Metabolomic and transcriptomic analysis reveals endogenous substrates and metabolic adaptation in rats lacking Abcg2 and Abcb1a transporters von Ganguly, Samit, Finkelstein, David, Shaw, Timothy I, Michalek, Ryan D, Zorn, Kimberly M, Ekins, Sean, Yasuda, Kazuto, Fukuda, Yu, Schuetz, John D, Mukherjee, Kamalika, Schuetz, Erin G

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Beyond Competitive Inhibition: Regulation of ABC Transporters by Kinases and Protein-Protein Interactions as Potential Mechanisms of Drug-Drug Interactions von Crawford, Rebecca R., Potukuchi, Praveen K., Schuetz, Erin G., Schuetz, John D.

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Zebrafish abcb11b mutant reveals strategies to restore bile excretion impaired by bile salt export pump deficiency von Ellis, Jillian L., Bove, Kevin E., Schuetz, Erin G., Leino, Daniel, Valencia, C. Alexander, Schuetz, John D., Miethke, Alexander, Yin, Chunyue

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Vitamin D levels do not cause vitamin-drug interactions with dexamethasone or dasatinib in mice von Annu, Kavya, Yasuda, Kazuto, Caufield, William V, Freeman, 3rd, Burgess B, Schuetz, Erin G

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Interplay between vitamin D and the drug metabolizing enzyme CYP3A4 von Wang, Zhican, Schuetz, Erin G., Xu, Yang, Thummel, Kenneth E.

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Pheophorbide A: Fluorescent Bcrp Substrate to Measure Oral Drug-Drug Interactions in Real-Time In Vivo von Yasuda, Kazuto, Ganguly, Samit, Schuetz, Erin G.

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Interindividual Variability in Cytochrome P450–Mediated Drug Metabolism von Tracy, Timothy S, Chaudhry, Amarjit S, Prasad, Bhagwat, Thummel, Kenneth E, Schuetz, Erin G, Zhong, Xiao-bo, Tien, Yun-Chen, Jeong, Hyunyoung, Pan, Xian, Shireman, Laura M, Tay-Sontheimer, Jessica, Lin, Yvonne S

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PharmGKB summary: very important pharmacogene information for CYP3A5 von Lamba, Jatinder, Hebert, Joan M, Schuetz, Erin G, Klein, Teri E, Altman, Russ B

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Ketamine Pharmacokinetics and Pharmacodynamics Are Altered by P-Glycoprotein and Breast Cancer Resistance Protein Efflux Transporters in Mice von Ganguly, Samit, Panetta, John C., Roberts, Jessica K., Schuetz, Erin G.

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Genetic Predictors of Interindividual Variability in Hepatic CYP3A4 Expression von Lamba, Vishal, Panetta, John C., Strom, Stephen, Schuetz, Erin G.

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Drug transporters on arachnoid barrier cells contribute to the blood-cerebrospinal fluid barrier von Yasuda, Kazuto, Cline, Cynthia, Vogel, Peter, Onciu, Mihaela, Fatima, Soghra, Sorrentino, Brian P, Thirumaran, Ranjit K, Ekins, Sean, Urade, Yoshihiro, Fujimori, Ko, Schuetz, Erin G

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Polymorphic Human Sulfotransferase 2A1 Mediates the Formation of 25-Hydroxyvitamin D3-3-O-Sulfate, a Major Circulating Vitamin D Metabolite in Humans von Wong, Timothy, Wang, Zhican, Chapron, Brian D., Suzuki, Mizuki, Claw, Katrina G., Gao, Chunying, Foti, Robert S., Prasad, Bhagwat, Chapron, Alenka, Calamia, Justina, Chaudhry, Amarjit, Schuetz, Erin G., Horst, Ronald L., Mao, Qingcheng, de Boer, Ian H., Thornton, Timothy A., Thummel, Kenneth E.

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Genetic contribution to variable human CYP3A-mediated metabolism von Lamba, Jatinder K, Lin, Yvonne S, Schuetz, Erin G, Thummel, Kenneth E

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Human UGT1A4 and UGT1A3 Conjugate 25-Hydroxyvitamin D3: Metabolite Structure, Kinetics, Inducibility, and Interindividual Variability von Wang, Zhican, Wong, Timothy, Hashizume, Takanori, Dickmann, Leslie Z, Scian, Michele, Koszewski, Nicholas J, Goff, Jesse P, Horst, Ronald L, Chaudhry, Amarjit S, Schuetz, Erin G, Thummel, Kenneth E

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ABCC4 impacts megakaryopoiesis and protects megakaryocytes against 6-mercaptopurine induced cytotoxicity von Ranjit, Sabina, Wang, Yao, Zhu, Jingwen, Cheepala, Satish B, Schuetz, Erin G, Cho, Woo Jung, Xu, Beisi, Robinson, Camenzind G, Wu, Gang, Naren, Anjaparavanda P, Schuetz, John D

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Predictors of Variation in CYP2A6 mRNA, Protein, and Enzyme Activity in a Human Liver Bank: Influence of Genetic and Nongenetic Factors von Tanner, Julie-Anne, Prasad, Bhagwat, Claw, Katrina G., Stapleton, Patricia, Chaudhry, Amarjit, Schuetz, Erin G., Thummel, Kenneth E., Tyndale, Rachel F.

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Piperine activates human pregnane X receptor to induce the expression of cytochrome P450 3A4 and multidrug resistance protein 1 von Wang, Yue-Ming, Lin, Wenwei, Chai, Sergio C., Wu, Jing, Ong, Su Sien, Schuetz, Erin G., Chen, Taosheng

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Interactions between Hepatic Mrp4 and Sult2a as Revealed by the Constitutive Androstane Receptor and Mrp4 Knockout Mice von Assem, Mahfoud, Schuetz, Erin G, Leggas, Markos, Sun, Daxi, Yasuda, Kazuto, Reid, Glen, Zelcer, Noam, Adachi, Masashi, Strom, Stephen, Evans, Ronald M, Moore, David D, Borst, Piet, Schuetz, John D

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Systematic genetic and genomic analysis of cytochrome P450 enzyme activities in human liver von Yang, Xia, Zhang, Bin, Molony, Cliona, Chudin, Eugene, Hao, Ke, Zhu, Jun, Gaedigk, Andrea, Suver, Christine, Zhong, Hua, Leeder, J Steven, Guengerich, F Peter, Strom, Stephen C, Schuetz, Erin, Rushmore, Thomas H, Ulrich, Roger G, Slatter, J Greg, Schadt, Eric E, Kasarskis, Andrew, Lum, Pek Yee

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Comprehensive Pharmacogenetic Analysis of Irinotecan Neutropenia and Pharmacokinetics von INNOCENTI, Federico, KROETZ, Deanna L, SCHUETZ, Erin, DOLAN, M. Eileen, RAMIREZ, Jacqueline, RELLING, Mary, PEIXIAN CHEN, DAS, Soma, ROSNER, Gary L, RATAIN, Mark J

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