RosettaAntibodyDesign (RAbD): A general framework for computational antibody design von Adolf-Bryfogle, Jared, Kalyuzhniy, Oleks, Kubitz, Michael, Weitzner, Brian D, Hu, Xiaozhen, Adachi, Yumiko, Schief, William R, Dunbrack, Jr, Roland L

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Multifaceted Effects of Antigen Valency on B Cell Response Composition and Differentiation In Vivo von Kato, Yu, Abbott, Robert K., Freeman, Brian L., Haupt, Sonya, Groschel, Bettina, Silva, Murillo, Menis, Sergey, Irvine, Darrell J., Schief, William R., Crotty, Shane

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Role of nanoscale antigen organization on B-cell activation probed using DNA origami von Veneziano, Rémi, Moyer, Tyson J., Stone, Matthew B., Wamhoff, Eike-Christian, Read, Benjamin J., Mukherjee, Sayak, Shepherd, Tyson R., Das, Jayajit, Schief, William R., Irvine, Darrell J., Bathe, Mark

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RosettaRemodel: a generalized framework for flexible backbone protein design von Huang, Po-Ssu, Ban, Yih-En Andrew, Richter, Florian, Andre, Ingemar, Vernon, Robert, Schief, William R, Baker, David

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Lipid interactions and angle of approach to the HIV-1 viral membrane of broadly neutralizing antibody 10E8: Insights for vaccine and therapeutic design von Irimia, Adriana, Serra, Andreia M, Sarkar, Anita, Jacak, Ronald, Kalyuzhniy, Oleksandr, Sok, Devin, Saye-Francisco, Karen L, Schiffner, Torben, Tingle, Ryan, Kubitz, Michael, Adachi, Yumiko, Stanfield, Robyn L, Deller, Marc C, Burton, Dennis R, Schief, William R, Wilson, Ian A

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Innate immune recognition of glycans targets HIV nanoparticle immunogens to germinal centers von Tokatlian, Talar, Read, Benjamin J., Jones, Christopher A., Kulp, Daniel W., Menis, Sergey, Chang, Jason Y. H., Steichen, Jon M., Kumari, Sudha, Allen, Joel D., Dane, Eric L., Liguori, Alessia, Sangesland, Maya, Lingwood, Daniel, Crispin, Max, Schief, William R., Irvine, Darrell J.

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Slow Delivery Immunization Enhances HIV Neutralizing Antibody and Germinal Center Responses via Modulation of Immunodominance von Cirelli, Kimberly M., Carnathan, Diane G., Nogal, Bartek, Martin, Jacob T., Rodriguez, Oscar L., Upadhyay, Amit A., Enemuo, Chiamaka A., Gebru, Etse H., Choe, Yury, Viviano, Federico, Nakao, Catherine, Pauthner, Matthias G., Reiss, Samantha, Cottrell, Christopher A., Smith, Melissa L., Bastidas, Raiza, Gibson, William, Wolabaugh, Amber N., Melo, Mariane B., Cossette, Benjamin, Kumar, Venkatesh, Patel, Nirav B., Tokatlian, Talar, Menis, Sergey, Kulp, Daniel W., Burton, Dennis R., Murrell, Ben, Schief, William R., Bosinger, Steven E., Ward, Andrew B., Watson, Corey T., Silvestri, Guido, Irvine, Darrell J., Crotty, Shane

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Holes in the Glycan Shield of the Native HIV Envelope Are a Target of Trimer-Elicited Neutralizing Antibodies von McCoy, Laura E., van Gils, Marit J., Ozorowski, Gabriel, Messmer, Terrence, Briney, Bryan, Voss, James E., Kulp, Daniel W., Macauley, Matthew S., Sok, Devin, Pauthner, Matthias, Menis, Sergey, Cottrell, Christopher A., Torres, Jonathan L., Hsueh, Jessica, Schief, William R., Wilson, Ian A., Ward, Andrew B., Sanders, Rogier W., Burton, Dennis R.

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Minimally Mutated HIV-1 Broadly Neutralizing Antibodies to Guide Reductionist Vaccine Design von Jardine, Joseph G, Sok, Devin, Julien, Jean-Philippe, Briney, Bryan, Sarkar, Anita, Liang, Chi-Hui, Scherer, Erin A, Henry Dunand, Carole J, Adachi, Yumiko, Diwanji, Devan, Hsueh, Jessica, Jones, Meaghan, Kalyuzhniy, Oleksandr, Kubitz, Michael, Spencer, Skye, Pauthner, Matthias, Saye-Francisco, Karen L, Sesterhenn, Fabian, Wilson, Patrick C, Galloway, Denise M, Stanfield, Robyn L, Wilson, Ian A, Burton, Dennis R, Schief, William R

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C-103 Germline-targeting vaccine design for HIV von Schief, William

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Priming a broadly neutralizing antibody response to HIV-1 using a germline-targeting immunogen von Jardine, Joseph G., Ota, Takayuki, Sok, Devin, Pauthner, Matthias, Kulp, Daniel W., Kalyuzhniy, Oleksandr, Skog, Patrick D., Thinnes, Theresa C., Bhullar, Deepika, Briney, Bryan, Menis, Sergey, Jones, Meaghan, Kubitz, Mike, Spencer, Skye, Adachi, Yumiko, Burton, Dennis R., Schief, William R., Nemazee, David

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Rational HIV Immunogen Design to Target Specific Germline B Cell Receptors von Jardine, Joseph, Julien, Jean-Philippe, Menis, Sergey, Ota, Takayuki, Kalyuzhniy, Oleksandr, McGuire, Andrew, Sok, Devin, Huang, Po-Ssu, MacPherson, Skye, Jones, Meaghan, Nieusma, Travis, Mathison, John, Baker, David, Ward, Andrew B., Burton, Dennis R., Stamatatos, Leonidas, Nemazee, David, Wilson, Ian A., Schief, William R.

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HIV Vaccine Design to Target Germline Precursors of Glycan-Dependent Broadly Neutralizing Antibodies von Steichen, Jon M., Kulp, Daniel W., Tokatlian, Talar, Escolano, Amelia, Dosenovic, Pia, Stanfield, Robyn L., McCoy, Laura E., Ozorowski, Gabriel, Hu, Xiaozhen, Kalyuzhniy, Oleksandr, Briney, Bryan, Schiffner, Torben, Garces, Fernando, Freund, Natalia T., Gitlin, Alexander D., Menis, Sergey, Georgeson, Erik, Kubitz, Michael, Adachi, Yumiko, Jones, Meaghan, Mutafyan, Andrew A., Yun, Dong Soo, Mayer, Christian T., Ward, Andrew B., Burton, Dennis R., Wilson, Ian A., Irvine, Darrell J., Nussenzweig, Michel C., Schief, William R.

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HIV-1 broadly neutralizing antibody precursor B cells revealed by germline-targeting immunogen von Jardine, Joseph G., Kulp, Daniel W., Havenar-Daughton, Colin, Sarkar, Anita, Briney, Bryan, Sok, Devin, Sesterhenn, Fabian, Ereño-Orbea, June, Kalyuzhniy, Oleksandr, Deresa, Isaiah, Hu, Xiaozhen, Spencer, Skye, Jones, Meaghan, Georgeson, Erik, Adachi, Yumiko, Kubitz, Michael, deCamp, Allan C., Julien, Jean-Philippe, Wilson, Ian A., Burton, Dennis R., Crotty, Shane, Schief, William R.

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Precursor Frequency and Affinity Determine B Cell Competitive Fitness in Germinal Centers, Tested with Germline-Targeting HIV Vaccine Immunogens von Abbott, Robert K., Lee, Jeong Hyun, Menis, Sergey, Skog, Patrick, Rossi, Meghan, Ota, Takayuki, Kulp, Daniel W., Bhullar, Deepika, Kalyuzhniy, Oleksandr, Havenar-Daughton, Colin, Schief, William R., Nemazee, David, Crotty, Shane

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Elicitation of Robust Tier 2 Neutralizing Antibody Responses in Nonhuman Primates by HIV Envelope Trimer Immunization Using Optimized Approaches von Pauthner, Matthias, Havenar-Daughton, Colin, Sok, Devin, Nkolola, Joseph P., Bastidas, Raiza, Boopathy, Archana V., Carnathan, Diane G., Chandrashekar, Abishek, Cirelli, Kimberly M., Cottrell, Christopher A., Eroshkin, Alexey M., Guenaga, Javier, Kaushik, Kirti, Kulp, Daniel W., Liu, Jinyan, McCoy, Laura E., Oom, Aaron L., Ozorowski, Gabriel, Post, Kai W., Sharma, Shailendra K., Steichen, Jon M., de Taeye, Steven W., Tokatlian, Talar, Torrents de la Peña, Alba, Butera, Salvatore T., LaBranche, Celia C., Montefiori, David C., Silvestri, Guido, Wilson, Ian A., Irvine, Darrell J., Sanders, Rogier W., Schief, William R., Ward, Andrew B., Wyatt, Richard T., Barouch, Dan H., Crotty, Shane, Burton, Dennis R.

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HIV-1 neutralizing antibodies induced by native-like envelope trimers von Sanders, Rogier W., van Gils, Marit J., Derking, Ronald, Sok, Devin, Ketas, Thomas J., Burger, Judith A., Ozorowski, Gabriel, Cupo, Albert, Simonich, Cassandra, Goo, Leslie, Arendt, Heather, Kim, Helen J., Lee, Jeong Hyun, Pugach, Pavel, Williams, Melissa, Debnath, Gargi, Moldt, Brian, van Breemen, Mariëlle J., Isik, Gözde, Medina-Ramírez, Max, Back, Jaap Willem, Koff, Wayne C., Julien, Jean-Philippe, Rakasz, Eva G., Seaman, Michael S., Guttman, Miklos, Lee, Kelly K., Klasse, Per Johan, LaBranche, Celia, Schief, William R., Wilson, Ian A., Overbaugh, Julie, Burton, Dennis R., Ward, Andrew B., Montefiori, David C., Dean, Hansi, Moore, John P.

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Vaccine-Elicited Tier 2 HIV-1 Neutralizing Antibodies Bind to Quaternary Epitopes Involving Glycan-Deficient Patches Proximal to the CD4 Binding Site von Crooks, Ema T, Tong, Tommy, Chakrabarti, Bimal, Narayan, Kristin, Georgiev, Ivelin S, Menis, Sergey, Huang, Xiaoxing, Kulp, Daniel, Osawa, Keiko, Muranaka, Janelle, Stewart-Jones, Guillaume, Destefano, Joanne, O'Dell, Sijy, LaBranche, Celia, Robinson, James E, Montefiori, David C, McKee, Krisha, Du, Sean X, Doria-Rose, Nicole, Kwong, Peter D, Mascola, John R, Zhu, Ping, Schief, William R, Wyatt, Richard T, Whalen, Robert G, Binley, James M

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Tailored Immunogens Direct Affinity Maturation toward HIV Neutralizing Antibodies von Briney, Bryan, Sok, Devin, Jardine, Joseph G., Kulp, Daniel W., Skog, Patrick, Menis, Sergey, Jacak, Ronald, Kalyuzhniy, Oleksandr, de Val, Natalia, Sesterhenn, Fabian, Le, Khoa M., Ramos, Alejandra, Jones, Meaghan, Saye-Francisco, Karen L., Blane, Tanya R., Spencer, Skye, Georgeson, Erik, Hu, Xiaozhen, Ozorowski, Gabriel, Adachi, Yumiko, Kubitz, Michael, Sarkar, Anita, Wilson, Ian A., Ward, Andrew B., Nemazee, David, Burton, Dennis R., Schief, William R.

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A Computationally Designed Inhibitor of an Epstein-Barr Viral Bcl-2 Protein Induces Apoptosis in Infected Cells von Procko, Erik, Berguig, Geoffrey Y., Shen, Betty W., Song, Yifan, Frayo, Shani, Convertine, Anthony J., Margineantu, Daciana, Booth, Garrett, Correia, Bruno E., Cheng, Yuanhua, Schief, William R., Hockenbery, David M., Press, Oliver W., Stoddard, Barry L., Stayton, Patrick S., Baker, David

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