Obesity-induced overexpression of miR-802 impairs glucose metabolism through silencing of Hnf1b von Kornfeld, Jan-Wilhelm, Baitzel, Catherina, Könner, A. Christine, Nicholls, Hayley T., Vogt, Merly C., Herrmanns, Karolin, Scheja, Ludger, Haumaitre, Cécile, Wolf, Anna M., Knippschild, Uwe, Seibler, Jost, Cereghini, Silvia, Heeren, Joerg, Stoffel, Markus, Brüning, Jens C.

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Focal segmental glomerulosclerosis is induced by microRNA-193a and its downregulation of WT1 von Gebeshuber, Christoph A, Kornauth, Christoph, Dong, Lihua, Sierig, Ralph, Seibler, Jost, Reiss, Martina, Tauber, Stefanie, Bilban, Martin, Wang, Shijun, Kain, Renate, Böhmig, Georg A, Moeller, Marcus J, Gröne, Hermann-Josef, Englert, Christoph, Martinez, Javier, Kerjaschki, Dontscho

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Inducible and reversible gene silencing by stable integration of an shRNA-encoding lentivirus in transgenic rats von Herold, Marco J, van den Brandt, Jens, Seibler, Jost, Reichardt, Holger M

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Generation and utility of genetically humanized mouse models von Scheer, Nico, Snaith, Mike, Wolf, C. Roland, Seibler, Jost

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Quantitative prediction of human pregnane X receptor and cytochrome P450 3A4 mediated drug-drug interaction in a novel multiple humanized mouse line von Hasegawa, Maki, Kapelyukh, Yury, Tahara, Harunobu, Seibler, Jost, Rode, Anja, Krueger, Sylvia, Lee, Dongtao N, Wolf, C Roland, Scheer, Nico

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The histone 3 lysine 4 methyltransferase, Mll2, is only required briefly in development and spermatogenesis von Glaser, Stefan, Lubitz, Sandra, Loveland, Kate L, Ohbo, Kazu, Robb, Lorraine, Schwenk, Frieder, Seibler, Jost, Roellig, Daniela, Kranz, Andrea, Anastassiadis, Konstantinos, Stewart, A Francis

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Reversible gene knockdown in mice using a tight, inducible shRNA expression system von Seibler, Jost, Kleinridders, Andre, Küter-Luks, Birgit, Niehaves, Sandra, Brüning, Jens C., Schwenk, Frieder

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Polycomb group gene Ezh2 regulates mammary gland morphogenesis and maintains the luminal progenitor pool von Michalak, Ewa Malgorzata, Nacerddine, Karim, Pietersen, Alexandra, Beuger, Vincent, Pawlitzky, Inka, Cornelissen‐Steijger, Paulien, Wientjens, Ellen, Tanger, Ellen, Seibler, Jost, van Lohuizen, Maarten, Jonkers, Jos

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Rapid generation of inducible mouse mutants von Seibler, Jost, Zevnik, Branko, Küter‐Luks, Birgit, Andreas, Susanne, Kern, Heidrun, Hennek, Thomas, Rode, Anja, Heimann, Cornelia, Faust, Nicole, Kauselmann, Gunther, Schoor, Michael, Jaenisch, Rudolf, Rajewsky, Klaus, Kühn, Ralf, Schwenk, Frieder

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Single copy shRNA configuration for ubiquitous gene knockdown in mice von Seibler, Jost, Küter-Luks, Birgit, Kern, Heidrun, Streu, Sandra, Plum, Leona, Mauer, Jan, Kühn, Ralf, Brüning, Jens C., Schwenk, Frieder

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Investigation of TRPV1 loss-of-function phenotypes in transgenic shRNA expressing and knockout mice von Christoph, Thomas, Bahrenberg, Gregor, De Vry, Jean, Englberger, Werner, Erdmann, Volker A., Frech, Moritz, Kögel, Babette, Röhl, Thomas, Schiene, Klaus, Schröder, Wolfgang, Seibler, Jost, Kurreck, Jens

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Inducible transgenic rat model for diabetes mellitus based on shRNA-mediated gene knockdown von Kotnik, Katarina, Popova, Elena, Todiras, Mihail, Mori, Marcelo A, Alenina, Natalia, Seibler, Jost, Bader, Michael

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Performance of Genomic Bordering Elements at Predefined Genomic Loci von Goetze, Sandra, Baer, Alexandra, Winkelmann, Silke, Nehlsen, Kristina, Seibler, Jost, Maass, Karin, Bode, Jürgen

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Site-specific chromosomal integration in mammalian cells: highly efficient CRE recombinase-mediated cassette exchange von Feng, Yong-Qing, Seibler, Jost, Alami, Raouf, Eisen, Andrew, Westerman, Karen A, Leboulch, Philippe, Fiering, Steven, Bouhassira, Eric E

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Obesity-induced overexpression of miRNA-143 inhibits insulin-stimulated AKT activation and impairs glucose metabolism von Wunderlich, F. Thomas, Brönneke, Hella S, Brüning, Jens C, Böttger, Thomas, Seibler, Jost, Braun, Thomas, Krüger, Markus, Kashkar, Hamid, Olkkonen, Vesa M, Jordan, Sabine D, Willmes, Diana M, Merkwirth, Carsten, Redemann, Nora

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DNA Cassette Exchange in ES Cells Mediated by FLP Recombinase:  An Efficient Strategy for Repeated Modification of Tagged Loci by Marker-Free Constructs von Seibler, Jost, Schübeler, Dirk, Fiering, Steven, Groudine, Mark, Bode, Jürgen

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A high-throughput functional complementation assay for classification of BRCA1 missense variants von Bouwman, Peter, van der Gulden, Hanneke, van der Heijden, Ingrid, Drost, Rinske, Klijn, Christiaan N, Prasetyanti, Pramudita, Pieterse, Mark, Wientjens, Ellen, Seibler, Jost, Hogervorst, Frans B L, Jonkers, Jos

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Transgenic RNAi Applications in the Mouse von Seibler, Jost, Schwenk, Frieder

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Central insulin action regulates peripheral glucose and fat metabolism in mice von Koch, Linda, Wunderlich, F Thomas, Seibler, Jost, Könner, A Christine, Hampel, Brigitte, Irlenbusch, Sigrid, Brabant, Georg, Kahn, C Ronald, Schwenk, Frieder, Brüning, Jens C

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Toxicity modelling of Plk1-targeted therapies in genetically engineered mice and cultured primary mammalian cells von Raab, Monika, Kappel, Sven, Krämer, Andrea, Sanhaji, Mourad, Matthess, Yves, Kurunci-Csacsko, Elisabeth, Calzada-Wack, Julia, Rathkolb, Birgit, Rozman, Jan, Adler, Thure, Busch, Dirk H., Esposito, Irene, Fuchs, Helmut, Gailus-Durner, Valérie, Klingenspor, Martin, Wolf, Eckhard, Sänger, Nicole, Prinz, Florian, Angelis, Martin Hrabě de, Seibler, Jost, Yuan, Juping, Bergmann, Martin, Knecht, Rainald, Kreft, Bertolt, Strebhardt, Klaus

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