Misfolded proteins bind and activate death receptor 5 to trigger apoptosis during unresolved endoplasmic reticulum stress von Lam, Mable, Marsters, Scot A, Ashkenazi, Avi, Walter, Peter

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Caspase-mediated cleavage of IRE1 controls apoptotic cell commitment during endoplasmic reticulum stress von Shemorry, Anna, Harnoss, Jonathan M, Guttman, Ofer, Marsters, Scot A, Kőműves, László G, Lawrence, David A, Ashkenazi, Avi

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Coordination between Two Branches of the Unfolded Protein Response Determines Apoptotic Cell Fate von Chang, Tsun-Kai, Lawrence, David A., Lu, Min, Tan, Jenille, Harnoss, Jonathan M., Marsters, Scot A., Liu, Peter, Sandoval, Wendy, Martin, Scott E., Ashkenazi, Avi

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Control of TRAIL-Induced Apoptosis by a Family of Signaling and Decoy Receptors von Sheridan, James P., Marsters, Scot A., Pitti, Robert M., Gurney, Austin, Skubatch, Maya, Baldwin, Daryl, Ramakrishnan, Lakshmi, Gray, Christa L., Baker, Kevin, Wood, William I., Goddard, Audrey D., Godowski, Paul, Ashkenazi, Avi

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Isotype-Dependent Inhibition of Tumor Growth In Vivo by Monoclonal Antibodies to Death Receptor 4 von Chuntharapai, Anan, Dodge, Kelly, Grimmer, Katharine, Schroeder, Kurt, Marsters, Scot A, Koeppen, Hartmut, Ashkenazi, Avi, Kim, K. Jin

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IRE1α Disruption in Triple-Negative Breast Cancer Cooperates with Antiangiogenic Therapy by Reversing ER Stress Adaptation and Remodeling the Tumor Microenvironment von Harnoss, Jonathan M, Le Thomas, Adrien, Reichelt, Mike, Guttman, Ofer, Wu, Thomas D, Marsters, Scot A, Shemorry, Anna, Lawrence, David A, Kan, David, Segal, Ehud, Merchant, Mark, Totpal, Klara, Crocker, Lisa M, Mesh, Kathryn, Dohse, Monika, Solon, Margaret, Modrusan, Zora, Rudolph, Joachim, Koeppen, Hartmut, Walter, Peter, Ashkenazi, Avi

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Identification of a receptor for BLyS demonstrates a crucial role in humoral immunity von Yan, Minhong, Marsters, Scot A., Grewal, Iqbal S., Wang, Hua, Ashkenazi, Avi, Dixit, Vishva M.

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Disruption of IRE1α through its kinase domain attenuates multiple myeloma von Harnoss, Jonathan M., Le Thomas, Adrien, Shemorry, Anna, Marsters, Scot A., Lawrence, David A., Lu, Min, Chen, Yung-Chia Ariel, Qing, Jing, Totpal, Klara, Kan, David, Segal, Ehud, Merchant, Mark, Reichelt, Mike, Wallweber, Heidi Ackerly, Wang, Weiru, Clark, Kevin, Kaufman, Susan, Beresini, Maureen H., Laing, Steven T., Sandoval, Wendy, Lorenzo, Maria, Wu, Jiansheng, Ly, Justin, De Bruyn, Tom, Heidersbach, Amy, Haley, Benjamin, Gogineni, Alvin, Weimer, Robby M., Lee, Dong, Braun, Marie-Gabrielle, Rudolph, Joachim, VanWyngarden, Michael J., Sherbenou, Daniel W., Gomez-Bougie, Patricia, Amiot, Martine, Acosta-Alvear, Diego, Walter, Peter, Ashkenazi, Avi

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Engineering an APRIL-specific B Cell Maturation Antigen von Patel, Darshana R., Wallweber, Heidi J.A., Yin, JianPing, Shriver, Stephanie K., Marsters, Scot A., Gordon, Nathaniel C., Starovasnik, Melissa A., Kelley, Robert F.

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ATF6 Promotes Colorectal Cancer Growth and Stemness by Regulating the Wnt Pathway von Rodvold, Jeffrey J, Grimmer, Matthew, Ruiz, Karen, Marsters, Scot A, Oikonomidi, Ioanna, Tan-Aristy, Eileen, Pham, Victoria C, Sarkar, Tamal, Harnoss, Jonathan M, Shatz-Binder, Whitney, Modrusan, Zora D, Wu, Thomas D, Lill, Jennie R, Villemure, Elisia, Rudolph, Joachim, de Sousa E Melo, Felipe, Ashkenazi, Avi

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Safety and antitumor activity of recombinant soluble Apo2 ligand von Ashkenazi, A, Pai, R C, Fong, S, Leung, S, Lawrence, D A, Marsters, S A, Blackie, C, Chang, L, McMurtrey, A E, Hebert, A, DeForge, L, Koumenis, I L, Lewis, D, Harris, L, Bussiere, J, Koeppen, H, Shahrokh, Z, Schwall, R H

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Interaction of the TNF homologues BLyS and APRIL with the TNF receptor homologues BCMA and TACI von Marsters, Scot A, Yan, Minhong, Pitti, Robert M, Haas, Philip E, Dixit, Vishva M, Ashkenazi, Avi

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Induction of Apoptosis by Apo-2 Ligand, a New Member of the Tumor Necrosis Factor Cytokine Family von Pitti, R M, Marsters, S A, Ruppert, S, Donahue, C J, Moore, A, Ashkenazi, A

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Antitherapeutic antibody-mediated hepatotoxicity of recombinant human Apo2L/TRAIL in the cynomolgus monkey von Zuch de Zafra, Christina L, Ashkenazi, Avi, Darbonne, Walter C, Cheu, Melissa, Totpal, Klara, Ortega, Shirley, Flores, Heather, Walker, Mark D, Kabakoff, Bruce, Lum, Bert L, Mounho-Zamora, Barbara J, Marsters, Scot A, Dybdal, Noël O

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TACI-ligand interactions are required for T cell activation and collagen-induced arthritis in mice von Wang, Hua, Marsters, Scot A., Baker, Thad, Chan, Betty, Lee, Wyne P., Fu, Ling, Tumas, Daniel, Yan, Minhong, Dixit, Vishva M., Ashkenazi, Avi, Grewal, Iqbal S.

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Blocking of HIV-1 Infectivity by a Soluble, Secreted Form of the CD4 Antigen von Smith, Douglas H., Byrn, Randal A., Marsters, Scot A., Gregory, Timothy, Groopman, Jerome E., Capon, Daniel J.

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Activation of the Proapoptotic Death Receptor DR5 by Oligomeric Peptide and Antibody Agonists von Li, Bing, Russell, Stephen J., Compaan, Deanne M., Totpal, Klara, Marsters, Scot A., Ashkenazi, Avi, Cochran, Andrea G., Hymowitz, Sarah G., Sidhu, Sachdev S.

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Identification of a ligand for the death-domain-containing receptor Apo3 von Marsters, Scot A., Sheridan, James P., Pitti, Robert M., Brush, Jennifer, Goddard, Audrey, Ashkenazi, Avi

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Activation of apoptosis by Apo-2 ligand is independent of FADD but blocked by CrmA von Marsters, Scot A., Pitti, Robert M., Donahue, Christopher J., Ruppert, Siegfried, Bauer, Kenneth D., Ashkenazi, Avi

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A single amino-acid difference confers major pharmacological variation between human and rodent 5-HT1B receptors von Oksenberg, Donna, Marsters, Scot A., O'Dowd, Brian F., Jin, Hui, Havlik, Sona, Peroutka, Stephen J., Ashkenazi, Avi

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