Catalytic Control in the EGF Receptor and Its Connection to General Kinase Regulatory Mechanisms von Jura, Natalia, Zhang, Xuewu, Endres, Nicholas F., Seeliger, Markus A., Schindler, Thomas, Kuriyan, John

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All the mutations that are fit to die von Gebauer, Emma, Seeliger, Markus A.

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Protein Flexibility and Dissociation Pathway Differentiation Can Explain Onset of Resistance Mutations in Kinases von Shekhar, Mrinal, Smith, Zachary, Seeliger, Markus A., Tiwary, Pratyush

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Targeting Conformational Plasticity of Protein Kinases von Tong, Michael, Seeliger, Markus A

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Calculating Protein–Ligand Residence Times through State Predictive Information Bottleneck Based Enhanced Sampling von Lee, Suemin, Wang, Dedi, Seeliger, Markus A., Tiwary, Pratyush

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Allo-targeting of the kinase domain: Insights from in silico studies and comparison with experiments von Lee, Ji Young, Gebauer, Emma, Seeliger, Markus A., Bahar, Ivet

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Editorial overview: Molecular determinants, mechanisms, and state-of-the-art approaches in allostery von Berezovsky, Igor N., Seeliger, Markus A.

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Structural mechanism of a drug-binding process involving a large conformational change of the protein target von Ayaz, Pelin, Lyczek, Agatha, Paung, YiTing, Mingione, Victoria R., Iacob, Roxana E., de Waal, Parker W., Engen, John R., Seeliger, Markus A., Shan, Yibing, Shaw, David E.

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A dynamically coupled allosteric network underlies binding cooperativity in Src kinase von Foda, Zachariah H., Shan, Yibing, Kim, Eric T., Shaw, David E., Seeliger, Markus A.

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Activation of tyrosine kinases by mutation of the gatekeeper threonine von Kuriyan, John, Daley, George Q, Azam, Mohammad, Seeliger, Markus A, Gray, Nathanael S

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Probing conformational dynamics to understand kinase inhibition von Outhwaite, Ian R, Seeliger, Markus A

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How Does a Drug Molecule Find Its Target Binding Site? von Shan, Yibing, Kim, Eric T, Eastwood, Michael P, Dror, Ron O, Seeliger, Markus A, Shaw, David E

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Anti-diabetic activity of insulin-degrading enzyme inhibitors mediated by multiple hormones von Maianti, Juan Pablo, McFedries, Amanda, Foda, Zachariah H., Kleiner, Ralph E., Du, Xiu Quan, Leissring, Malcolm A., Tang, Wei-Jen, Charron, Maureen J., Seeliger, Markus A., Saghatelian, Alan, Liu, David R.

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Inhibiting ACK1-mediated phosphorylation of C-terminal Src kinase counteracts prostate cancer immune checkpoint blockade resistance von Sridaran, Dhivya, Chouhan, Surbhi, Mahajan, Kiran, Renganathan, Arun, Weimholt, Cody, Bhagwat, Shambhavi, Reimers, Melissa, Kim, Eric H., Thakur, Manish K., Saeed, Muhammad A., Pachynski, Russell K., Seeliger, Markus A., Miller, W. Todd, Feng, Felix Y., Mahajan, Nupam P.

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A conserved mechanism of DEAD-box ATPase activation by nucleoporins and InsP6 in mRNA export von Montpetit, Ben, Thomsen, Nathan D., Helmke, Kara J., Seeliger, Markus A., Berger, James M., Weis, Karsten

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Survey of solution dynamics in Src kinase reveals allosteric cross talk between the ligand binding and regulatory sites von Tong, Michael, Pelton, Jeff G., Gill, Michelle L., Zhang, Weibing, Picart, Francis, Seeliger, Markus A.

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What makes a kinase promiscuous for inhibitors? von Hanson, Sonya M., Georghiou, George, Thakur, Manish K., Miller, W. Todd, Rest, Joshua S., Chodera, John D., Seeliger, Markus A.

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conserved protonation-dependent switch controls drug binding in the Abl kinase von Shan, Yibing, Seeliger, Markus A, Eastwood, Michael P, Frank, Filipp, Xu, Huafeng, Jensen, Morten Ø, Dror, Ron O, Kuriyan, John, Shaw, David E

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Biochemical Studies of Systemic Lupus Erythematosus-Associated Mutations in Nonreceptor Tyrosine Kinases Ack1 and Brk von Kan, Yagmur, Paung, YiTing, Kim, Yunyoung, Seeliger, Markus A., Miller, W. Todd

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A Novel In Vitro CypD-Mediated p53 Aggregation Assay Suggests a Model for Mitochondrial Permeability Transition by Chaperone Systems von Lebedev, Ivan, Nemajerova, Alice, Foda, Zachariah H., Kornaj, Maja, Tong, Michael, Moll, Ute M., Seeliger, Markus A.

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