Structure-guided engineering of the affinity and specificity of CARs against Tn-glycopeptides von Sharma, Preeti, Marada, Venkata V. V. R., Cai, Qi, Kizerwetter, Monika, He, Yanran, Wolf, Steven P., Schreiber, Karin, Clausen, Henrik, Schreiber, Hans, Kranz, David M.

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IL-15 in tumor microenvironment causes rejection of large established tumors by T cells in a noncognate T cell receptor-dependent manner von Liu, Rebecca Berlant, Engels, Boris, Schreiber, Karin, Ciszewski, Cezary, Schietinger, Andrea, Schreiber, Hans, Jabri, Bana

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Cooperation of genes in HPV16 E6/E7-dependent cervicovaginal carcinogenesis trackable by endoscopy and independent of exogenous estrogens or carcinogens von Böttinger, Paula, Schreiber, Karin, Hyjek, Elizabeth, Krausz, Thomas, Spiotto, Michael T, Steiner, Madeline, Idel, Christian, Booras, Heather, Beck-Engeser, Gabriele, Riederer, Jessie, Willimsky, Gerald, Wolf, Steven P, Karrison, Theodore, Jensen, Elizabeth, Weichselbaum, Ralph R, Nakamura, Yusuke, Yew, Poh Yin, Lambert, Paul F, Kurita, Takeshi, Kiyotani, Kazuma, Leisegang, Matthias, Schreiber, Hans

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Impact of TCR Diversity on the Development of Transplanted or Chemically Induced Tumors von Schreiber, Karin, Karrison, Theodore G, Wolf, Steven P, Kiyotani, Kazuma, Steiner, Madeline, Littmann, Eric R, Pamer, Eric G, Kammertoens, Thomas, Schreiber, Hans, Leisegang, Matthias

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Densely Granulated Murine NK Cells Eradicate Large Solid Tumors von LIU, Rebecca B, ENGELS, Boris, JABRI, Bana, SCHREIBER, Hans, ARINA, Ainhoa, SCHREIBER, Karin, HYJEK, Elizabeth, SCHIETINGER, Andrea, BINDER, David C, BUTZ, Eric, KRAUSZ, Thomas, ROWLEY, Donald A

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Single CAR-T cell treatment controls disseminated ovarian cancer in a syngeneic mouse model von Ranoa, Diana Rose E, Sharma, Preeti, Schane, Claire P, Lewis, Amber N, Valdez, Edward, Marada, Venkata V V R, Hager, Marlies V, Montgomery, Will, Wolf, Steven P, Schreiber, Karin, Schreiber, Hans, Bailey, Keith, Fan, Timothy M, Hergenrother, Paul J, Roy, Edward J, Kranz, David M

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Multiple cancer-specific antigens are targeted by a chimeric antibody receptor on a single cancer cell von He, Yanran, Schreiber, Karin, Wolf, Steven P., Wen, Frank, Steentoft, Catharina, Zerweck, Jonathan, Steiner, Madeline, Sharma, Preeti, Shepard, H. Michael, Posey, Avery, June, Carl H., Mandel, Ulla, Clausen, Henrik, Leisegang, Matthias, Meredith, Stephen C., Kranz, David M., Schreiber, Hans

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Assessment of coronary flow reserve: comparison between contrast-enhanced magnetic resonance imaging and positron emission tomography von Ibrahim, Tareq, Nekolla, Stephan G., Schreiber, Karin, Odaka, Kenichi, Volz, Stefan, Mehilli, Julinda, Güthlin, Martin, Delius, Wolfram, Schwaiger, Markus

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Engineered CAR T Cells Targeting the Cancer-Associated Tn-Glycoform of the Membrane Mucin MUC1 Control Adenocarcinoma von Posey, Avery D., Schwab, Robert D., Boesteanu, Alina C., Steentoft, Catharina, Mandel, Ulla, Engels, Boris, Stone, Jennifer D., Madsen, Thomas D., Schreiber, Karin, Haines, Kathleen M., Cogdill, Alexandria P., Chen, Taylor J., Song, Decheng, Scholler, John, Kranz, David M., Feldman, Michael D., Young, Regina, Keith, Brian, Schreiber, Hans, Clausen, Henrik, Johnson, Laura A., June, Carl H.

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Bystander killing of cancer requires the cooperation of CD4(+) and CD8(+) T cells during the effector phase von Schietinger, Andrea, Philip, Mary, Liu, Rebecca B, Schreiber, Karin, Schreiber, Hans

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Eradication of Large Solid Tumors by Gene Therapy with a T-Cell Receptor Targeting a Single Cancer-Specific Point Mutation von Leisegang, Matthias, Engels, Boris, Schreiber, Karin, Yew, Poh Yin, Kiyotani, Kazuma, Idel, Christian, Arina, Ainhoa, Duraiswamy, Jaikumar, Weichselbaum, Ralph R, Uckert, Wolfgang, Nakamura, Yusuke, Schreiber, Hans

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E-102 Destruction of the tumor microenvironment by neoantigen-specific T cells prevents relapse of therapy-resistant cancer variants von Wolf, Steven, Schreiber, Karin, Steiner, Madeline, Weichselbaum, Ralph, Leisegang, Matthias, Schreiber, Hans

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Abstract 3238: Engineering chimeric antigen receptors for adoptive T cell therapy of cancers that express the Tn antigen von Sharma, Preeti, Marada, Venkata VVR, Kizerwetter, Monika, Schane, Claire P., He, Yanran, Wolf, Steven P., Schreiber, Karin, Roy, Edward J., Clausen, Henrik, Schreiber, Hans, Kranz, David M.

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Abstract 3587: TCR-transduced T cells targeting a truncal mutation caused by a nsSNV destroy large solid tumors despite intratumoral genetic heterogeneity von Leisegang, Matthias, Schreiber, Karin, Wolf, Steven P., Anastosopolou, Vasiliki, Borutta, Kimberley, Yew, PohYin, Kiyotani, Kazuma, Nakamura, Yusuke, Schreiber, Hans

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Spleen Cells from Young Donors Eradicate Large Tumors–Response von Rowley, Donald A., Schreiber, Karin, Schreiber, Hans

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Transfer of Allogeneic CD4+ T Cells Rescues CD8+ T Cells in Anti-PD-L1-Resistant Tumors Leading to Tumor Eradication von Arina, Ainhoa, Karrison, Theodore, Galka, Eva, Schreiber, Karin, Weichselbaum, Ralph R, Schreiber, Hans

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Adoptively transferred immune T cells eradicate established tumors despite cancer-induced immune suppression von Arina, Ainhoa, Schreiber, Karin, Binder, David C, Karrison, Theodore G, Liu, Rebecca B, Schreiber, Hans

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Adoptively transferred immune T cells eradicate established tumors in spite of cancer-induced immune suppression von Arina, Ainhoa, Schreiber, Karin, Binder, David C., Karrison, Theodore, Liu, Rebecca B., Schreiber, Hans

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Tracking the Common Ancestry of Antigenically Distinct Cancer Variants von SCHREIBER, Karin, WU, Terry H, KAST, W. Martin, SCHREIBER, Hans

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Multiple cancer-specific antigens are targeted by a chimeric antigen receptor on a single cancer cell von He, Yanran, Schreiber, Karin, Wolf, Steven P, Wen, Frank, Steentoft, Catharina, Zerweck, Jonathan, Steiner, Madeline, Sharma, Preeti, Shepard, H Michael, Posey, Avery, June, Carl H, Mandel, Ulla, Clausen, Henrik, Leisegang, Matthias, Meredith, Stephen C, Kranz, David M, Schreiber, Hans

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