Integrins and cancer: regulators of cancer stemness, metastasis, and drug resistance von Seguin, Laetitia, Desgrosellier, Jay S, Weis, Sara M, Cheresh, David A

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A small-molecule P2RX7 activator promotes anti-tumor immune responses and sensitizes lung tumor to immunotherapy von Douguet, Laetitia, Janho dit Hreich, Serena, Benzaquen, Jonathan, Seguin, Laetitia, Juhel, Thierry, Dezitter, Xavier, Duranton, Christophe, Ryffel, Bernhard, Kanellopoulos, Jean, Delarasse, Cecile, Renault, Nicolas, Furman, Christophe, Homerin, Germain, Féral, Chloé, Cherfils-Vicini, Julien, Millet, Régis, Adriouch, Sahil, Ghinet, Alina, Hofman, Paul, Vouret-Craviari, Valérie

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NANOBODY® Molecule, a Giga Medical Tool in Nanodimensions von Kunz, Sarah, Durandy, Manon, Seguin, Laetitia, Feral, Chloe C

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Glut3 Addiction Is a Druggable Vulnerability for a Molecularly Defined Subpopulation of Glioblastoma von Cosset, Érika, Ilmjärv, Sten, Dutoit, Valérie, Elliott, Kathryn, von Schalscha, Tami, Camargo, Maria F., Reiss, Alexander, Moroishi, Toshiro, Seguin, Laetitia, Gomez, German, Moo, Jung-Soon, Preynat-Seauve, Olivier, Krause, Karl-Heinz, Chneiweiss, Hervé, Sarkaria, Jann N., Guan, Kun-Liang, Dietrich, Pierre-Yves, Weis, Sara M., Mischel, Paul S., Cheresh, David A.

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Galectin-3, a Druggable Vulnerability for KRAS-Addicted Cancers von Seguin, Laetitia, Camargo, Maria F, Wettersten, Hiromi I, Kato, Shumei, Desgrosellier, Jay S, von Schalscha, Tami, Elliott, Kathryn C, Cosset, Erika, Lesperance, Jacqueline, Weis, Sara M, Cheresh, David A

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Macropinocytosis requires Gal-3 in a subset of patient-derived glioblastoma stem cells von Seguin, Laetitia, Odouard, Soline, Corlazzoli, Francesca, Haddad, Sarah Al, Moindrot, Laurine, Calvo Tardón, Marta, Yebra, Mayra, Koval, Alexey, Marinari, Eliana, Bes, Viviane, Guérin, Alexandre, Allard, Mathilde, Ilmjärv, Sten, Katanaev, Vladimir L., Walker, Paul R., Krause, Karl-Heinz, Dutoit, Valérie, Sarkaria, Jann N., Dietrich, Pierre-Yves, Cosset, Érika

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APC(cdh1) mediates degradation of the oncogenic Rho-GEF Ect2 after mitosis von Liot, Caroline, Seguin, Laetitia, Siret, Aurélie, Crouin, Catherine, Schmidt, Susanne, Bertoglio, Jacques

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CUX1 and E2F1 Regulate Coordinated Expression of the Mitotic Complex Genes Ect2, MgcRacGAP, and MKLP1 in S Phase von Seguin, Laetitia, Liot, Caroline, Mzali, Rym, Harada, Ryoko, Siret, Aurelie, Nepveu, Alain, Bertoglio, Jacques

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Lung Adenocarcinoma Tumor Origin: A Guide for Personalized Medicine von Seguin, Laetitia, Durandy, Manon, Feral, Chloe C

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Phosphoregulation of MgcRacGAP in mitosis involves Aurora B and Cdk1 protein kinases and the PP2A phosphatase von Touré, Aminata, Mzali, Rym, Liot, Caroline, Seguin, Laetitia, Morin, Laurence, Crouin, Catherine, Chen-Yang, Ilin, Tsay, Yeou-Guang, Dorseuil, Olivier, Gacon, Gérard, Bertoglio, Jacques

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Functional transfer of integrin co-receptor CD98hc by small extracellular vesicles improves wound healing in vivo von Tissot, Floriane S, Estrach, Soline, Seguin, Laetitia, Cailleteau, Laurence, Levy, Ayelet, Aberdam, Daniel, Féral, Chloé C

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Integrin αvβ3 Drives Slug Activation and Stemness in the Pregnant and Neoplastic Mammary Gland von Desgrosellier, Jay S., Lesperance, Jacqueline, Seguin, Laetitia, Gozo, Maricel, Kato, Shumei, Franovic, Aleksandra, Yebra, Mayra, Shattil, Sanford J., Cheresh, David A.

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A regulatory circuit controlled by extranuclear and nuclear retinoic acid receptor α determines T cell activation and function von Larange, Alexandre, Takazawa, Ikuo, Kakugawa, Kiyokazu, Thiault, Nicolas, Ngoi, SooMun, Olive, Meagan E., Iwaya, Hitoshi, Seguin, Laetitia, Vicente-Suarez, Ildefonso, Becart, Stephane, Verstichel, Greet, Balancio, Ann, Altman, Amnon, Chang, John T., Taniuchi, Ichiro, Lillemeier, Bjorn, Kronenberg, Mitchell, Myers, Samuel A., Cheroutre, Hilde

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Glioblastomas require integrin αvβ3/PAK4 signaling to escape senescence von Franovic, Aleksandra, Elliott, Kathryn C, Seguin, Laetitia, Camargo, M Fernanda, Weis, Sara M, Cheresh, David A

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Personalized medicine: exploiting druggable vulnerabilities for KRAS-driven lung cancer von Seguin, Laetitia, Féral, Chloé

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Kinase-independent role for CRAF-driving tumour radioresistance via CHK2 von Advani, Sunil J., Camargo, Maria Fernanda, Seguin, Laetitia, Mielgo, Ainhoa, Anand, Sudarshan, Hicks, Angel M., Aguilera, Joseph, Franovic, Aleksandra, Weis, Sara M., Cheresh, David A.

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Dermal Fibroblast SLC3A2 Deficiency Leads to Premature Aging and Loss of Epithelial Homeostasis von Tissot, Floriane S., Estrach, Soline, Boulter, Etienne, Cailleteau, Laurence, Tosello, Lionel, Seguin, Laetitia, Pisano, Sabrina, Audebert, Stéphane, Croce, Olivier, Féral, Chloé C.

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Abstract 3966: Targeting integrin αvβ3-expressing cancer stem cells to manipulate tumor-associated macrophages von Wettersten, Hiromi I., Minami, Toshiyuki, Kaneda, Megan M., Seguin, Laetitia, Varner, Judith A., Weis, Sara M., Cheresh, David A.

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APCcdh1 Mediates Degradation of the Oncogenic Rho-GEF Ect2 after Mitosis von Liot, Caroline, Seguin, Laetitia, Siret, Aurélie, Crouin, Catherine, Schmidt, Susanne, Bertoglio, Jacques

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A MEK-independent role for CRAF in mitosis and tumor progression von Mielgo, Ainhoa, Seguin, Laetitia, Huang, Miller, Camargo, Maria Fernanda, Anand, Sudarshan, Franovic, Aleksandra, Weis, Sara M, Advani, Sunil J, Murphy, Eric A, Cheresh, David A

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