Palladium-Catalyzed Asymmetric Allylic Alkylation of Ketone Enolates von Trost, Barry M., Schroeder, Gretchen M.

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Antibody–drug conjugates: current status and future directions von Perez, Heidi L., Cardarelli, Pina M., Deshpande, Shrikant, Gangwar, Sanjeev, Schroeder, Gretchen M., Vite, Gregory D., Borzilleri, Robert M.

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Exploiting the Pd- and Ru-Catalyzed Cycloisomerizations:  Enantioselective Total Synthesis of (+)-Allocyathin B2 von Trost, Barry M, Dong, Li, Schroeder, Gretchen M

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An Asymmetric Synthesis of Hamigeran B via a Pd Asymmetric Allylic Alkylation for Enantiodiscrimination von Trost, Barry M, Pissot-Soldermann, Carole, Chen, Irwin, Schroeder, Gretchen M

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Discovery of orally active pyrrolopyridine- and aminopyridine-based Met kinase inhibitors von Cai, Zhen-Wei, Wei, Donna, Schroeder, Gretchen M., Cornelius, Lyndon A.M., Kim, Kyoung, Chen, Xiao-Tao, Schmidt, Robert J., Williams, David K., Tokarski, John S., An, Yongmi, Sack, John S., Manne, Veeraswamy, Kamath, Amrita, Zhang, Yueping, Marathe, Punit, Hunt, John T., Lombardo, Louis J., Fargnoli, Joseph, Borzilleri, Robert M.

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Discovery of Non-Nucleotide Small-Molecule STING Agonists via Chemotype Hybridization von Cherney, Emily C, Zhang, Liping, Lo, Julian, Huynh, Tram, Wei, Donna, Ahuja, Vijay, Quesnelle, Claude, Schieven, Gary L, Futran, Alan, Locke, Gregory A, Lin, Zeyu, Monereau, Laura, Chaudhry, Charu, Blum, Jordan, Li, Sha, Fereshteh, Mark, Li-Wang, Bifang, Gangwar, Sanjeev, Pan, Chin, Chong, Colin, Zhu, Xiao, Posy, Shana L, Sack, John S, Zhang, Ping, Ruzanov, Max, Harner, Mary, Akhtar, Fahad, Schroeder, Gretchen M, Vite, Gregory, Fink, Brian

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Design, Synthesis, and Pharmacological Evaluation of Second-Generation Tetrahydroisoquinoline-Based CXCR4 Antagonists with Favorable ADME Properties von Nguyen, Huy H., Kim, Michelle B., Wilson, Robert J., Butch, Christopher J., Kuo, Katie M., Miller, Eric J., Tahirovic, Yesim A., Jecs, Edgars, Truax, Valarie M., Wang, Tao, Sum, Chi S., Cvijic, Mary E., Schroeder, Gretchen M., Wilson, Lawrence J., Liotta, Dennis C.

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Cyclic 1,2-Diketones as Building Blocks for Asymmetric Synthesis of Cycloalkenones von Trost, Barry M, Schroeder, Gretchen M

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Discovery of N-(4-(2-Amino-3-chloropyridin-4-yloxy)-3-fluorophenyl)-4-ethoxy-1-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide (BMS-777607), a Selective and Orally Efficac... von Schroeder, Gretchen M, An, Yongmi, Cai, Zhen-Wei, Chen, Xiao-Tao, Clark, Cheryl, Cornelius, Lyndon A. M, Dai, Jun, Gullo-Brown, Johnni, Gupta, Ashok, Henley, Benjamin, Hunt, John T, Jeyaseelan, Robert, Kamath, Amrita, Kim, Kyoung, Lippy, Jonathan, Lombardo, Louis J, Manne, Veeraswamy, Oppenheimer, Simone, Sack, John S, Schmidt, Robert J, Shen, Guoxiang, Stefanski, Kevin, Tokarski, John S, Trainor, George L, Wautlet, Barri S, Wei, Donna, Williams, David K, Zhang, Yingru, Zhang, Yueping, Fargnoli, Joseph, Borzilleri, Robert M

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Synthesis and Evaluation of Novel Tetrahydronaphthyridine CXCR4 Antagonists with Improved Drug-like Profiles von Jecs, Edgars, Tahirovic, Yesim A, Wilson, Robert J, Miller, Eric J, Kim, Michelle, Truax, Valarie, Nguyen, Huy H, Akins, Nicholas S, Saindane, Manohar, Wang, Tao, Sum, Chi S, Cvijic, Mary E, Schroeder, Gretchen M, Burton, Samantha L, Derdeyn, Cynthia A, Xu, Lingjie, Jiang, Yi, Wilson, Lawrence J, Liotta, Dennis C

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Discovery of Tetrahydroisoquinoline-Containing CXCR4 Antagonists with Improved in Vitro ADMET Properties von Miller, Eric J, Jecs, Edgars, Truax, Valarie M, Katzman, Brooke M, Tahirovic, Yesim A, Wilson, Robert J, Kuo, Katie M, Kim, Michelle B, Nguyen, Huy H, Saindane, Manohar T, Zhao, Huanyu, Wang, Tao, Sum, Chi S, Cvijic, Mary E, Schroeder, Gretchen M, Wilson, Lawrence J, Liotta, Dennis C

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Synthesis and SAR of pyrrolotriazine-4-one based Eg5 inhibitors von Kim, Kyoung Soon, Lu, Songfeng, Cornelius, Lyndon A., Lombardo, Louis J., Borzilleri, Robert M., Schroeder, Gretchen M., Sheng, Christopher, Rovnyak, George, Crews, Donald, Schmidt, Robert J., Williams, David K., Bhide, Rajeev S., Traeger, Sarah C., McDonnell, Patricia A., Mueller, Luciano, Sheriff, Steven, Newitt, John A., Pudzianowski, Andrew T., Yang, Zheng, Wild, Robert, Lee, Frances Y., Batorsky, Roberta, Ryder, James S., Ortega-Nanos, Marie, Shen, Henry, Gottardis, Marco, Roussell, Deborah L.

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Amino-Heterocycle Tetrahydroisoquinoline CXCR4 Antagonists with Improved ADME Profiles via Late-Stage Buchwald Couplings von Nguyen, Huy H, Tahirovic, Yesim A, Truax, Valarie M, Wilson, Robert J, Jecs, Edgars, Miller, Eric J, Kim, Michelle B, Akins, Nicholas S, Xu, Lingjie, Jiang, Yi, Wang, Tao, Sum, Chi S, Cvijic, Mary E, Schroeder, Gretchen M, Wilson, Lawrence J, Liotta, Dennis C

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Macrocyclic pyrrolobenzodiazepine dimers as antibody-drug conjugate payloads von Donnell, Andrew F., Zhang, Yong, Stang, Erik M., Wei, Donna D., Tebben, Andrew J., Perez, Heidi L., Schroeder, Gretchen M., Pan, Chin, Rao, Chetana, Borzilleri, Robert M., Vite, Gregory D., Gangwar, Sanjeev

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Palladium-Catalyzed Asymmetric Alkylation of Ketone Enolates von Trost, Barry M, Schroeder, Gretchen M

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Intramolecular Palladium-Catalyzed Allylic Alkylation:  Enantio- and Diastereoselective Synthesis of [2.2.2] Bicycles von Trost, Barry M, Sacchi, Karna L, Schroeder, Gretchen M, Asakawa, Naoyuki

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Tetrahydroisoquinoline CXCR4 Antagonists Adopt a Hybrid Binding Mode within the Peptide Subpocket of the CXCR4 Receptor von Katzman, Brooke M, Cox, Bryan D, Prosser, Anthony R, Alcaraz, Ana A, Murat, Brigitte, Héroux, Madeleine, Tebben, Andrew, Zhang, Yong, Schroeder, Gretchen M, Snyder, James P, Wilson, Lawrence J, Liotta, Dennis C

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Palladium-Catalyzed Asymmetric Allylic Alkylation of Barbituric Acid Derivatives:  Enantioselective Syntheses of Cyclopentobarbital and Pentobarbital von Trost, Barry M, Schroeder, Gretchen M

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Synthesis of Novel Tetrahydroisoquinoline CXCR4 Antagonists with Rigidified Side-Chains von Jecs, Edgars, Miller, Eric J, Wilson, Robert J, Nguyen, Huy H, Tahirovic, Yesim A, Katzman, Brook M, Truax, Valarie M, Kim, Michelle B, Kuo, Katie M, Wang, Tao, Sum, Chi S, Cvijic, Mary E, Schroeder, Gretchen M, Wilson, Lawrence J, Liotta, Dennis C

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Synthesis and SAR of 1,2,3,4-Tetrahydroisoquinoline-Based CXCR4 Antagonists von Wilson, Robert J, Jecs, Edgars, Miller, Eric J, Nguyen, Huy H, Tahirovic, Yesim A, Truax, Valarie M, Kim, Michelle B, Kuo, Katie M, Wang, Tao, Sum, Chi Shing, Cvijic, Mary E, Paiva, Anthony A, Schroeder, Gretchen M, Wilson, Lawrence J, Liotta, Dennis C

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