FAK in cancer: mechanistic findings and clinical applications von Sulzmaier, Florian J., Jean, Christine, Schlaepfer, David D.

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Focal adhesion kinase signaling in unexpected places von Kleinschmidt, Elizabeth G, Schlaepfer, David D

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Targeting FAK in anticancer combination therapies von Dawson, John C., Serrels, Alan, Stupack, Dwayne G., Schlaepfer, David D., Frame, Margaret C.

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Focal adhesion kinase: in command and control of cell motility von Schlaepfer, David D, Mitra, Satyajit K, Hanson, Daniel A

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VEGF-Induced Vascular Permeability Is Mediated by FAK von Chen, Xiao Lei, Nam, Ju-Ock, Jean, Christine, Lawson, Christine, Walsh, Colin T., Goka, Erik, Lim, Ssang-Taek, Tomar, Alok, Tancioni, Isabelle, Uryu, Sean, Guan, Jun-Lin, Acevedo, Lisette M., Weis, Sara M., Cheresh, David A., Schlaepfer, David D.

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Focal adhesion kinase: switching between GAPs and GEFs in the regulation of cell motility von Tomar, Alok, Schlaepfer, David D

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Inhibition of endothelial FAK activity prevents tumor metastasis by enhancing barrier function von Jean, Christine, Chen, Xiao Lei, Nam, Ju-Ock, Tancioni, Isabelle, Uryu, Sean, Lawson, Christine, Ward, Kristy K, Walsh, Colin T, Miller, Nichol L G, Ghassemian, Majid, Turowski, Patric, Dejana, Elisabetta, Weis, Sara, Cheresh, David A, Schlaepfer, David D

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Integrin-regulated FAK–Src signaling in normal and cancer cells von Mitra, Satyajit K, Schlaepfer, David D

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Cortactin as a target for FAK in the regulation of focal adhesion dynamics von Tomar, Alok, Lawson, Christine, Ghassemian, Majid, Schlaepfer, David D

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Myosin II activity regulates vinculin recruitment to focal adhesions through FAK-mediated paxillin phosphorylation von Pasapera, Ana M, Schneider, Ian C, Rericha, Erin, Schlaepfer, David D, Waterman, Clare M

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Focal adhesion kinase signaling - tumor vulnerabilities and clinical opportunities von Schlaepfer, David D, Ojalill, Marjaana, Stupack, Dwayne G

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Autophagy gene haploinsufficiency drives chromosome instability, increases migration, and promotes early ovarian tumors von Delaney, Joe R., Patel, Chandni B., Bapat, Jaidev, Jones, Christian M., Ramos-Zapatero, Maria, Ortell, Katherine K., Tanios, Ralph, Haghighiabyaneh, Mina, Axelrod, Joshua, DeStefano, John W., Tancioni, Isabelle, Schlaepfer, David D., Harismendy, Olivier, La Spada, Albert R., Stupack, Dwayne G.

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A Platform of Synthetic Lethal Gene Interaction Networks Reveals that the GNAQ Uveal Melanoma Oncogene Controls the Hippo Pathway through FAK von Feng, Xiaodong, Arang, Nadia, Rigiracciolo, Damiano Cosimo, Lee, Joo Sang, Yeerna, Huwate, Wang, Zhiyong, Lubrano, Simone, Kishore, Ayush, Pachter, Jonathan A., König, Gabriele M., Maggiolini, Marcello, Kostenis, Evi, Schlaepfer, David D., Tamayo, Pablo, Chen, Qianming, Ruppin, Eytan, Gutkind, J. Silvio

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Genotype tunes pancreatic ductal adenocarcinoma tissue tension to induce matricellular fibrosis and tumor progression von Laklai, Hanane, Miroshnikova, Yekaterina A, Pickup, Michael W, Collisson, Eric A, Kim, Grace E, Barrett, Alex S, Hill, Ryan C, Lakins, Johnathon N, Schlaepfer, David D, Mouw, Janna K, LeBleu, Valerie S, Roy, Nilotpal, Novitskiy, Sergey V, Johansen, Julia S, Poli, Valeria, Kalluri, Raghu, Iacobuzio-Donahue, Christine A, Wood, Laura D, Hebrok, Matthias, Hansen, Kirk, Moses, Harold L, Weaver, Valerie M

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Force-FAK signaling coupling at individual focal adhesions coordinates mechanosensing and microtissue repair von Zhou, Dennis W., Fernández-Yagüe, Marc A., Holland, Elijah N., García, Andrés F., Castro, Nicolas S., O’Neill, Eric B., Eyckmans, Jeroen, Chen, Christopher S., Fu, Jianping, Schlaepfer, David D., García, Andrés J.

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FAK/PYK2 promotes the Wnt/β-catenin pathway and intestinal tumorigenesis by phosphorylating GSK3β von Gao, Chenxi, Chen, Guangming, Kuan, Shih-Fan, Zhang, Dennis Han, Schlaepfer, David D, Hu, Jing

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FAK promotes recruitment of talin to nascent adhesions to control cell motility von Lawson, Christine, Lim, Ssang-Taek, Uryu, Sean, Chen, Xiao Lei, Calderwood, David A, Schlaepfer, David D

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FAK activity in cancer‐associated fibroblasts is a prognostic marker and a druggable key metastatic player in pancreatic cancer von Zaghdoudi, Sonia, Decaup, Emilie, Belhabib, Ismahane, Samain, Rémi, Cassant‐Sourdy, Stéphanie, Rochotte, Julia, Brunel, Alexia, Schlaepfer, David, Cros, Jérome, Neuzillet, Cindy, Strehaiano, Manon, Alard, Amandine, Tomasini, Richard, Rajeeve, Vinothini, Perraud, Aurélie, Mathonnet, Muriel, Pearce, Oliver MT, Martineau, Yvan, Pyronnet, Stéphane, Bousquet, Corinne, Jean, Christine

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Multiple connections link FAK to cell motility and invasion von Schlaepfer, David D, Mitra, Satyajit K

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Nuclear Focal Adhesion Kinase Controls Vascular Smooth Muscle Cell Proliferation and Neointimal Hyperplasia Through GATA4-Mediated Cyclin D1 Transcription von Jeong, Kyuho, Kim, Jung-Hyun, Murphy, James M, Park, Hyeonsoo, Kim, Su-Jeong, Rodriguez, Yelitza A.R, Kong, Hyunkyung, Choi, Chungsik, Guan, Jun-Lin, Taylor, Joan M, Lincoln, Thomas M, Gerthoffer, William T, Kim, Jun-Sub, Ahn, Eun-Young Erin, Schlaepfer, David D, Lim, Ssang-Taek Steve

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