A scalable high-throughput targeted next-generation sequencing assay for comprehensive genomic profiling of solid tumors von Conroy, Jeffrey M, Pabla, Sarabjot, Glenn, Sean T, Seager, R J, Van Roey, Erik, Gao, Shuang, Burgher, Blake, Andreas, Jonathan, Giamo, Vincent, Mallon, Melissa, Lee, Yong Hee, DePietro, Paul, Nesline, Mary, Wang, Yirong, Lenzo, Felicia L, Klein, Roger, Zhang, Shengle

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Cancer/testis antigen expression and co-expression patterns in gastroesophageal adenocarcinoma von Kalvapudi, Sukumar, Pachimatla, Akhil Goud, Seager, R. J., Conroy, Jeffrey, Pabla, Sarabjot, Mukherjee, Sarbajit

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Cancer testis antigen burden (CTAB): a novel biomarker of tumor-associated antigens in lung cancer von Seager, R J, Senosain, Maria-Fernanda, Van Roey, Erik, Gao, Shuang, DePietro, Paul, Nesline, Mary K, Dash, Durga Prasad, Zhang, Shengle, Ko, Heidi, Hastings, Stephanie B, Strickland, Kyle C, Previs, Rebecca A, Jensen, Taylor J, Eisenberg, Marcia, Caveney, Brian J, Severson, Eric A, Ramkissoon, Shakti, Conroy, Jeffrey M, Pabla, Sarabjot

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Pre-radiation Nivolumab plus ipilimumab in patients with newly diagnosed high-grade gliomas von Kesari, Santosh, Wojcinski, Alexandre, Pabla, Sarabjot, Seager, R. J., Gill, Jaya M., Carrillo, Jose A., Wagle, Naveed, Park, David J., Nguyen, Minhdan, Truong, Judy, Takasumi, Yuki, Chaiken, Lisa, Chang, Shu-Ching, Barkhoudarian, Garni, Kelly, Daniel F., Juarez, Tiffany M.

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Integration of tumor inflammation, cell proliferation, and traditional biomarkers improves prediction of immunotherapy resistance and response von Pabla, Sarabjot, Seager, R J, Van Roey, Erik, Gao, Shuang, Hoefer, Carrie, Nesline, Mary K, DePietro, Paul, Burgher, Blake, Andreas, Jonathan, Giamo, Vincent, Wang, Yirong, Lenzo, Felicia L, Schoenborn, Margot, Zhang, Shengle, Klein, Roger, Glenn, Sean T, Conroy, Jeffrey M

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Comprehensive Assessment of Immune Phenotype and Its Effects on Survival Outcomes in HER2-Low versus HER2-Zero Breast Cancer von Ko, Heidi Chwan, Seager, R J, Pabla, Sarabjot, Senosain, Maria-Fernanda, Van Roey, Erik, Gao, Shuang, Strickland, Kyle C, Previs, Rebecca Ann, Green, Michelle F, Cooper, Maureen, Nesline, Mary K, Hastings, Stephanie B, Amoah, Kobina Agyaful, Zhang, Shengle, Conroy, Jeffrey M, Jensen, Taylor J, Eisenberg, Marcia, Caveney, Brian, Severson, Eric A, Ramkissoon, Shakti, Gandhi, Shipra

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Solid dissolution in a fluid solvent is characterized by the interplay of surface area-dependent diffusion and physical fragmentation von Seager, R. J., Acevedo, Andrew J., Spill, Fabian, Zaman, Muhammad H.

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184 Distinct immunotherapy immune response phenotypes in non-small cell lung cancer present with unique genomic alteration profiles von Wallen, Zachary D, Seager, RJ, Pabla, Sarabjot, Nesline, Mary K, Roey, Erik Van, Gao, Shuang, Senosain, Maria-Fernanda, Hastings, Stephanie B, Strickland, Kyle C, Previs, Rebecca A, Zhang, Shengle, Conroy, Jeffrey M, Jensen, Taylor J, Eisenberg, Marcia, Caveney, Brian, Reddy, Prasanth, Severson, Eric A, Ramkissoon, Shakti

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77 Prevalence of secondary immunotherapeutic targets in the absence of established immune biomarkers in solid tumors von DePietro, Paul, Nesline, Mary, Lee, Yong Hee, Seager, RJ, Roey, Erik Van, Gao, Shuang, Giamo, Vincent, Burgher, Blake, Glenn, Sean, Zhang, Shengle, Klein, Roger, Pabla, Sarabjot, Conroy, Jeffrey

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80 Cancer testis antigen burden: A novel predictive biomarker for immunotherapy in solid tumors von Pabla, Sarabjot, Seager, RJ, Lee, Yong Hee, Roey, Erik Van, Gao, Shuang, Giamo, Vincent, Burgher, Blake, DePietro, Paul, Nesline, Mary, Glenn, Sean, Zhang, Shengle, Conroy, Jeffrey

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70 Novel immunotherapeutic targets in cancer of unknown primary (CUP) von Nesline, Mary, DePietro, Paul, Lee, Yong Hee, Bliss, Zachery, Seager, RJ, Roey, Erik Van, Gao, Shuang, Giamo, Vincent, Burgher, Blake, Glenn, Sean, Zhang, Shengle, Pabla, Sarabjot, Klein, Roger, Conroy, Jeffrey

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Integrated in silico and 3D in vitro model of macrophage migration in response to physical and chemical factors in the tumor microenvironment von Lee, Sharon Wei Ling, Seager, R J, Litvak, Felix, Spill, Fabian, Sieow, Je Lin, Leong, Penny Hweixian, Kumar, Dillip, Tan, Alrina Shin Min, Wong, Siew Cheng, Adriani, Giulia, Zaman, Muhammad Hamid, Kamm, and Roger D

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64 Cancer testis antigen co-expression landscape in solid tumors von Seager, RJ, Roey, Erik Van, Gao, Shuang, Andreas, Jonathan, Giamo, Vincent, Burgher, Blake, Lenzo, Felicia, Nesline, Mary, DePietro, Paul, Wang, Yirong, Glenn, Sean, Zhang, Shengle, Conroy, Jeffrey, Pabla, Sarabjot

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Tumor Inflammation, Obesity, and Proliferative Status as Biomarkers in Gastroesophageal Adenocarcinoma von Mukherjee, Sarbajit, Seager, R J, Lee, Yong Hee, Conroy, Jeffrey M, Kalinski, Pawel, Pabla, Sarabjot

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BIOM-03. COMPREHENSIVE GENOMIC AND IMMUNE PROFILING OF NON-SMALL CELL LUNG CANCER BRAIN METASTASES REVEALS LOW TUMOR INFLAMMATION AND ELEVATED CANCER TESTIS ANTIGEN BURDEN von Seager, R J, Pabla, Sarabjot, Achyut, B R, Nesline, Mary, Kannan, Geoffrey, Chenn, Anjen, Zhang, Shengle, Klein, Roger, Conroy, Jeffrey, Sausen, Mark, Saini, Kamal, Jensen, Taylor, Reddy, Prasanth, Severson, Eric, Ramkissoon, Shakti

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15 Integration of multiple immune-associated biomarkers facilitates classification of solid tumors by primary immune escape mode and prediction of patient outcomes von Seager, R J, Maria-Fernanda Senosain, Erik Van Roey, Gao, Shuang, Nesline, Mary, Conroy, Jeffrey, Pabla, Sarabjot

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Environmental health challenges in South Africa: policy lessons from case studies von Thomas, E.P, Seager, J.R, Mathee, A

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An evaluation of an education programme on HIV infection using puppetry and street theatre von Skinner, D., Metcalf, C. A., Seager, J. R., De Swardt, J. S., Laubscher, J. A.

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Dynamic interplay between tumour, stroma and immune system can drive or prevent tumour progression von Seager, R J, Hajal, Cynthia, Spill, Fabian, Kamm, Roger D, Zaman, Muhammad H

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Development and testing of a 25-item patient satisfaction scale for black South African diabetic outpatients von Westaway, M S, Rheeder, P, van Zyl, D G, Seager, J R

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