Crystal structure of a heterodimeric ABC transporter in its inward-facing conformation von Hohl, Michael, Briand, Christophe, Grütter, Markus G, Seeger, Markus A

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Critical discussion on drug efflux in Mycobacterium tuberculosis von Remm, Sille, Earp, Jennifer C, Dick, Thomas, Dartois, Véronique, Seeger, Markus A

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Structural basis for pH-dependent retrieval of ER proteins from the Golgi by the KDEL receptor von Bräuer, Philipp, Parker, Joanne L, Gerondopoulos, Andreas, Zimmermann, Iwan, Seeger, Markus A, Barr, Francis A, Newstead, Simon

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Selection, biophysical and structural analysis of synthetic nanobodies that effectively neutralize SARS-CoV-2 von Custódio, Tânia F., Das, Hrishikesh, Sheward, Daniel J., Hanke, Leo, Pazicky, Samuel, Pieprzyk, Joanna, Sorgenfrei, Michèle, Schroer, Martin A., Gruzinov, Andrey Yu, Jeffries, Cy M., Graewert, Melissa A., Svergun, Dmitri I., Dobrev, Nikolay, Remans, Kim, Seeger, Markus A., McInerney, Gerald M., Murrell, Ben, Hällberg, B. Martin, Löw, Christian

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Synthetic single domain antibodies for the conformational trapping of membrane proteins von Zimmermann, Iwan, Egloff, Pascal, Hutter, Cedric Aj, Arnold, Fabian M, Stohler, Peter, Bocquet, Nicolas, Hug, Melanie N, Huber, Sylwia, Siegrist, Martin, Hetemann, Lisa, Gera, Jennifer, Gmür, Samira, Spies, Peter, Gygax, Daniel, Geertsma, Eric R, Dawson, Roger Jp, Seeger, Markus A

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Transport of drugs by the multidrug transporter AcrB involves an access and a deep binding pocket that are separated by a switch-loop von Eicher, Thomas, Cha, Hi-jea, Seeger, Markus A, Brandstätter, Lorenz, El-Delik, Jasmin, Bohnert, Jürgen A, Kern, Winfried V, Verrey, François, Grütter, Markus G, Diederichs, Kay, Pos, Klaas M

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Structural basis for allosteric cross-talk between the asymmetric nucleotide binding sites of a heterodimeric ABC exporter von Hohl, Michael, Hürlimann, Lea M., Böhm, Simon, Schöppe, Jendrik, Grütter, Markus G., Bordignon, Enrica, Seeger, Markus A.

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A synthetic nanobody targeting RBD protects hamsters from SARS-CoV-2 infection von Li, Tingting, Cai, Hongmin, Yao, Hebang, Zhou, Bingjie, Zhang, Ning, van Vlissingen, Martje Fentener, Kuiken, Thijs, Han, Wenyu, GeurtsvanKessel, Corine H., Gong, Yuhuan, Zhao, Yapei, Shen, Quan, Qin, Wenming, Tian, Xiao-Xu, Peng, Chao, Lai, Yanling, Wang, Yanxing, Hutter, Cedric A. J., Kuo, Shu-Ming, Bao, Juan, Liu, Caixuan, Wang, Yifan, Richard, Audrey S., Raoul, Hervé, Lan, Jiaming, Seeger, Markus A., Cong, Yao, Rockx, Barry, Wong, Gary, Bi, Yuhai, Lavillette, Dimitri, Li, Dianfan

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The ABC exporter IrtAB imports and reduces mycobacterial siderophores von Arnold, Fabian M., Weber, Miriam S., Gonda, Imre, Gallenito, Marc J., Adenau, Sophia, Egloff, Pascal, Zimmermann, Iwan, Hutter, Cedric A. J., Hürlimann, Lea M., Peters, Eike E., Piel, Jörn, Meloni, Gabriele, Medalia, Ohad, Seeger, Markus A.

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Interdomain-linkers control conformational transitions in the SLC23 elevator transporter UraA von Kuhn, Benedikt T., Zöller, Jonathan, Zimmermann, Iwan, Gemeinhardt, Tim, Özkul, Dogukan H., Langer, Julian D., Seeger, Markus A., Geertsma, Eric R.

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Allosteric modulation of LRRC8 channels by targeting their cytoplasmic domains von Deneka, Dawid, Rutz, Sonja, Hutter, Cedric A. J., Seeger, Markus A., Sawicka, Marta, Dutzler, Raimund

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The extracellular gate shapes the energy profile of an ABC exporter von Hutter, Cedric A. J., Timachi, M. Hadi, Hürlimann, Lea M., Zimmermann, Iwan, Egloff, Pascal, Göddeke, Hendrik, Kucher, Svetlana, Štefanić, Saša, Karttunen, Mikko, Schäfer, Lars V., Bordignon, Enrica, Seeger, Markus A.

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Doa10/MARCH6 architecture interconnects E3 ligase activity with lipid-binding transmembrane channel to regulate SQLE von Botsch, J. Josephine, Junker, Roswitha, Sorgenfrei, Michèle, Ogger, Patricia P., Stier, Luca, von Gronau, Susanne, Murray, Peter J., Seeger, Markus A., Schulman, Brenda A., Bräuning, Bastian

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Coupling of remote alternating-access transport mechanisms for protons and substrates in the multidrug efflux pump AcrB von Eicher, Thomas, Seeger, Markus A, Anselmi, Claudio, Zhou, Wenchang, Brandstätter, Lorenz, Verrey, François, Diederichs, Kay, Faraldo-Gómez, José D, Pos, Klaas M

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Structural insights into Legionella RidL-Vps29 retromer subunit interaction reveal displacement of the regulator TBC1D5 von Bärlocher, Kevin, Hutter, Cedric A. J., Swart, A. Leoni, Steiner, Bernhard, Welin, Amanda, Hohl, Michael, Letourneur, François, Seeger, Markus A., Hilbi, Hubert

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Structural basis for triacylglyceride extraction from mycobacterial inner membrane by MFS transporter Rv1410 von Remm, Sille, De Vecchis, Dario, Schöppe, Jendrik, Hutter, Cedric A. J., Gonda, Imre, Hohl, Michael, Newstead, Simon, Schäfer, Lars V., Seeger, Markus A.

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Structural Asymmetry of AcrB Trimer Suggests a Peristaltic Pump Mechanism von Seeger, Markus A, Schiefner, André, Eicher, Thomas, Verrey, François, Diederichs, Kay, Pos, Klaas M

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Molecular basis of multidrug transport by ABC transporters von Seeger, Markus A., van Veen, Hendrik W.

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Cryo-EM structures of a LptDE transporter in complex with Pro-macrobodies offer insight into lipopolysaccharide translocation von Botte, Mathieu, Ni, Dongchun, Schenck, Stephan, Zimmermann, Iwan, Chami, Mohamed, Bocquet, Nicolas, Egloff, Pascal, Bucher, Denis, Trabuco, Matilde, Cheng, Robert K. Y., Brunner, Janine D., Seeger, Markus A., Stahlberg, Henning, Hennig, Michael

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Atomistic Mechanism of Large-Scale Conformational Transition in a Heterodimeric ABC Exporter von Göddeke, Hendrik, Timachi, M. Hadi, Hutter, Cedric A. J, Galazzo, Laura, Seeger, Markus A, Karttunen, Mikko, Bordignon, Enrica, Schäfer, Lars V

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