Preclinical Efficacy of the Novel Monocarboxylate Transporter 1 Inhibitor BAY-8002 and Associated Markers of Resistance von Quanz, Maria, Bender, Eckhard, Kopitz, Charlotte, Grünewald, Sylvia, Schlicker, Andreas, Schwede, Wolfgang, Eheim, Ashley, Toschi, Luisella, Neuhaus, Roland, Richter, Carmen, Toedling, Joern, Merz, Claudia, Lesche, Ralf, Kamburov, Atanas, Siebeneicher, Holger, Bauser, Marcus, Hägebarth, Andrea

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Discovery of Vilaprisan (BAY 1002670): A Highly Potent and Selective Progesterone Receptor Modulator Optimized for Gynecologic Therapies von Möller, Carsten, Bone, Wilhelm, Cleve, Arwed, Klar, Ulrich, Rotgeri, Andrea, Rottmann, Antje, Schultze‐Mosgau, Marcus‐Hillert, Wagenfeld, Andrea, Schwede, Wolfgang

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Identification of the Highly Active, Species Cross-Reactive Complex I Inhibitor BAY-179 von Mowat, Jeffrey, Ehrmann, Alexander H. M, Christian, Sven, Sperl, Carolyn, Menz, Stephan, Günther, Judith, Hillig, Roman C, Bauser, Marcus, Schwede, Wolfgang

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Total Synthesis and Antitumor Activity of ZK-EPO: The First Fully Synthetic Epothilone in Clinical Development von Klar, Ulrich, Buchmann, Bernd, Schwede, Wolfgang, Skuballa, Werner, Hoffmann, Jens, Lichtner, Rosemarie B.

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Synthesis and Biological Activity of a Novel, Highly Potent Progesterone Receptor Antagonist von Fuhrmann, Ulrike, Hess-Stumpp, Holger, Cleve, Arwed, Neef, Günter, Schwede, Wolfgang, Hoffmann, Jens, Fritzemeier, Karl-Heinrich, Chwalisz, Kristof

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BAY 1002670: a novel, highly potent and selective progesterone receptor modulator for gynaecological therapies von Wagenfeld, Andrea, Bone, Wilhelm, Schwede, Wolfgang, Fritsch, Martin, Fischer, Oliver M., Moeller, Carsten

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Abstract 3248: Identification and optimization of a highly active, cross reactive Complex-1 inhibitor von Mowat, Jeffrey, Christian, Sven, Sperl, Carolyn, Ehrmann, Alexander, Menz, Stephan, Guenther, Judith, Hillig, Roman, Bauser, Marcus, Haegebarth, Andrea, Schwede, Wolfgang

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Abstract 1126: Differential effects of metformin and phenformin vs. other complex 1 inhibitors in vitro and in vivo von Algire, Carolyn, Ehrmann, Alexander, Christian, Sven, Neuhaus, Roland, Menz, Stephan, Schwede, Wolfgang, Haerter, Michael, Haegebarth, Andrea

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Front Cover: Discovery of Vilaprisan (BAY 1002670): A Highly Potent and Selective Progesterone Receptor Modulator Optimized for Gynecologic Therapies (ChemMedChem 21/2018) von Möller, Carsten, Bone, Wilhelm, Cleve, Arwed, Klar, Ulrich, Rotgeri, Andrea, Rottmann, Antje, Schultze‐Mosgau, Marcus‐Hillert, Wagenfeld, Andrea, Schwede, Wolfgang

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Abstract 223: Comparison of human-specific versus cross-reactive Complex I inhibitor for in vivo tumor efficacy von Christian, Sven, Algire, Carolyn, Schwede, Wolfgang, Mowat, Jeffrey S., Ehrmann, Alexander, Menz, Stephan, Bauser, Marcus, Haegebarth, Andrea

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Abstract 4989: 3D spheroid screen yields SCD1 pathway inhibitors for the treatment of cancer von Gruenewald, Sylvia, Sperl, Carolyn, Steigemann, Patrick, Walter, Alexander, Zacharias, Sylvia, Eberspaecher, Uwe, Neuhaus, Roland, Zorn, Ludwig, Schwede, Wolfgang, Thede, Kai, Christian, Sven

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Improved Cellular Pharmacokinetics and Pharmacodynamics Underlie the Wide Anticancer Activity of Sagopilone von HOFFMANN, Jens, VILALE, Ilio, PANARETAKIS, Theocharis, SIEMEISTER, Gerhard, LAGE, Hermann, NANTY, Lisa, HAMMER, Stefanie, MITTELSTAEDT, Kevin, WINSEL, Sebastian, ESCHENBRENNER, Julia, CASTEDO, Maria, DEMARCHE, Carine, BUCHMANN, Bernd, KLAR, Ulrich, KROEMER, Guido, GALLUZZI, Lorenzo, SCHWEDE, Wolfgang, SENOVILLA, Laura, SKUBALLA, Werner, VIVET, Sonia, LICHTNER, Rosemarie B, VICENCIO, José M

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Abstract 317: 3D high-content screening for the identification of compounds that target cells in dormant tumor spheroid regions von Wenzel, Carsten, Christian, Sven, Algire, Carolyn, Schwede, Wolfgang, Neuhaus, Roland, Guenther, Judith, Liu, Ningshu, Raese, Sebastian, Parczyk, Karsten, Prechtl, Stefan, Steigemann, Patrick

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Abstract 2682: Small molecule targeting the lipoic acid post-translational modification impacts proliferation of colorectal and PIK3CA-mutant cell lines von Doherty, Laura, Sangpo, Tenzin, Tsvetkov, Peter, Davis, John, Dianati, Navid, Schwede, Wolfgang, Zimmermann, Katja, Evans, Laura, Amatucci, Aldo, Seidel, Henrik, Kamburov, Atanas, Akcay, Gizem, Golub, Todd, Eheim, Ashley, Burkhardt, Nils, Eis, Knut, Christian, Sven, Rees, Matt, Roth, Jennifer

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Inhibition of Proliferation and Fibrosis by Vitamin D Agonists—Impact for Uterine Leiomyoma von Wagenfeld, Andrea, Moeller, Carsten, Sandner, Peter, Schwede, Wolfgang, Steinmeyer, Andreas, Zuegel, Ulrich

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Global gene expression profiling of progesterone receptor modulators in T47D cells provides a new classification system von Afhüppe, Wiebke, Sommer, Anette, Müller, Jörg, Schwede, Wolfgang, Fuhrmann, Ulrike, Möller, Carsten

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7α,15α-Ethano bridged steroids. Synthesis and progesterone receptor interaction von Egner, Ursula, Fritzemeier, Karl-Heinrich, Halfbrodt, Wolfgang, Heinrich, Nikolaus, Kuhnke, Joachim, Müller-Fahrnow, Anke, Neef, Günter, Schöllkopf, Klaus, Schwede, Wolfgang

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Investigational developments for the treatment of progesterone-dependent diseases von Möller, Carsten, Hoffmann, Jens, Kirkland, Thomas A, Schwede, Wolfgang

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Beneficial effects of fluorine in the anti-progestin ZK 230211 von Cleve, Arwed, Klar, Ulrich, Schwede, Wolfgang

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Efficient Chiral Pool Synthesis of the C1-C6 Fragment of Epothilones von Klar, Ulrich, Röhr, Bodo, Kuczynski, Frank, Schwede, Wolfgang, Berger, Markus, Skuballa, Werner, Buchmann, Bernd

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