, Stephen A., Gertsson, Susanne, Rohrberg, Kristoffer S., Karlsson, Ingrid, McAllister, Andres, Cragg, Mark S., Frendeus, Björn, Teige, Ingrid

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RhoH is important for positive thymocyte selection and T-cell receptor signaling von Dorn, Tatjana, Kuhn, Ursula, Bungartz, Gerd, Stiller, Sebastian, Bauer, Martina, Ellwart, Joachim, Peters, Thorsten, Scharffetter-Kochanek, Karin, Semmrich, Monika, Laschinger, Melanie, Holzmann, Bernhard, Klinkert, Wolfgang E.F., Straten, Per Thor, Køllgaard, Tania, Sixt, Michael, Brakebusch, Cord

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Design and Synthesis of Potent and Selective α4β7 Integrin Antagonists von Boer, Jürgen, Gottschling, Dirk, Schuster, Anja, Semmrich, Monika, Holzmann, Bernhard, Kessler, Horst

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Agonistic anti TNFR2 antibody molecules von Holmkvist, Petra, Semmrich, Monika, Frendéus, Björn, Teige, Ingrid, Mårtensson, Linda

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NOVEL COMBINATIONS OF ANTIBODIES AND USES THEREOF von SEMMRICH, Monika, FRENDÉUS, Björn, MARCHAND, Jean-Baptiste, REHN, Matilda, MÅRTENSSON, Linda

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