Targeting DNA Damage Response in Prostate and Breast Cancer von Wengner, Antje M, Scholz, Arne, Haendler, Bernard

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Radium-223 Inhibits Osseous Prostate Cancer Growth by Dual Targeting of Cancer Cells and Bone Microenvironment in Mouse Models von Suominen, Mari I, Fagerlund, Katja M, Rissanen, Jukka P, Konkol, Yvonne M, Morko, Jukka P, Peng, ZhiQi, Alhoniemi, Esa J, Laine, Salla K, Corey, Eva, Mumberg, Dominik, Ziegelbauer, Karl, Käkönen, Sanna-Maria, Halleen, Jussi M, Vessella, Robert L, Scholz, Arne

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Radium-223 mechanism of action: implications for use in treatment combinations von Morris, Michael J., Corey, Eva, Guise, Theresa A., Gulley, James L., Kevin Kelly, William, Quinn, David I., Scholz, Arne, Sgouros, George

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Identification of Atuveciclib (BAY 1143572), the First Highly Selective, Clinical PTEFb/CDK9 Inhibitor for the Treatment of Cancer von Lücking, Ulrich, Scholz, Arne, Lienau, Philip, Siemeister, Gerhard, Kosemund, Dirk, Bohlmann, Rolf, Briem, Hans, Terebesi, Ildiko, Meyer, Kirstin, Prelle, Katja, Denner, Karsten, Bömer, Ulf, Schäfer, Martina, Eis, Knut, Valencia, Ray, Ince, Stuart, von Nussbaum, Franz, Mumberg, Dominik, Ziegelbauer, Karl, Klebl, Bert, Choidas, Axel, Nussbaumer, Peter, Baumann, Matthias, Schultz‐Fademrecht, Carsten, Rühter, Gerd, Eickhoff, Jan, Brands, Michael

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Regorafenib (BAY 73‐4506): Antitumor and antimetastatic activities in preclinical models of colorectal cancer von Schmieder, Roberta, Hoffmann, Jens, Becker, Michael, Bhargava, Ajay, Müller, Tina, Kahmann, Nicole, Ellinghaus, Peter, Adams, Robert, Rosenthal, André, Thierauch, Karl‐Heinz, Scholz, Arne, Wilhelm, Scott M., Zopf, Dieter

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The Mode-of-Action of Targeted Alpha Therapy Radium-223 as an Enabler for Novel Combinations to Treat Patients with Bone Metastasis von Suominen, Mari I, Wilson, Timothy, Käkönen, Sanna-Maria, Scholz, Arne

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Atu027, a liposomal small interfering RNA formulation targeting protein kinase N3, inhibits cancer progression von Aleku, Manuela, Schulz, Petra, Keil, Oliver, Santel, Ansgar, Schaeper, Ute, Dieckhoff, Britta, Janke, Oliver, Endruschat, Jens, Durieux, Birgit, Röder, Nadine, Löffler, Kathrin, Lange, Christian, Fechtner, Melanie, Möpert, Kristin, Fisch, Gerald, Dames, Sibylle, Arnold, Wolfgang, Jochims, Karin, Giese, Klaus, Wiedenmann, Bertram, Scholz, Arne, Kaufmann, Jörg

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Enhanced Antitumor Efficacy of Radium-223 and Enzalutamide in the Intratibial LNCaP Prostate Cancer Model von Suominen, Mari I, Knuuttila, Matias, Schatz, Christoph A, Schlicker, Andreas, Vääräniemi, Jukka, Sjöholm, Birgitta, Alhoniemi, Esa, Haendler, Bernard, Mumberg, Dominik, Käkönen, Sanna-Maria, Scholz, Arne

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Acetyl-CoA carboxylase inhibitors attenuate WNT and Hedgehog signaling and suppress pancreatic tumor growth von Petrova, Elissaveta, Scholz, Arne, Paul, Juliane, Sturz, Andrea, Haike, Katja, Siegel, Franziska, Mumberg, Dominik, Liu, Ningshu

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The Targeted Immunocytokine L19-IL2 Efficiently Inhibits the Growth of Orthotopic Pancreatic Cancer von WAGNER, Karola, SCHULZ, Petra, SCHOLZ, Arne, WIEDENMANN, Bertram, MENRAD, Andreas

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Cyclin-dependent kinase 9 as a potential specific molecular target in NK cell leukemia/lymphoma von Kinoshita, Shiori, Ishida, Takashi, Ito, Asahi, Narita, Tomoko, Masaki, Ayako, Suzuki, Susumu, Yoshida, Takashi, Ri, Masaki, Kusumoto, Shigeru, Komatsu, Hirokazu, Shimizu, Norio, Inagaki, Hiroshi, Kuroda, Taruho, Scholz, Arne, Ueda, Ryuzo, Sanda, Takaomi, Iida, Shinsuke

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Additive Benefits of Radium-223 Dichloride and Bortezomib Combination in a Systemic Multiple Myeloma Mouse Model von Suominen, Mari I., Mäki-Jouppila, Jenni, Huhtinen, Anna, Sjöholm, Birgitta, Rissanen, Jukka P., Luostarinen, Anniina, Fagerlund, Katja M., Alhoniemi, Esa, Siemeister, Gerhard, Mumberg, Dominik, Käkönen, Sanna-Maria, Scholz, Arne

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Allosteric MEK1/2 Inhibitor Refametinib (BAY 86-9766) in Combination with Sorafenib Exhibits Antitumor Activity in Preclinical Murine and Rat Models of Hepatocellular Carcinoma von Schmieder, Roberta, Puehler, Florian, Neuhaus, Roland, Kissel, Maria, Adjei, Alex A, Miner, Jeffrey N, Mumberg, Dominik, Ziegelbauer, Karl, Scholz, Arne

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Targeted thorium-227 conjugates as treatment options in oncology von Karlsson, Jenny, Schatz, Christoph A, Wengner, Antje M, Hammer, Stefanie, Scholz, Arne, Cuthbertson, Alan, Wagner, Volker, Hennekes, Hartwig, Jardine, Vicki, Hagemann, Urs B

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Angiopoietin-2 Promotes Disease Progression of Neuroendocrine Tumors von Detjen, Katharina M, Rieke, Svenja, Deters, Antje, Schulz, Petra, Rexin, Annett, Vollmer, Sonja, Hauff, Peter, Wiedenmann, Bertram, Pavel, Marianne, Scholz, Arne

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Activated signal transducer and activator of transcription 3 (STAT3) supports the malignant phenotype of human pancreatic cancer von Scholz, Arne, Heinze, Sandra, Detjen, Katharina M, Peters, Michael, Welzel, Martina, Hauff, Peter, Schirner, Michael, Wiedenmann, Bertram, Rosewicz, Stefan

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Abstract 3022: BAY 1143572, a first-in-class, highly selective, potent and orally available inhibitor of PTEFb/CDK9 currently in Phase I, shows convincing anti-tumor activity in pr... von Scholz, Arne, Oellerich, Thomas, Hussain, Akhtar, Lindner, Sarah, Luecking, Ulrich, Walter, Annette O., Ellinghaus, Peter, Valencia, Ray, von Nussbaum, Franz, Mumberg, Dominik, Brands, Michael, Ince, Stuart, Serve, Hubert, Ziegelbauer, Karl

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Microvessel density correlates with lymph node metastases and prognosis in hilar cholangiocarcinoma von Thelen, Armin, Scholz, Arne, Benckert, Christoph, Schröder, Maik, Weichert, Wilko, Wiedenmann, Bertram, Neuhaus, Peter, Jonas, Sven

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Abstract A44: 18F-FLT, a potential biomarker for predicting the synergistic combination of PI3K inhibitor BAY 80-6946 and MEK inhibitor BAY 86-9766 von Berndorff, Dietmar, Mueller, Andre Mueller, Haegebarth, Andrea, Berndt, Mathias, Scholz, Arne Scholz, Puehler, Florian, Liu, Ningshu

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Abstract 1393: PSMA-Targeted Thorium Conjugate (BAY 2315497) and olaparib combination show synergistic anti-tumor activity in prostate cancer models von Schatz, Christoph A., Hammer, Stefanie, Wengner, Antje, Hagemann, Urs B., Mumberg, Dominik, Scholz, Arne

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