Acid sphingomyelinase, cell membranes and human disease: Lessons from Niemann–Pick disease von Schuchman, Edward H.

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Deregulation of sphingolipid metabolism in Alzheimer's disease von He, Xingxuan, Huang, Yu, Li, Bin, Gong, Cheng-Xin, Schuchman, Edward H

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unexpected role of acid sphingomyelinase in cell death and the pathophysiology of common diseases von Smith, Eric L, Schuchman, Edward H

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Acid sphingomyelinase modulates the autophagic process by controlling lysosomal biogenesis in Alzheimer's disease von Lee, Jong Kil, Jin, Hee Kyung, Park, Min Hee, Kim, Bo-ra, Lee, Phil Hyu, Nakauchi, Hiromitsu, Carter, Janet E, He, Xingxuan, Schuchman, Edward H, Bae, Jae-sung

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Control of Endothelial Targeting and Intracellular Delivery of Therapeutic Enzymes by Modulating the Size and Shape of ICAM-1-targeted Carriers von Muro, Silvia, Garnacho, Carmen, Champion, Julie A, Leferovich, John, Gajewski, Christine, Schuchman, Edward H, Mitragotri, Samir, Muzykantov, Vladimir R

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Types A and B Niemann-Pick disease von Schuchman, Edward H., PhD, Wasserstein, Melissa P., MD

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Identification of a Novel Acid Sphingomyelinase Activity Associated with Recombinant Human Acid Ceramidase von He, Xingxuan, Schuchman, Edward H

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Immunotherapy targeting plasma ASM is protective in a mouse model of Alzheimer’s disease von Choi, Byung Jo, Park, Min Hee, Park, Kang Ho, Han, Wan Hui, Yoon, Hee Ji, Jung, Hye Yoon, Hong, Ju Yeon, Chowdhury, Md Riad, Kim, Kyung Yeol, Lee, Jihoon, Song, Im-Sook, Pang, Minyeong, Choi, Min-Koo, Gulbins, Erich, Reichel, Martin, Kornhuber, Johannes, Hong, Chang-Won, Kim, Changho, Kim, Seung Hyun, Schuchman, Edward H., Jin, Hee Kyung, Bae, Jae-sung

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Intracerebral Transplantation of Bone Marrow‐Derived Mesenchymal Stem Cells Reduces Amyloid‐Beta Deposition and Rescues Memory Deficits in Alzheimer's Disease Mice by Modulation of... von Lee, Jong Kil, Jin, Hee Kyung, Endo, Shogo, Schuchman, Edward H., Carter, Janet E., Bae, Jae‐sung

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Neuronal SphK1 acetylates COX2 and contributes to pathogenesis in a model of Alzheimer’s Disease von Lee, Ju Youn, Han, Seung Hoon, Park, Min Hee, Baek, Bosung, Song, Im-Sook, Choi, Min-Koo, Takuwa, Yoh, Ryu, Hoon, Kim, Seung Hyun, He, Xingxuan, Schuchman, Edward H., Bae, Jae-Sung, Jin, Hee Kyung

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N-AS-triggered SPMs are direct regulators of microglia in a model of Alzheimer’s disease von Lee, Ju Youn, Han, Seung Hoon, Park, Min Hee, Song, Im-Sook, Choi, Min-Koo, Yu, Eunsoo, Park, Cheol-Min, Kim, Hee-Jin, Kim, Seung Hyun, Schuchman, Edward H., Jin, Hee Kyung, Bae, Jae-sung

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The cholesterol transporter NPC1 is essential for epigenetic regulation and maturation of oligodendrocyte lineage cells von Kunkel, Thaddeus J., Townsend, Alice, Sullivan, Kyle A., Merlet, Jean, Schuchman, Edward H., Jacobson, Daniel A., Lieberman, Andrew P.

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Recombinant human acid sphingomyelinase as an adjuvant to sorafenib treatment of experimental liver cancer von Savić, Radoslav, He, Xingxuan, Fiel, Isabel, Schuchman, Edward H

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Pentosan Polysulfate: Oral Versus Subcutaneous Injection in Mucopolysaccharidosis Type I Dogs von Simonaro, Calogera M, Tomatsu, Shunji, Sikora, Tracy, Kubaski, Francyne, Frohbergh, Michael, Guevara, Johana M, Wang, Raymond Y, Vera, Moin, Kang, Jennifer L, Smith, Lachlan J, Schuchman, Edward H, Haskins, Mark E

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New paradigms for the treatment of lysosomal storage diseases: targeting the endocannabinoid system as a therapeutic strategy von Schuchman, Edward H, Ledesma, Maria D, Simonaro, Calogera M

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Modulation of Dietary Choline Uptake in a Mouse Model of Acid Sphingomyelinase Deficiency von Gaudioso, Ángel, Moreno-Huguet, Pilar, Casas, Josefina, Schuchman, Edward H, Ledesma, María Dolores

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Pentosan polysulfate: a novel therapy for the mucopolysaccharidoses von Schuchman, Edward H, Ge, Yi, Lai, Alon, Borisov, Yury, Faillace, Meghan, Eliyahu, Efrat, He, Xingxuan, Iatridis, James, Vlassara, Helen, Striker, Gary, Simonaro, Calogera M

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Sphingomyelin 16:0 is a therapeutic target for neuronal death in acid sphingomyelinase deficiency von Gaudioso, Ángel, Jiang, Xuntian, Casas, Josefina, Schuchman, Edward H., Ledesma, María Dolores

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Involvement of the Toll-like receptor 4 pathway and use of TNF-α antagonists for treatment of the mucopolysaccharidoses von Simonaro, Calogera M, Ge, Yi, Eliyahu, Efrat, He, Xingxuan, Jepsen, Karl J, Schuchman, Edward H

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Apolipoprotein D-mediated preservation of lysosomal function promotes cell survival and delays motor impairment in Niemann-Pick type A disease von Pascua-Maestro, Raquel, Corraliza-Gomez, Miriam, Fadrique-Rojo, Cristian, Ledesma, Maria D., Schuchman, Edward H., Sanchez, Diego, Ganfornina, Maria D.

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