Autophagy Promotes MHC Class II Presentation of Peptides from Intracellular Source Proteins von Dengjel, Jörn, Schoor, Oliver, Fischer, Rainer, Reich, Michael, Kraus, Marianne, Müller, Margret, Kreymborg, Katharina, Altenberend, Florian, Brandenburg, Jens, Kalbacher, Hubert, Brock, Roland, Driessen, Christoph, Rammensee, Hans-Georg, Stevanovic, Stefan, Cresswell, Peter

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First-in-human dose escalation trial to evaluate the clinical safety and efficacy of an anti-MAGEA1 autologous TCR-transgenic T cell therapy in relapsed and refractory solid tumors von Wermke, Martin, Holderried, Tobias A W, Luke, Jason John, Morris, Van K, Alsdorf, Winfried H, Wetzko, Katrin, Andersson, Borje S, Wistuba, Ignacio I, Parra, Edwin R, Hossain, Mohammad B, Grund-Gröschke, Sandra, Aslan, Katrin, Satelli, Arun, Marisetty, Anantha, Satam, Swapna, Kalra, Mamta, Hukelmann, Jens, Kursunel, M Alper, Pozo, Karine, Acs, Andreas, Backert, Linus, Baumeister, Melissa, Bunk, Sebastian, Wagner, Claudia, Schoor, Oliver, Mohamed, Ali S, Mayer-Mokler, Andrea, Hilf, Norbert, Krishna, Delfi, Walter, Steffen, Tsimberidou, Apostolia M, Britten, Cedrik M

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Distorted Relation between mRNA Copy Number and Corresponding Major Histocompatibility Complex Ligand Density on the Cell Surface von Weinzierl, Andreas O, Lemmel, Claudia, Schoor, Oliver, Müller, Margret, Krüger, Tobias, Wernet, Dorothee, Hennenlotter, Jörg, Stenzl, Arnulf, Klingel, Karin, Rammensee, Hans-Georg, Stevanovic, Stefan

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Effects of Imatinib on Monocyte-Derived Dendritic Cells Are Mediated by Inhibition of Nuclear Factor-κB and Akt Signaling Pathways von APPEL, Silke, RUPF, Anette, WECK, Markus M, SCHOOR, Oliver, BRÜMMENDORF, Tim H, WEINSCHENK, Toni, GRÜNEBACH, Frank, BROSSART, Peter

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Moderate degradation does not preclude microarray analysis of small amounts of RNA von Schoor, Oliver, Weinschenk, Toni, Hennenlotter, Jörg, Corvin, Stefan, Stenzl, Arnulf, Rammensee, Hans-Georg, Stevanovi, Stefan

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Unexpected Abundance of HLA Class II Presented Peptides in Primary Renal Cell Carcinomas von DENGJEL, Jörn, NASTKE, Maria-Dorothea, HENNENLOTTER, Jorg, WERNET, Dorothee, STENZL, Arnulf, RAMMENSEE, Hans-Georg, KLINGEL, Karin, STEVANOVIC, Stefan, GOUTTEFANGEAS, Cécile, GITSIOUDIS, Gitsios, SCHOOR, Oliver, ALTENBEREND, Florian, MÜLLER, Margret, KRÄMER, Björn, MISSIOU, Anna, SAUTER, Martina

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Multipeptide immune response to cancer vaccine IMA901 after single-dose cyclophosphamide associates with longer patient survival von Walter, Steffen, Weinschenk, Toni, Stenzl, Arnulf, Zdrojowy, Romuald, Pluzanska, Anna, Szczylik, Cezary, Staehler, Michael, Brugger, Wolfram, Dietrich, Pierre-Yves, Mendrzyk, Regina, Hilf, Norbert, Schoor, Oliver, Fritsche, Jens, Mahr, Andrea, Maurer, Dominik, Vass, Verona, Trautwein, Claudia, Lewandrowski, Peter, Flohr, Christian, Pohla, Heike, Stanczak, Janusz J, Bronte, Vincenzo, Mandruzzato, Susanna, Biedermann, Tilo, Pawelec, Graham, Derhovanessian, Evelyna, Yamagishi, Hisakazu, Miki, Tsuneharu, Hongo, Fumiya, Takaha, Natsuki, Hirakawa, Kosei, Tanaka, Hiroaki, Stevanovic, Stefan, Frisch, Jürgen, Mayer-Mokler, Andrea, Kirner, Alexandra, Rammensee, Hans-Georg, Reinhardt, Carsten, Singh-Jasuja, Harpreet

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Pitfalls in HLA Ligandomics—How to Catch a Li(e)gand von Fritsche, Jens, Kowalewski, Daniel J., Backert, Linus, Gwinner, Frederik, Dorner, Sonja, Priemer, Martin, Tsou, Chih-Chiang, Hoffgaard, Franziska, Römer, Michael, Schuster, Heiko, Schoor, Oliver, Weinschenk, Toni

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Exploiting the glioblastoma peptidome to discover novel tumour-associated antigens for immunotherapy von DUTOIT, Valérie, HEROLD-MENDE, Christel, LOHR, Jennifer, RAMMENSEE, Hans-Georg, STEVANOVIC, Stefan, TRAUTWEIN, Claudia, VASS, Verona, WALTER, Steffen, WALKER, Paul R, WEINSCHENK, Toni, SINGH-JASUJA, Harpreet, DIETRICH, Pierre-Yves, HILF, Norbert, SCHOOR, Oliver, BECKHOVE, Philipp, BUCHER, Judith, DORSCH, Katharina, FLOHR, Sylvia, FRITSCHE, Jens, LEWANDROWSKI, Peter

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IMA402, an Off-the-Shelf, Next-Generation TCR Bispecific (TCER®) for Efficiently Targeting an HLA-Presented Peptide from the Pan-Cancer Antigen PRAME von Bunk, Sebastian, Hofmann, Martin, Pszolla, Gabriele, Hutt, Meike, Schwöbel, Frank, Unverdorben, Felix, Aschmoneit, Nadine, Wagner, Claudia, Jaworski, Maike, Schuster, Heiko, Schwoerer, Florian, Schraeder, Christoph, Schoor, Oliver, Missel, Sarah, Weinschenk, Toni, Maurer, Dominik, Reinhardt, Carsten

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Abstract 662: IMA_Detect: Mass spectrometry guided development and clinical application of a companion diagnostic for adoptive cellular therapy against tumor associated HLA peptide... von Fritsche, Jens, Satelli, Arun, Hörzer, Helen, Rakitsch, Barbara, Hoffgaard, Franziska, Hilf, Norbert, Schoor, Oliver, Singh-Jasuja, Harpreet, Toni, Weinschenk

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Translating Immunopeptidomics to Immunotherapy‐Decision‐Making for Patient and Personalized Target Selection von Fritsche, Jens, Rakitsch, Barbara, Hoffgaard, Franziska, Römer, Michael, Schuster, Heiko, Kowalewski, Daniel J., Priemer, Martin, Stos‐Zweifel, Vlatka, Hörzer, Helen, Satelli, Arun, Sonntag, Annika, Goldfinger, Valentina, Song, Colette, Mahr, Andrea, Ott, Martina, Schoor, Oliver, Weinschenk, Toni

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Effective Targeting of PRAME-Positive Tumors with Bispecific T Cell-Engaging Receptor (TCER®) Molecules von Bunk, Sebastian, Hofmann, Martin, Unverdorben, Felix, Hutt, Meike, Pszolla, Gabriele, Schwöbel, Frank, Wagner, Claudia, Yousef, Sara, Schuster, Heiko, Missel, Sarah, Schoor, Oliver, Weinschenk, Toni, Singh-Jasuja, Harpreet, Maurer, Dominik, Reinhardt, Carsten

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Abstract 2789: Development of highly potent T-cell receptor bispecifics with picomolar activity against tumor-specific HLA ligands von Bunk, Sebastian, Hofmann, Martin, Unverdorben, Felix, Alten, Leonie, Hutt, Meike, Wagner, Claudia, Schoor, Oliver, Ferber, Mathias, Fritsche, Jens, Weinschenk, Toni, Singh-Jasuja, Harpreet, Maurer, Dominik, Reinhardt, Carsten

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Abstract CT127: Phase I adoptive cellular therapy trial with actively personalized, multi-targeted CD8+ T-cells in patients with relapsed and/or refractory solid cancers (ACTologIM... von Ma, Hong, Kuttruff, Sabrina, Stewart, Chad, Bulliard, Yannick, Stephens, Geoffrey, Schoor, Oliver, Satelli, Arun, Hilf, Norbert, Sieger, Kerry, Fritsche, Jens, Maurer, Dominik, Mohamed, Ali, Weinschenk, Toni, Reinhardt, Carsten, Walter, Steffen, Singh, Harpreet, Hwu, Patrick, Yee, Cassian, Andersson, Borje, Tsimberidou, Apostolia-Marie

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Feasibility and Safety of Personalized, Multi-Target, Adoptive Cell Therapy (IMA101): First-in-Human Clinical Trial in Patients with Advanced Metastatic Cancer von Tsimberidou, Apostolia M, Guenther, Kerstin, Andersson, Borje S, Mendrzyk, Regina, Alpert, Amir, Wagner, Claudia, Nowak, Anna, Aslan, Katrin, Satelli, Arun, Richter, Fabian, Kuttruff-Coqui, Sabrina, Schoor, Oliver, Fritsche, Jens, Coughlin, Zoe, Mohamed, Ali S, Sieger, Kerry, Norris, Becky, Ort, Rita, Beck, Jennifer, Vo, Henry Hiep, Hoffgaard, Franziska, Ruh, Manuel, Backert, Linus, Wistuba, Ignacio I, Fuhrmann, David, Ibrahim, Nuhad K, Morris, Van Karlyle, Kee, Bryan K, Halperin, Daniel M, Nogueras-Gonzalez, Graciela M, Kebriaei, Partow, Shpall, Elizabeth J, Vining, David, Hwu, Patrick, Singh, Harpreet, Reinhardt, Carsten, Britten, Cedrik M, Hilf, Norbert, Weinschenk, Toni, Maurer, Dominik, Walter, Steffen

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The non-classical HLA class I molecule HFE does not influence the NK-like activity contained in fresh human PBMCs and does not interact with NK cells von Pascolo, Steve, Ginhoux, Florent, Laham, Nihay, Walter, Steffen, Schoor, Oliver, Probst, Jochen, Rohrlich, Pierre, Obermayr, Florian, Fisch, Paul, Danos, Olivier, Ehrlich, Rachel, Lemonnier, Francois A., Rammensee, Hans-Georg

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IMMU-52. SELECTION OF GLIOMA T-CELL THERAPY TARGETS BASED ON THE ANALYSIS OF TUMOR IMMUNOPEPTIDOME AND EXPRESSION PROFILES von Carrera, Diego, Hayes, Josie, Mueller, Soeren, Shelton, Samuel J, Weinschenk, Toni, Song, Colette, Fritsche, Jens, Schoor, Oliver, Kuttruff-Coqui, Sabrina, Hilf, Norbert, Kohanbash, Gary, Watchmaker, Payal, Oldham, Michael C, Costello, Joseph, Singh, Harpreet, Okada, Hideho

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Publisher Correction: Actively personalized vaccination trial for newly diagnosed glioblastoma von Hilf, Norbert, Kuttruff-Coqui, Sabrina, Frenzel, Katrin, Bukur, Valesca, Stevanović, Stefan, Gouttefangeas, Cecile, Platten, Michael, Tabatabai, Ghazaleh, Dutoit, Valerie, van der Burg, Sjoerd H., Straten, Per thor, Martinez-Ricarte, Francisco, Ponsati, Berta, Okada, Hideho, Lassen, Ulrik, Admon, Arie, Ottensmeier, Christian H., Ulges, Alexander, Kreiter, Sebastian, von Deimling, Andreas, Skardelly, Marco, Migliorini, Denis, Kroep, Judith R., Idorn, Manja, Rodon, Jordi, Piro, Jordi, Poulsen, Hans S., Shraibman, Bracha, McCann, Katy, Mendrzyk, Regina, Lower, Martin, Stieglbauer, Monika, Britten, Cedrik M., Capper, David, Welters, Marij J. P., Sahuquillo, Juan, Kiesel, Katharina, Derhovanessian, Evelyna, Rusch, Elisa, Bunse, Lukas, Song, Colette, Heesch, Sandra, Wagner, Claudia, Kemmer-Bruck, Alexandra, Ludwig, Jorg, Castle, John C., Schoor, Oliver, Tadmor, Arbel D., Green, Edward, Fritsche, Jens, Meyer, Miriam, Pawlowski, Nina, Dorner, Sonja, Hoffgaard, Franziska, Rossler, Bernhard, Maurer, Dominik, Weinschenk, Toni, Reinhardt, Carsten, Huber, Christoph, Rammensee, Hans-Georg, Singh-Jasuja, Harpreet, Sahin, Ugur, Dietrich, Pierre-Yves, Wick, Wolfgang

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Integrated functional genomics approach for the design of patient-individual antitumor vaccines von WEINSCHENK, Toni, GOUTTEFANGEAS, Cécile, STEVANOVIC, Stefan, RAMMENSEE, Hans-Georg, SCHIRLE, Markus, OBERMAYR, Florian, WALTER, Steffen, SCHOOR, Oliver, KUREK, Raffael, LOESER, Wolfgang, BICHLER, Karl-Horst, WERNET, Dorothee

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