Advances in the Genetic Basis and Pathogenesis of Sarcomere Cardiomyopathies von Yotti, Raquel, Seidman, Christine E, Seidman, Jonathan G

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Genomic frontiers in congenital heart disease von Morton, Sarah U., Quiat, Daniel, Seidman, Jonathan G., Seidman, Christine E.

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Clinical and Mechanistic Insights Into the Genetics of Cardiomyopathy von Burke, Michael A., MD, Cook, Stuart A., MD, PhD, Seidman, Jonathan G., PhD, Seidman, Christine E., MD

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A small-molecule inhibitor of sarcomere contractility suppresses hypertrophic cardiomyopathy in mice von Green, Eric M., Wakimoto, Hiroko, Anderson, Robert L., Evanchik, Marc J., Gorham, Joshua M., Harrison, Brooke C., Henze, Marcus, Kawas, Raja, Oslob, Johan D., Rodriguez, Hector M., Song, Yonghong, Wan, William, Leinwand, Leslie A., Spudich, James A., McDowell, Robert S., Seidman, J. G., Seidman, Christine E.

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Titin mutations in iPS cells define sarcomere insufficiency as a cause of dilated cardiomyopathy von Hinson, John T., Chopra, Anant, Nafissi, Navid, Polacheck, William J., Benson, Craig C., Swist, Sandra, Gorham, Joshua, Yang, Luhan, Schafer, Sebastian, Sheng, Calvin C., Haghighi, Alireza, Homsy, Jason, Hubner, Norbert, Church, George, Cook, Stuart A., Linke, Wolfgang A., Chen, Christopher S., Seidman, J. G., Seidman, Christine E.

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Myocardial Fibrosis as an Early Manifestation of Hypertrophic Cardiomyopathy von Ho, Carolyn Y, López, Begoña, Coelho-Filho, Otavio R, Lakdawala, Neal K, Cirino, Allison L, Jarolim, Petr, Kwong, Raymond, González, Arantxa, Colan, Steven D, Seidman, J.G, Seidman, Christine E, Díez, Javier

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Epigenetic repression of cardiac progenitor gene expression by Ezh2 is required for postnatal cardiac homeostasis von Delgado-Olguín, Paul, Huang, Yu, Li, Xue, Christodoulou, Danos, Seidman, Christine E, Seidman, J G, Tarakhovsky, Alexander, Bruneau, Benoit G

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Contribution of rare inherited and de novo variants in 2,871 congenital heart disease probands von Jin, Sheng Chih, Homsy, Jason, Zaidi, Samir, Lu, Qiongshi, Morton, Sarah, DePalma, Steven R, Zeng, Xue, Qi, Hongjian, Chang, Weni, Sierant, Michael C, Hung, Wei-Chien, Haider, Shozeb, Zhang, Junhui, Knight, James, Bjornson, Robert D, Castaldi, Christopher, Tikhonoa, Irina R, Bilguvar, Kaya, Mane, Shrikant M, Sanders, Stephan J, Mital, Seema, Russell, Mark W, Gaynor, J William, Deanfield, John, Giardini, Alessandro, Porter, George A, Srivastava, Deepak, Lo, Cecelia W, Shen, Yufeng, Watkins, W Scott, Yandell, Mark, Yost, H Joseph, Tristani-Firouzi, Martin, Newburger, Jane W, Roberts, Amy E, Kim, Richard, Zhao, Hongyu, Kaltman, Jonathan R, Goldmuntz, Elizabeth, Chung, Wendy K, Seidman, Jonathan G, Gelb, Bruce D, Seidman, Christine E, Lifton, Richard P, Brueckner, Martina

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Spatiotemporal Multi-Omics Mapping Generates a Molecular Atlas of the Aortic Valve and Reveals Networks Driving Disease von Schlotter, Florian, Halu, Arda, Goto, Shinji, Blaser, Mark C, Body, Simon C, Lee, Lang H, Higashi, Hideyuki, DeLaughter, Daniel M, Hutcheson, Joshua D, Vyas, Payal, Pham, Tan, Rogers, Maximillian A, Sharma, Amitabh, Seidman, Christine E, Loscalzo, Joseph, Seidman, Jonathan G, Aikawa, Masanori, Singh, Sasha A, Aikawa, Elena

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Effects of myosin variants on interacting-heads motif explain distinct hypertrophic and dilated cardiomyopathy phenotypes von Alamo, Lorenzo, Ware, James S, Pinto, Antonio, Gillilan, Richard E, Seidman, Jonathan G, Seidman, Christine E, Padrón, Raúl

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A Tension-Based Model Distinguishes Hypertrophic versus Dilated Cardiomyopathy von Davis, Jennifer, Davis, L. Craig, Correll, Robert N., Makarewich, Catherine A., Schwanekamp, Jennifer A., Moussavi-Harami, Farid, Wang, Dan, York, Allen J., Wu, Haodi, Houser, Steven R., Seidman, Christine E., Seidman, Jonathan G., Regnier, Michael, Metzger, Joseph M., Wu, Joseph C., Molkentin, Jeffery D.

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Mechanism based therapies enable personalised treatment of hypertrophic cardiomyopathy von Margara, Francesca, Psaras, Yiangos, Wang, Zhinuo Jenny, Schmid, Manuel, Doste, Ruben, Garfinkel, Amanda C., Repetti, Giuliana G., Seidman, Jonathan G., Seidman, Christine E., Rodriguez, Blanca, Toepfer, Christopher N., Bueno-Orovio, Alfonso

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Genetic and Phenotypic Landscape of Peripartum Cardiomyopathy von Goli, Rahul, Li, Jian, Brandimarto, Jeff, Levine, Lisa D., Riis, Valerie, McAfee, Quentin, DePalma, Steven, Haghighi, Alireza, Seidman, J. G., Seidman, Christine E., Jacoby, Daniel, Macones, George, Judge, Daniel P., Rana, Sarosh, Margulies, Kenneth B., Cappola, Thomas P., Alharethi, Rami, Damp, Julie, Hsich, Eileen, Elkayam, Uri, Sheppard, Richard, Alexis, Jeffrey D., Boehmer, John, Kamiya, Chizuko, Gustafsson, Finn, Damm, Peter, Ersbøll, Anne S., Goland, Sorel, Hilfiker-Kleiner, Denise, McNamara, Dennis M., Arany, Zolt

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SarcTrack von Toepfer, Christopher N, Sharma, Arun, Cicconet, Marcelo, Garfinkel, Amanda C, Mücke, Michael, Neyazi, Meraj, Willcox, Jon A L, Agarwal, Radhika, Schmid, Manuel, Rao, Jyoti, Ewoldt, Jourdan, Pourquié, Olivier, Chopra, Anant, Chen, Christopher S, Seidman, Jonathan G, Seidman, Christine E

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Titin-truncating variants affect heart function in disease cohorts and the general population von Schafer, Sebastian, de Marvao, Antonio, Adami, Eleonora, Fiedler, Lorna R, Ng, Benjamin, Khin, Ester, Rackham, Owen J L, van Heesch, Sebastiaan, Pua, Chee J, Kui, Miao, Walsh, Roddy, Tayal, Upasana, Prasad, Sanjay K, Dawes, Timothy J W, Ko, Nicole S J, Sim, David, Chan, Laura L H, Chin, Calvin W L, Mazzarotto, Francesco, Barton, Paul J, Kreuchwig, Franziska, de Kleijn, Dominique P V, Totman, Teresa, Biffi, Carlo, Tee, Nicole, Rueckert, Daniel, Schneider, Valentin, Faber, Allison, Regitz-Zagrosek, Vera, Seidman, Jonathan G, Seidman, Christine E, Linke, Wolfgang A, Kovalik, Jean-Paul, O'Regan, Declan, Ware, James S, Hubner, Norbert, Cook, Stuart A

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Genetic Basis of Hypertrophic Cardiomyopathy: From Bench to the Clinics von ALCALAI, RONNY, SEIDMAN, JONATHAN G., SEIDMAN, CHRISTINE E.

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Spectrum of somatic mitochondrial mutations in five cancers von Larman, Tatianna C, DePalma, Steven R, Hadjipanayis, Angela G, Protopopov, Alexei, Zhang, Jianhua, Gabriel, Stacey B, Chin, Lynda, Seidman, Christine E, Kucherlapati, Raju, Seidman, J. G

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Shared Genetic Causes of Cardiac Hypertrophy in Children and Adults von Morita, Hiroyuki, Rehm, Heidi L, Menesses, Andres, McDonough, Barbara, Roberts, Amy E, Kucherlapati, Raju, Towbin, Jeffrey A, Seidman, J.G, Seidman, Christine E

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Genome sequencing as a first-line genetic test in familial dilated cardiomyopathy von Minoche, Andre E., Horvat, Claire, Johnson, Renee, Gayevskiy, Velimir, Morton, Sarah U., Drew, Alexander P., Woo, Kerhan, Statham, Aaron L., Lundie, Ben, Bagnall, Richard D., Ingles, Jodie, Semsarian, Christopher, Seidman, J. G., Seidman, Christine E., Dinger, Marcel E., Cowley, Mark J., Fatkin, Diane

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Paternal-age-related de novo mutations and risk for five disorders von Taylor, Jacob L., Debost, Jean-Christophe P. G., Morton, Sarah U., Wigdor, Emilie M., Heyne, Henrike O., Lal, Dennis, Howrigan, Daniel P., Bloemendal, Alex, Larsen, Janne T., Kosmicki, Jack A., Weiner, Daniel J., Homsy, Jason, Seidman, Jonathan G., Seidman, Christine E., Agerbo, Esben, McGrath, John J., Mortensen, Preben Bo, Petersen, Liselotte, Daly, Mark J., Robinson, Elise B.

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