Introduction: Drug Resistance von Kurt Yilmaz, Nese, Schiffer, Celia A

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The molecular basis of drug resistance against hepatitis C virus NS3/4A protease inhibitors von Romano, Keith P, Ali, Akbar, Aydin, Cihan, Soumana, Djade, Ozen, Ayşegül, Deveau, Laura M, Silver, Casey, Cao, Hong, Newton, Alicia, Petropoulos, Christos J, Huang, Wei, Schiffer, Celia A

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Improving Viral Protease Inhibitors to Counter Drug Resistance von Kurt Yilmaz, Nese, Swanstrom, Ronald, Schiffer, Celia A

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APOBEC3s: DNA‐editing human cytidine deaminases von Silvas, Tania V., Schiffer, Celia A.

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Defining the substrate envelope of SARS-CoV-2 main protease to predict and avoid drug resistance von Shaqra, Ala M., Zvornicanin, Sarah N., Huang, Qiu Yu J., Lockbaum, Gordon J., Knapp, Mark, Tandeske, Laura, Bakan, David T., Flynn, Julia, Bolon, Daniel N. A., Moquin, Stephanie, Dovala, Dustin, Kurt Yilmaz, Nese, Schiffer, Celia A.

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HIV-1 VIF and human APOBEC3G interaction directly observed through molecular specific labeling using a new dual promotor vector von Myint, Wazo, Schiffer, Celia A., Matsuo, Hiroshi

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Interactions of APOBEC3s with DNA and RNA von Maiti, Atanu, Hou, Shurong, Schiffer, Celia A, Matsuo, Hiroshi

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Crystal Structure of SARS-CoV-2 Main Protease in Complex with the Non-Covalent Inhibitor ML188 von Lockbaum, Gordon J, Reyes, Archie C, Lee, Jeong Min, Tilvawala, Ronak, Nalivaika, Ellen A, Ali, Akbar, Kurt Yilmaz, Nese, Thompson, Paul R, Schiffer, Celia A

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Comprehensive fitness landscape of SARS-CoV-2 Mpro reveals insights into viral resistance mechanisms von Flynn, Julia M, Samant, Neha, Schneider-Nachum, Gily, Barkan, David T, Yilmaz, Nese Kurt, Schiffer, Celia A, Moquin, Stephanie A, Dovala, Dustin, Bolon, Daniel NA

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Crystal structure of APOBEC3A bound to single-stranded DNA reveals structural basis for cytidine deamination and specificity von Kouno, Takahide, Silvas, Tania V., Hilbert, Brendan J., Shandilya, Shivender M. D., Bohn, Markus F., Kelch, Brian A., Royer, William E., Somasundaran, Mohan, Kurt Yilmaz, Nese, Matsuo, Hiroshi, Schiffer, Celia A.

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Structural basis of substrate specificity in human cytidine deaminase family APOBEC3s von Hou, Shurong, Lee, Jeong Min, Myint, Wazo, Matsuo, Hiroshi, Kurt Yilmaz, Nese, Schiffer, Celia A.

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Deciphering Complex Mechanisms of Resistance and Loss of Potency through Coupled Molecular Dynamics and Machine Learning von Leidner, Florian, Kurt Yilmaz, Nese, Schiffer, Celia A

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Crystal structure of the catalytic domain of HIV-1 restriction factor APOBEC3G in complex with ssDNA von Maiti, Atanu, Myint, Wazo, Kanai, Tapan, Delviks-Frankenberry, Krista, Sierra Rodriguez, Christina, Pathak, Vinay K., Schiffer, Celia A., Matsuo, Hiroshi

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The ssDNA Mutator APOBEC3A Is Regulated by Cooperative Dimerization von Bohn, Markus-Frederik, Shandilya, Shivender M D, Silvas, Tania V, Nalivaika, Ellen A, Kouno, Takahide, Kelch, Brian A, Ryder, Sean P, Kurt-Yilmaz, Nese, Somasundaran, Mohan, Schiffer, Celia A

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Influenza virus drug resistance: a time-sampled population genetics perspective von Foll, Matthieu, Poh, Yu-Ping, Renzette, Nicholas, Ferrer-Admetlla, Anna, Bank, Claudia, Shim, Hyunjin, Malaspinas, Anna-Sapfo, Ewing, Gregory, Liu, Ping, Wegmann, Daniel, Caffrey, Daniel R, Zeldovich, Konstantin B, Bolon, Daniel N, Wang, Jennifer P, Kowalik, Timothy F, Schiffer, Celia A, Finberg, Robert W, Jensen, Jeffrey D

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Deciphering Antifungal Drug Resistance in Pneumocystis jirovecii DHFR with Molecular Dynamics and Machine Learning von Leidner, Florian, Kurt Yilmaz, Nese, Schiffer, Celia A

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Drug resistance against HCV NS3/4A inhibitors is defined by the balance of substrate recognition versus inhibitor binding von Romano, Keith P., Ali, Akbar, Royer, William E., Schiffer, Celia A., Coffin, John M.

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Target-Specific Prediction of Ligand Affinity with Structure-Based Interaction Fingerprints von Leidner, Florian, Kurt Yilmaz, Nese, Schiffer, Celia A

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Non-canonical pattern recognition of a pathogen-derived metabolite by a nuclear hormone receptor identifies virulent bacteria in C. elegans von Peterson, Nicholas D., Tse, Samantha Y., Huang, Qiuyu Judy, Wani, Khursheed A., Schiffer, Celia A., Pukkila-Worley, Read

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Structure of the catalytically active APOBEC3G bound to a DNA oligonucleotide inhibitor reveals tetrahedral geometry of the transition state von Maiti, Atanu, Hedger, Adam K., Myint, Wazo, Balachandran, Vanivilasini, Watts, Jonathan K., Schiffer, Celia A., Matsuo, Hiroshi

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