Rapid incorporation of Favipiravir by the fast and permissive viral RNA polymerase complex results in SARS-CoV-2 lethal mutagenesis von Shannon, Ashleigh, Selisko, Barbara, Le, Nhung-Thi-Tuyet, Huchting, Johanna, Touret, Franck, Piorkowski, Géraldine, Fattorini, Véronique, Ferron, François, Decroly, Etienne, Meier, Chris, Coutard, Bruno, Peersen, Olve, Canard, Bruno

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In vitro reconstitution of SARS-coronavirus mRNA cap methylation von Bouvet, Mickaël, Debarnot, Claire, Imbert, Isabelle, Selisko, Barbara, Snijder, Eric J, Canard, Bruno, Decroly, Etienne

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A dual mechanism of action of AT-527 against SARS-CoV-2 polymerase von Shannon, Ashleigh, Fattorini, Véronique, Sama, Bhawna, Selisko, Barbara, Feracci, Mikael, Falcou, Camille, Gauffre, Pierre, El Kazzi, Priscila, Delpal, Adrien, Decroly, Etienne, Alvarez, Karine, Eydoux, Cécilia, Guillemot, Jean-Claude, Moussa, Adel, Good, Steven S., La Colla, Paolo, Lin, Kai, Sommadossi, Jean-Pierre, Zhu, Yingxiao, Yan, Xiaodong, Shi, Hui, Ferron, François, Canard, Bruno

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The methyltransferase domain of dengue virus protein NS5 ensures efficient RNA synthesis initiation and elongation by the polymerase domain von Potisopon, Supanee, Priet, Stéphane, Collet, Axelle, Decroly, Etienne, Canard, Bruno, Selisko, Barbara

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Regulation of Flavivirus RNA synthesis and replication von Selisko, Barbara, Wang, Chunling, Harris, Eva, Canard, Bruno

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Structural and Functional Basis of the Fidelity of Nucleotide Selection by Flavivirus RNA-Dependent RNA Polymerases von Selisko, Barbara, Papageorgiou, Nicolas, Ferron, François, Canard, Bruno

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Nuclear Localization of Dengue Virus Nonstructural Protein 5 Does Not Strictly Correlate with Efficient Viral RNA Replication and Inhibition of Type I Interferon Signaling von Kumar, Anil, Bühler, Sandra, Selisko, Barbara, Davidson, Andrew, Mulder, Klaas, Canard, Bruno, Miller, Sven, Bartenschlager, Ralf

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Coronavirus Nonstructural Protein 16 Is a Cap-0 Binding Enzyme Possessing (Nucleoside-2′O)-Methyltransferase Activity von DECROLY, Etienne, IMBERT, Isabelle, COUTARD, Bruno, BOUVET, Mickaël, SELISKO, Barbara, ALVAREZ, Karine, GORBALENYA, Alexander E, SNIJDER, Eric J, CANARD, Bruno

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Structure and functionality in flavivirus NS-proteins: Perspectives for drug design von Bollati, Michela, Alvarez, Karin, Assenberg, René, Baronti, Cécile, Canard, Bruno, Cook, Shelley, Coutard, Bruno, Decroly, Etienne, de Lamballerie, Xavier, Gould, Ernest A., Grard, Gilda, Grimes, Jonathan M., Hilgenfeld, Rolf, Jansson, Anna M., Malet, Hélène, Mancini, Erika J., Mastrangelo, Eloise, Mattevi, Andrea, Milani, Mario, Moureau, Grégory, Neyts, Johan, Owens, Raymond J., Ren, Jingshan, Selisko, Barbara, Speroni, Silvia, Steuber, Holger, Stuart, David I., Unge, Torsten, Bolognesi, Martino

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Structural and Functional Analysis of Methylation and 5′-RNA Sequence Requirements of Short Capped RNAs by the Methyltransferase Domain of Dengue Virus NS5 von Egloff, Marie-Pierre, Decroly, Etienne, Malet, Hélène, Selisko, Barbara, Benarroch, Delphine, Ferron, François, Canard, Bruno

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Molecular basis for nucleotide conservation at the ends of the dengue virus genome von Selisko, Barbara, Potisopon, Supanee, Agred, Rym, Priet, Stéphane, Varlet, Isabelle, Thillier, Yann, Sallamand, Corinne, Debart, Françoise, Vasseur, Jean-Jacques, Canard, Bruno

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Crystal Structure of the RNA Polymerase Domain of the West Nile Virus Non-structural Protein 5 von Malet, Hélène, Egloff, Marie-Pierre, Selisko, Barbara, Butcher, Rebecca E., Wright, Peter J., Roberts, Michael, Gruez, Arnaud, Sulzenbacher, Gerlind, Vonrhein, Clemens, Bricogne, Gérard, Mackenzie, Jason M., Khromykh, Alexander A., Davidson, Andrew D., Canard, Bruno

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Simeprevir Potently Suppresses SARS-CoV‑2 Replication and Synergizes with Remdesivir von Lo, Ho Sing, Hui, Kenrie Pui Yan, Lai, Hei-Ming, He, Xu, Khan, Khadija Shahed, Kaur, Simranjeet, Huang, Junzhe, Li, Zhongqi, Chan, Anthony K. N, Cheung, Hayley Hei-Yin, Ng, Ka-Chun, Ho, John Chi Wang, Chen, Yu Wai, Ma, Bowen, Cheung, Peter Man-Hin, Shin, Donghyuk, Wang, Kaidao, Lee, Meng-Hsuan, Selisko, Barbara, Eydoux, Cecilia, Guillemot, Jean-Claude, Canard, Bruno, Wu, Kuen-Phon, Liang, Po-Huang, Dikic, Ivan, Zuo, Zhong, Chan, Francis K. L, Hui, David S. C, Mok, Vincent C. T, Wong, Kam-Bo, Mok, Chris Ka Pun, Ko, Ho, Aik, Wei Shen, Chan, Michael Chi Wai, Ng, Wai-Lung

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Inhibition of Arenaviridae nucleoprotein exonuclease by bisphosphonate von Nguyen, Thi Hong Van, Yekwa, Elsie, Selisko, Barbara, Canard, Bruno, Alvarez, Karine, Ferron, François

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The RNA template channel of the RNA-dependent RNA polymerase as a target for development of antiviral therapy of multiple genera within a virus family von van der Linden, Lonneke, Vives-Adrián, Laia, Selisko, Barbara, Ferrer-Orta, Cristina, Liu, Xinran, Lanke, Kjerstin, Ulferts, Rachel, De Palma, Armando M, Tanchis, Federica, Goris, Nesya, Lefebvre, David, De Clercq, Kris, Leyssen, Pieter, Lacroix, Céline, Pürstinger, Gerhard, Coutard, Bruno, Canard, Bruno, Boehr, David D, Arnold, Jamie J, Cameron, Craig E, Verdaguer, Nuria, Neyts, Johan, van Kuppeveld, Frank J M

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The Crystal Structure of Coxsackievirus B3 RNA-Dependent RNA Polymerase in Complex with Its Protein Primer VPg Confirms the Existence of a Second VPg Binding Site on Picornaviridae... von Gruez, Arnaud, Selisko, Barbara, Roberts, Michael, Bricogne, Gérard, Bussetta, Cécile, Jabafi, Ilham, Coutard, Bruno, De Palma, Armando M, Neyts, Johan, Canard, Bruno

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Comparative mechanistic studies of de novo RNA synthesis by flavivirus RNA-dependent RNA polymerases von Selisko, Barbara, Dutartre, Hélène, Guillemot, Jean-Claude, Debarnot, Claire, Benarroch, Delphine, Khromykh, Alexander, Desprès, Philippe, Egloff, Marie-Pierre, Canard, Bruno

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De Novo Initiation of RNA Synthesis by the Arterivirus RNA-Dependent RNA Polymerase von Beerens, Nancy, Selisko, Barbara, Ricagno, Stefano, Imbert, Isabelle, van der Zanden, Linda, Snijder, Eric J, Canard, Bruno

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Virtual screening and bioassay study of novel inhibitors for dengue virus mRNA cap (nucleoside-2′ O)-methyltransferase von Luzhkov, Victor B., Selisko, Barbara, Nordqvist, Anneli, Peyrane, Frédéric, Decroly, Etienne, Alvarez, Karine, Karlen, Anders, Canard, Bruno, Åqvist, Johan

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Remdesivir and SARS-CoV-2: Structural requirements at both nsp12 RdRp and nsp14 Exonuclease active-sites von Shannon, Ashleigh, Le, Nhung Thi-Tuyet, Selisko, Barbara, Eydoux, Cecilia, Alvarez, Karine, Guillemot, Jean-Claude, Decroly, Etienne, Peersen, Olve, Ferron, Francois, Canard, Bruno

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