Genome instability in multiple myeloma von Neuse, Carl Jannes, Lomas, Oliver C., Schliemann, Christoph, Shen, Yu Jia, Manier, Salomon, Bustoros, Mark, Ghobrial, Irene M.

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The beginning of the end for conventional RECIST — novel therapies require novel imaging approaches von Gerwing, Mirjam, Herrmann, Ken, Helfen, Anne, Schliemann, Christoph, Berdel, Wolfgang E., Eisenblätter, Michel, Wildgruber, Moritz

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Adrenomedullin-CALCRL axis controls relapse-initiating drug tolerant acute myeloid leukemia cells von Larrue, Clément, Guiraud, Nathan, Mouchel, Pierre-Luc, Dubois, Marine, Farge, Thomas, Gotanègre, Mathilde, Bosc, Claudie, Saland, Estelle, Nicolau-Travers, Marie-Laure, Sabatier, Marie, Serhan, Nizar, Sahal, Ambrine, Boet, Emeline, Mouche, Sarah, Heydt, Quentin, Aroua, Nesrine, Stuani, Lucille, Kaoma, Tony, Angenendt, Linus, Mikesch, Jan-Henrik, Schliemann, Christoph, Vergez, François, Tamburini, Jérôme, Récher, Christian, Sarry, Jean-Emmanuel

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Chromosomal Abnormalities and Prognosis in NPM1 -Mutated Acute Myeloid Leukemia: A Pooled Analysis of Individual Patient Data From Nine International Cohorts von Angenendt, Linus, Röllig, Christoph, Montesinos, Pau, Martínez-Cuadrón, David, Barragan, Eva, García, Raimundo, Botella, Carmen, Martínez, Pilar, Ravandi, Farhad, Kadia, Tapan, Kantarjian, Hagop M, Cortes, Jorge, Juliusson, Gunnar, Lazarevic, Vladimir, Höglund, Martin, Lehmann, Sören, Recher, Christian, Pigneux, Arnaud, Bertoli, Sarah, Dumas, Pierre-Yves, Dombret, Hervé, Preudhomme, Claude, Micol, Jean-Baptiste, Terré, Christine, Ráčil, Zdeněk, Novák, Jan, Žák, Pavel, Wei, Andrew H, Tiong, Ing S, Wall, Meaghan, Estey, Elihu, Shaw, Carole, Exeler, Rita, Wagenführ, Lisa, Stölzel, Friedrich, Thiede, Christian, Stelljes, Matthias, Lenz, Georg, Mikesch, Jan-Henrik, Serve, Hubert, Ehninger, Gerhard, Berdel, Wolfgang E, Kramer, Michael, Krug, Utz, Schliemann, Christoph

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A proof of concept phase I/II pilot trial of LSD1 inhibition by tranylcypromine combined with ATRA in refractory/relapsed AML patients not eligible for intensive therapy von Wass, Maxi, Göllner, Stefanie, Besenbeck, Birgit, Schlenk, Richard F., Mundmann, Petra, Göthert, Joachim R., Noppeney, Richard, Schliemann, Christoph, Mikesch, Jan-Henrik, Lenz, Georg, Dugas, Martin, Wermke, Martin, Röllig, Christoph, Bornhäuser, Martin, Serve, Hubert, Platzbecker, Uwe, Foerster, Kathrin I., Burhenne, Jürgen, Haefeli, Walter E., Müller, Lutz P., Binder, Mascha, Pabst, Caroline, Müller-Tidow, Carsten

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PD-1 and PD-L1 Expression in NSCLC Indicate a Favorable Prognosis in Defined Subgroups von Schmidt, Lars Henning, Kümmel, Andreas, Görlich, Dennis, Mohr, Michael, Bröckling, Sebastian, Mikesch, Jan Henrik, Grünewald, Inga, Marra, Alessandro, Schultheis, Anne M, Wardelmann, Eva, Müller-Tidow, Carsten, Spieker, Tilmann, Schliemann, Christoph, Berdel, Wolfgang E, Wiewrodt, Rainer, Hartmann, Wolfgang

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Integrated RNAi screening identifies the NEDDylation pathway as a synergistic partner of azacytidine in acute myeloid leukemia von Klosner, Justine, Agelopoulos, Konstantin, Rohde, Christian, Göllner, Stefanie, Schliemann, Christoph, Berdel, Wolfgang E., Müller-Tidow, Carsten

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Real-world experience of CPX-351 as first-line treatment for patients with acute myeloid leukemia von Rautenberg, Christina, Stölzel, Friedrich, Röllig, Christoph, Stelljes, Matthias, Gaidzik, Verena, Lauseker, Michael, Kriege, Oliver, Verbeek, Mareike, Unglaub, Julia Marie, Thol, Felicitas, Krause, Stefan W., Hänel, Mathias, Neuerburg, Charlotte, Vucinic, Vladan, Jehn, Christian-Friedrich, Severmann, Julia, Wass, Maxi, Fransecky, Lars, Chemnitz, Jens, Holtick, Udo, Schäfer-Eckart, Kerstin, Schröder, Josephine, Kraus, Sabrina, Krüger, William, Kaiser, Ulrich, Scholl, Sebastian, Koch, Kathrin, Henning, Lea, Kobbe, Guido, Haas, Rainer, Alakel, Nael, Röhnert, Maximilian-Alexander, Sockel, Katja, Hanoun, Maher, Platzbecker, Uwe, Holderried, Tobias A. W., Morgner, Anke, Heuser, Michael, Sauer, Tim, Götze, Katharina S., Wagner-Drouet, Eva, Döhner, Konstanze, Döhner, Hartmut, Schliemann, Christoph, Schetelig, Johannes, Bornhäuser, Martin, Germing, Ulrich, Schroeder, Thomas, Middeke, Jan Moritz

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SAMHD1 is a biomarker for cytarabine response and a therapeutic target in acute myeloid leukemia von Schneider, Constanze, Oellerich, Thomas, Baldauf, Hanna-Mari, Schwarz, Sarah-Marie, Thomas, Dominique, Flick, Robert, Bohnenberger, Hanibal, Kaderali, Lars, Stegmann, Lena, Cremer, Anjali, Martin, Margarethe, Lohmeyer, Julian, Michaelis, Martin, Hornung, Veit, Schliemann, Christoph, Berdel, Wolfgang E, Hartmann, Wolfgang, Wardelmann, Eva, Comoglio, Federico, Hansmann, Martin-Leo, Yakunin, Alexander F, Geisslinger, Gerd, Ströbel, Philipp, Ferreirós, Nerea, Serve, Hubert, Keppler, Oliver T, Cinatl, Jindrich

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Future Options of Molecular-Targeted Therapy in Small Cell Lung Cancer von Schulze, Arik Bernard, Evers, Georg, Kerkhoff, Andrea, Mohr, Michael, Schliemann, Christoph, Berdel, Wolfgang E, Schmidt, Lars Henning

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Upstream open reading frames regulate translation of cancer-associated transcripts and encode HLA-presented immunogenic tumor antigens von Nelde, Annika, Flötotto, Lea, Jürgens, Lara, Szymik, Laura, Hubert, Elvira, Bauer, Jens, Schliemann, Christoph, Kessler, Torsten, Lenz, Georg, Rammensee, Hans-Georg, Walz, Juliane S., Wethmar, Klaus

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Selective inactivation of hypomethylating agents by SAMHD1 provides a rationale for therapeutic stratification in AML von Oellerich, Thomas, Schneider, Constanze, Thomas, Dominique, Knecht, Kirsten M., Buzovetsky, Olga, Kaderali, Lars, Schliemann, Christoph, Bohnenberger, Hanibal, Angenendt, Linus, Hartmann, Wolfgang, Wardelmann, Eva, Rothenburger, Tamara, Mohr, Sebastian, Scheich, Sebastian, Comoglio, Federico, Wilke, Anne, Ströbel, Philipp, Serve, Hubert, Michaelis, Martin, Ferreirós, Nerea, Geisslinger, Gerd, Xiong, Yong, Keppler, Oliver T., Cinatl, Jindrich

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Prediction of complete remission and survival in acute myeloid leukemia using supervised machine learning von Eckardt, Jan-Niklas, Röllig, Christoph, Metzeler, Klaus, Kramer, Michael, Stasik, Sebastian, Georgi, Julia-Annabell, Heisig, Peter, Spiekermann, Karsten, Krug, Utz, Braess, Jan, Görlich, Dennis, Sauerland, Cristina M, Woermann, Bernhard, Herold, Tobias, Berdel, Wolfgang E, Hiddemann, Wolfgang, Kroschinsky, Frank, Schetelig, Johannes, Platzbecker, Uwe, Müller-Tidow, Carsten, Sauer, Tim, Serve, Hubert, Baldus, Claudia, Schäfer-Eckart, Kerstin, Kaufmann, Martin, Krause, Stefan, Hänel, Mathias, Schliemann, Christoph, Hanoun, Maher, Thiede, Christian, Bornhäuser, Martin, Wendt, Karsten, Middeke, Jan Moritz

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Prostate specific membrane antigen (PSMA) expression in non-small cell lung cancer von Schmidt, Lars Henning, Heitkötter, Birthe, Schulze, Arik B, Schliemann, Christoph, Steinestel, Konrad, Trautmann, Marcel, Marra, Alessandro, Hillejan, Ludger, Mohr, Michael, Evers, Georg, Wardelmann, Eva, Rahbar, Kambiz, Görlich, Dennis, Lenz, Georg, Berdel, Wolfgang E, Hartmann, Wolfgang, Wiewrodt, Rainer, Huss, Sebastian

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EZH2 mutations and impact on clinical outcome: an analysis in 1,604 patients with newly diagnosed acute myeloid leukemia von Stasik, Sebastian, Middeke, Jan M, Kramer, Michael, Röllig, Christoph, Krämer, Alwin, Scholl, Sebastian, Hochhaus, Andreas, Crysandt, Martina, Brümmendorf, Tim H, Naumann, Ralph, Steffen, Björn, Kunzmann, Volker, Einsele, Hermann, Schaich, Markus, Burchert, Andreas, Neubauer, Andreas, Schäfer-Eckart, Kerstin, Schliemann, Christoph, Krause, Stefan, Herbst, Regina, Hänel, Mathias, Frickhofen, Norbert, Noppeney, Richard, Kaiser, Ulrich, Baldus, Claudia D, Kaufmann, Martin, Rácil, Zdenek, Platzbecker, Uwe, Berdel, Wolfgang E, Mayer, Jiri, Serve, Hubert, Müller-Tidow, Carsten, Ehninger, Gerhard, Bornhäuser, Martin, Schetelig, Johannes, Thiede, Christian

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Time from diagnosis to treatment has no impact on survival in newly diagnosed acute myeloid leukemia treated with venetoclax-based regimens von Baden, David, Zukunft, Sven, Hernandez, Gema, Wolgast, Nadine, Steinhauser, Sophie, Pohlmann, Alexander, Schliemann, Christoph, Mikesch, Jan-Henrik, Steffen, Bjorn, Sauer, Tim, Hanoun, Maher, Schafer-Eckart, Kerstin, Krause, Stefan W, Hanel, Mathias, Einsele, Hermann, Jost, Edgar, Brummendorf, Tim H, Scholl, Sebastian, Hochhaus, Andreas, Neubauer, Andreas, Burchert, Andreas, Kaufmann, Martin, Niemann, Dirk, Schaich, Markus, Blau, Wolfgang, Kiani, Alexander, Gorner, Martin, Kaiser, Ulrich, Kullmer, Johannes, Weber, Thomas, Berdel, Wolfgang E, Ehninger, Gerhard, Muller-Tidow, Carsten, Platzbecker, Uwe, Serve, Hubert, Bornhauser, Martin, Rollig, Christoph, Baldus, Claudia D, Fransecky, Lars

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An open-label, phase I/II trial to determine the maximum tolerated dose and investigate safety, pharmacokinetics and efficacy of BI 836858, an unconjugated anti-CD33 monoclonal ant... von Fiedler, Walter, Montesinos, Pau, Schliemann, Christoph, Middeke, Jan, Vasu, Sumithira, Scholz, Christian W, Esteve, Jordi, Mondal, Shoubhik, Rüter, Björn, Burkard, Ute, Osswald, Annika, Blum, William

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UBTF tandem duplications are rare but recurrent alterations in adult AML and associated with younger age, myelodysplasia, and inferior outcome von Georgi, Julia-Annabell, Stasik, Sebastian, Eckardt, Jan-Niklas, Zukunft, Sven, Hartwig, Marita, Röllig, Christoph, Middeke, Jan Moritz, Oelschlägel, Uta, Krug, Utz, Sauer, Tim, Scholl, Sebastian, Hochhaus, Andreas, Brümmendorf, Tim H., Naumann, Ralph, Steffen, Björn, Einsele, Hermann, Schaich, Markus, Burchert, Andreas, Neubauer, Andreas, Schäfer-Eckart, Kerstin, Schliemann, Christoph, Krause, Stefan W., Hänel, Mathias, Noppeney, Richard, Kaiser, Ulrich, Baldus, Claudia D., Kaufmann, Martin, Müller-Tidow, Carsten, Platzbecker, Uwe, Berdel, Wolfgang E., Serve, Hubert, Ehninger, Gerhard, Bornhäuser, Martin, Schetelig, Johannes, Kroschinsky, Frank, Thiede, Christian

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Molecular profiling and clinical implications of patients with acute myeloid leukemia and extramedullary manifestations von Eckardt, Jan-Niklas, Stölzel, Friedrich, Kunadt, Desiree, Röllig, Christoph, Stasik, Sebastian, Wagenführ, Lisa, Jöhrens, Korinna, Kuithan, Friederike, Krämer, Alwin, Scholl, Sebastian, Hochhaus, Andreas, Crysandt, Martina, Brümmendorf, Tim H, Naumann, Ralph, Steffen, Björn, Kunzmann, Volker, Einsele, Hermann, Schaich, Markus, Burchert, Andreas, Neubauer, Andreas, Schäfer-Eckart, Kerstin, Schliemann, Christoph, Krause, Stefan W, Herbst, Regina, Hänel, Mathias, Hanoun, Maher, Kaiser, Ulrich, Kaufmann, Martin, Rácil, Zdenek, Mayer, Jiri, Kroschinsky, Frank, Berdel, Wolfgang E, Ehninger, Gerhard, Serve, Hubert, Müller-Tidow, Carsten, Platzbecker, Uwe, Baldus, Claudia D, Schetelig, Johannes, Bornhäuser, Martin, Thiede, Christian, Middeke, Jan Moritz

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Randomized phase III GnG study on two schedules of gemtuzumab ozogamicin as adjunct to intensive induction therapy and double-blinded intensive postremission therapy with or withou... von Jaramillo, Sonia, Krisam, Johannes, Le Cornet, Lucian, Kratzmann, Markus, Baumann, Lukas, Eissymont, Olga, Crysandt, Martina, Görner, Martin, Kayser, Sabine, Krause, Stefan, Schliemann, Christoph, Gaska, Tobias, Kaufmann, Martin, Chemnitz, Jens, Schaich, Markus, Hoellein, Alexander, Platzbecker, Uwe, Kieser, Meinhard, Müller-Tidow, Carsten, Schlenk, Richard F

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