Molecular Physiology of Bile Acid Signaling in Health, Disease, and Aging von Perino, Alessia, Demagny, Hadrien, Velazquez-Villegas, Laura, Schoonjans, Kristina

Volltext

TGR5 and Immunometabolism: Insights from Physiology and Pharmacology von Perino, Alessia, Schoonjans, Kristina

Volltext

Mechano-modulatory synthetic niches for liver organoid derivation von Sorrentino, Giovanni, Rezakhani, Saba, Yildiz, Ece, Nuciforo, Sandro, Heim, Markus H., Lutolf, Matthias P., Schoonjans, Kristina

Volltext

TGR5 signalling promotes mitochondrial fission and beige remodelling of white adipose tissue von Velazquez-Villegas, Laura A., Perino, Alessia, Lemos, Vera, Zietak, Marika, Nomura, Mitsunori, Pols, Thijs Willem Hendrik, Schoonjans, Kristina

Volltext

NAD⁺ repletion improves mitochondrial and stem cell function and enhances life span in mice von Zhang, Hongbo, Ryu, Dongryeol, Wu, Yibo, Gariani, Karim, Wang, Xu, Luan, Peiling, D'Amico, Davide, Ropelle, Eduardo R., Lutolf, Matthias P., Aebersold, Ruedi, Schoonjans, Kristina, Menzies, Keir J., Auwerx, Johan

Volltext

The NAD+/Sirtuin Pathway Modulates Longevity through Activation of Mitochondrial UPR and FOXO Signaling von Mouchiroud, Laurent, Houtkooper, Riekelt H., Moullan, Norman, Katsyuba, Elena, Ryu, Dongryeol, Cantó, Carles, Mottis, Adrienne, Jo, Young-Suk, Viswanathan, Mohan, Schoonjans, Kristina, Guarente, Leonard, Auwerx, Johan

Volltext

Hepatic glucose sensing and integrative pathways in the liver von Oosterveer, Maaike H, Schoonjans, Kristina

Volltext

Bile Acids Trigger GLP-1 Release Predominantly by Accessing Basolaterally Located G Protein–Coupled Bile Acid Receptors von Brighton, Cheryl A, Rievaj, Juraj, Kuhre, Rune E, Glass, Leslie L, Schoonjans, Kristina, Holst, Jens J, Gribble, Fiona M, Reimann, Frank

Volltext

The Receptor TGR5 Mediates the Prokinetic Actions of Intestinal Bile Acids and Is Required for Normal Defecation in Mice von Alemi, Farzad, Poole, Daniel P, Chiu, Jonathan, Schoonjans, Kristina, Cattaruzza, Fiore, Grider, John R, Bunnett, Nigel W, Corvera, Carlos U

Volltext

Eliciting the mitochondrial unfolded protein response by nicotinamide adenine dinucleotide repletion reverses fatty liver disease in mice von Gariani, Karim, Menzies, Keir J., Ryu, Dongryeol, Wegner, Casey J., Wang, Xu, Ropelle, Eduardo R., Moullan, Norman, Zhang, Hongbo, Perino, Alessia, Lemos, Vera, Kim, Bohkyung, Park, Young‐Ki, Piersigilli, Alessandra, Pham, Tho X., Yang, Yue, Ku, Chai Siah, Koo, Sung I., Fomitchova, Anna, Cantó, Carlos, Schoonjans, Kristina, Sauve, Anthony A., Lee, Ji‐Young, Auwerx, Johan

Volltext

TGR5 Regulates Macrophage Inflammation in Nonalcoholic Steatohepatitis by Modulating NLRP3 Inflammasome Activation von Shi, Yong, Su, Wantong, Zhang, Lei, Shi, Chengyu, Zhou, Jinren, Wang, Peng, Wang, Hao, Shi, Xiaoli, Wei, Song, Wang, Qi, Auwerx, Johan, Schoonjans, Kristina, Yu, Yue, Pan, Rui, Zhou, Haoming, Lu, Ling

Volltext

TGR5 Activation Inhibits Atherosclerosis by Reducing Macrophage Inflammation and Lipid Loading von Pols, Thijs W.H., Nomura, Mitsunori, Harach, Taoufiq, Lo Sasso, Giuseppe, Oosterveer, Maaike H., Thomas, Charles, Rizzo, Giovanni, Gioiello, Antimo, Adorini, Luciano, Pellicciari, Roberto, Auwerx, Johan, Schoonjans, Kristina

Volltext

Asparagine protects pericentral hepatocytes during acute liver injury von Sun, Yu, Demagny, Hadrien, Faure, Adrien, Pontanari, Francesca, Jalil, Antoine, Bresciani, Nadia, Yildiz, Ece, Korbelius, Melanie, Perino, Alessia, Schoonjans, Kristina

Volltext

SIRT2 deficiency modulates macrophage polarization and susceptibility to experimental colitis von Lo Sasso, Giuseppe, Menzies, Keir Joe, Mottis, Adrienne, Piersigilli, Alessandra, Perino, Alessia, Yamamoto, Hiroyasu, Schoonjans, Kristina, Auwerx, Johan

Volltext

PARP-1 Inhibition Increases Mitochondrial Metabolism through SIRT1 Activation von Bai, Péter, Cantó, Carles, Oudart, Hugues, Brunyánszki, Attila, Cen, Yana, Thomas, Charles, Yamamoto, Hiroyasu, Huber, Aline, Kiss, Borbála, Houtkooper, Riekelt H., Schoonjans, Kristina, Schreiber, Valérie, Sauve, Anthony A., Menissier-de Murcia, Josiane, Auwerx, Johan

Volltext

The Slc25a47 locus is a novel determinant of hepatic mitochondrial function implicated in liver fibrosis von Bresciani, Nadia, Demagny, Hadrien, Lemos, Vera, Pontanari, Francesca, Li, Xiaoxu, Sun, Yu, Li, Hao, Perino, Alessia, Auwerx, Johan, Schoonjans, Kristina

Volltext

The TGR5 receptor mediates bile acid-induced itch and analgesia von Alemi, Farzad, Kwon, Edwin, Poole, Daniel P, Lieu, TinaMarie, Lyo, Victoria, Cattaruzza, Fiore, Cevikbas, Ferda, Steinhoff, Martin, Nassini, Romina, Materazzi, Serena, Guerrero-Alba, Raquel, Valdez-Morales, Eduardo, Cottrell, Graeme S, Schoonjans, Kristina, Geppetti, Pierangelo, Vanner, Stephen J, Bunnett, Nigel W, Corvera, Carlos U

Volltext

The receptor TGR5 protects the liver from bile acid overload during liver regeneration in mice von Péan, Noémie, Doignon, Isabelle, Garcin, Isabelle, Besnard, Aurore, Julien, Boris, Liu, Bingkaï, Branchereau, Sophie, Spraul, Anne, Guettier, Catherine, Humbert, Lydie, Schoonjans, Kristina, Rainteau, Dominique, Tordjmann, Thierry

Volltext

LRH-1: an orphan nuclear receptor involved in development, metabolism and steroidogenesis von Fayard, Elisabeth, Auwerx, Johan, Schoonjans, Kristina

Volltext

Pharmacological Inhibition of Poly(ADP-Ribose) Polymerases Improves Fitness and Mitochondrial Function in Skeletal Muscle von Pirinen, Eija, Cantó, Carles, Jo, Young Suk, Morato, Laia, Zhang, Hongbo, Menzies, Keir J., Williams, Evan G., Mouchiroud, Laurent, Moullan, Norman, Hagberg, Carolina, Li, Wei, Timmers, Silvie, Imhof, Ralph, Verbeek, Jef, Pujol, Aurora, van Loon, Barbara, Viscomi, Carlo, Zeviani, Massimo, Schrauwen, Patrick, Sauve, Anthony A., Schoonjans, Kristina, Auwerx, Johan

Volltext