Concomitant epigenetic targeting of LSD1 and HDAC synergistically induces mitochondrial apoptosis in rhabdomyosarcoma cells von Haydn, Tinka, Metzger, Eric, Schuele, Roland, Fulda, Simone

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LSD1 inhibition circumvents glucocorticoid-induced muscle wasting of male mice von Cai, Qingshuang, Sahu, Rajesh, Ueberschlag-Pitiot, Vanessa, Souali-Crespo, Sirine, Charvet, Céline, Silem, Ilyes, Cottard, Félicie, Ye, Tao, Taleb, Fatima, Metzger, Eric, Schuele, Roland, Billas, Isabelle M. L., Laverny, Gilles, Metzger, Daniel, Duteil, Delphine

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Transcriptional repressor NIR functions in the ribosome RNA processing of both 40S and 60S subunits von Wu, Jianguo, Zhang, Ying, Wang, Yingshuang, Kong, Ruirui, Hu, Lelin, Schuele, Roland, Du, Xiaojuan, Ke, Yang

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Lysine-specific demethylase 1 (LSD1) is highly expressed in ER-negative breast cancers and a biomarker predicting aggressive biology von Lim, Soyoung, Janzer, Andreas, Becker, Astrid, Zimmer, Andreas, Schüle, Roland, Buettner, Reinhard, Kirfel, Jutta

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RORβ Spinal Interneurons Gate Sensory Transmission during Locomotion to Secure a Fluid Walking Gait von Koch, Stephanie C., Del Barrio, Marta Garcia, Dalet, Antoine, Gatto, Graziana, Günther, Thomas, Zhang, Jingming, Seidler, Barbara, Saur, Dieter, Schüle, Roland, Goulding, Martyn

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Next‐generation sequencing reveals a novel role of lysine‐specific demethylase 1 in adhesion of rhabdomyosarcoma cells von Haydn, Tinka, Kehr, Sarah, Willmann, Dominica, Metzger, Eric, Schüle, Roland, Fulda, Simone

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Lsd1 prevents age-programed loss of beige adipocytes von Duteil, Delphine, Tosic, Milica, Willmann, Dominica, Georgiadi, Anastasia, Kanouni, Toufike, Schüle, Roland

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Lsd1 regulates skeletal muscle regeneration and directs the fate of satellite cells von Tosic, Milica, Allen, Anita, Willmann, Dominica, Lepper, Christoph, Kim, Johnny, Duteil, Delphine, Schüle, Roland

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Epigenetics meets GPCR: inhibition of histone H3 methyltransferase (G9a) and histamine H3 receptor for Prader–Willi Syndrome von Reiner, David, Seifert, Ludwig, Deck, Caroline, Schüle, Roland, Jung, Manfred, Stark, Holger

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KDM4 Inhibition Targets Breast Cancer Stem-like Cells von Metzger, Eric, Stepputtis, Stella S, Strietz, Juliane, Preca, Bogdan-Tiberius, Urban, Sylvia, Willmann, Dominica, Allen, Anita, Zenk, Fides, Iovino, Nicola, Bronsert, Peter, Proske, Amelie, Follo, Marie, Boerries, Melanie, Stickeler, Elmar, Xu, Jiangchun, Wallace, Michael B, Stafford, Jeffrey A, Kanouni, Toufike, Maurer, Jochen, Schüle, Roland

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4-Acyl Pyrroles: Mimicking Acetylated Lysines in Histone Code Reading von Lucas, Xavier, Wohlwend, Daniel, Hügle, Martin, Schmidtkunz, Karin, Gerhardt, Stefan, Schüle, Roland, Jung, Manfred, Einsle, Oliver, Günther, Stefan

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Androgen receptor coactivators lysine-specific histone demethylase 1 and four and a half LIM domain protein 2 predict risk of prostate cancer recurrence von KAHL, Philip, GULLOTTI, Lucia, SCHÜLE, Roland, BUETTNER, Reinhard, HEUKAMP, Lukas Carl, WOLF, Susanne, FRIEDRICHS, Nicolaus, VORREUTHER, Roland, SOLLEDER, Gerold, BASTIAN, Patrick J, ELLINGER, Jörg, METZGER, Eric

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KMT9 monomethylates histone H4 lysine 12 and controls proliferation of prostate cancer cells von Metzger, Eric, Wang, Sheng, Urban, Sylvia, Willmann, Dominica, Schmidt, Andreas, Offermann, Anne, Allen, Anita, Sum, Manuela, Obier, Nadine, Cottard, Félicie, Ulferts, Svenja, Preca, Bogdan-Tiberius, Hermann, Bianca, Maurer, Jochen, Greschik, Holger, Hornung, Veit, Einsle, Oliver, Perner, Sven, Imhof, Axel, Jung, Manfred, Schüle, Roland

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Structure–Activity Studies of 1,2,4-Oxadiazoles for the Inhibition of the NAD+‑Dependent Lysine Deacylase Sirtuin 2 von Colcerasa, Arianna, Friedrich, Florian, Melesina, Jelena, Moser, Patrick, Vogelmann, Anja, Tzortzoglou, Pavlos, Neuwirt, Emilia, Sum, Manuela, Robaa, Dina, Zhang, Lin, Ramos-Morales, Elizabeth, Romier, Christophe, Einsle, Oliver, Metzger, Eric, Schüle, Roland, Groß, Olaf, Sippl, Wolfgang, Jung, Manfred

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Identification of a small-molecule ligand of the epigenetic reader protein Spindlin1 via a versatile screening platform von Wagner, Tobias, Greschik, Holger, Burgahn, Teresa, Schmidtkunz, Karin, Schott, Anne-Kathrin, McMillan, Joel, Baranauskienė, Lina, Xiong, Yan, Fedorov, Oleg, Jin, Jian, Oppermann, Udo, Matulis, Daumantas, Schüle, Roland, Jung, Manfred

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Discovery of a Potent, Selective, and Cell-Active SPIN1 Inhibitor von Xiong, Yan, Greschik, Holger, Johansson, Catrine, Seifert, Ludwig, Gamble, Vicki, Park, Kwang-su, Fagan, Vincent, Li, Fengling, Chau, Irene, Vedadi, Masoud, Arrowsmith, Cheryl H., Brennan, Paul, Fedorov, Oleg, Jung, Manfred, Farnie, Gillian, Liu, Jing, Oppermann, Udo, Schüle, Roland, Jin, Jian

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Experimental in vitro, ex vivo and in vivo models in prostate cancer research von Sailer, Verena, von Amsberg, Gunhild, Duensing, Stefan, Kirfel, Jutta, Lieb, Verena, Metzger, Eric, Offermann, Anne, Pantel, Klaus, Schuele, Roland, Taubert, Helge, Wach, Sven, Perner, Sven, Werner, Stefan, Aigner, Achim

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Cooperative demethylation by JMJD2C and LSD1 promotes androgen receptor-dependent gene expression von Vogler, Christine, Metzger, Eric, Schneider, Robert, Schüle, Roland, Wissmann, Melanie, Yin, Na, Müller, Judith M, Fodor, Barna D, Jenuwein, Thomas, Buettner, Reinhard, Greschik, Holger, Günther, Thomas

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