Brazilian immunology in Caxambu: beyond vaccination, a tribute to the pioneers of basic research in Chagas disease von Scharfstein, Julio

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Mast Cells in Alveolar Septa of COVID-19 Patients: A Pathogenic Pathway That May Link Interstitial Edema to Immunothrombosis von Motta Junior, Jarbas da Silva, Ribeiro dos Santos Miggiolaro, Anna Flavia, Nagashima, Seigo, Vaz de Paula, Caroline Busatta, Baena, Cristina Pellegrino, Scharfstein, Julio, de Noronha, Lucia

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Subverting bradykinin-evoked inflammation by co-opting the contact system: lessons from survival strategies of Trypanosoma cruzi von Scharfstein, Julio

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P2Y14 Receptor as a Target for Neutrophilia Attenuation in Severe COVID-19 Cases: From Hematopoietic Stem Cell Recruitment and Chemotaxis to Thrombo‐inflammation von Lintzmaier Petiz, Lyvia, Glaser, Talita, Scharfstein, Julio, Ratajczak, Mariusz Z., Ulrich, Henning

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Pleiotropic antifibrotic actions of aspirin-triggered resolvin D1 in the lungs von Guilherme, Rafael F, Silva, José Bruno N F, Waclawiack, Ingrid, Fraga-Junior, Vanderlei S, Nogueira, Thaís O, Pecli, Cyntia, Araújo-Silva, Carlla A, Magalhães, Nathalia S, Lemos, Felipe S, Bulant, Carlos A, Blanco, Pablo J, Serra, Rafaela, Svensjö, Erik, Scharfstein, Júlio, Moraes, João A, Canetti, Claudio, Benjamim, Claudia F

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High mobility group box 1, ATP, lipid mediators, and tissue factor are elevated in COVID‐19 patients: HMGB1 as a biomarker of worst prognosis von Vicentino, Amanda Roberta Revoredo, Fraga‐Junior, Vanderlei da Silva, Palazzo, Matheus, Tasmo, Natalia Recardo Amorim, Rodrigues, Danielle A. S., Barroso, Shana Priscila Coutinho, Ferreira, Sâmila Natiane, Neves‐Borges, Anna Cristina, Allonso, Diego, Fantappié, Marcelo Rosado, Scharfstein, Julio, Oliveira, Ana Carolina, Vianna‐Jorge, Rosane, Vale, André Macedo, Coutinho‐Silva, Robson, Savio, Luiz Eduardo Baggio, Canetti, Claudio, Benjamim, Claudia Farias

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Contact System Activation in Plasma from Dengue Patients Might Harness Endothelial Virus Replication through the Signaling of Bradykinin Receptors von Coelho, Sharton V. A., Rust, Naiara M., Vellasco, Lucas, Papa, Michelle P., Pereira, Aline S. G., da Silva Palazzo, Matheus Ferreira, Juliano, Maria Aparecida, Costa, Simone M., Alves, Ada M. B., Cordeiro, Marli T., Marques, Ernesto T. A., Scharfstein, Julio, de Arruda, Luciana B.

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Novel Family of Insect Salivary Inhibitors Blocks Contact Pathway Activation by Binding to Polyphosphate, Heparin, and Dextran Sulfate von Alvarenga, Patricia H, Xu, Xueqing, Oliveira, Fabiano, Chagas, Andrezza C, Nascimento, Clarissa R, Francischetti, Ivo M.B, Juliano, Maria A, Juliano, Luiz, Scharfstein, Julio, Valenzuela, Jesus G, Ribeiro, José M.C, Andersen, John F

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Proteolytic generation of kinins in tissues infected by Trypanosoma cruzi depends on CXC chemokine secretion by macrophages activated via Toll-like 2 receptors von Schmitz, Veronica, Svensjö, Erik, Serra, Rafaela Rangel, Teixeira, Mauro M., Scharfstein, Julio

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Mast Cell Coupling to the Kallikrein-Kinin System Fuels Intracardiac Parasitism and Worsens Heart Pathology in Experimental Chagas Disease von Nascimento, Clarissa R, Andrade, Daniele, Carvalho-Pinto, Carla Eponina, Serra, Rafaela Rangel, Vellasco, Lucas, Brasil, Guilherme, Ramos-Junior, Erivan Schnaider, da Mota, Julia Barbalho, Almeida, Larissa Nogueira, Andrade, Marcus V, Correia Soeiro, Maria de Nazaré, Juliano, Luiz, Alvarenga, Patrícia Hessab, Oliveira, Ana Carolina, Sicuro, Fernando Lencastre, de Carvalho, Antônio C Campos, Svensjö, Erik, Scharfstein, Julio

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Bradykinin B2 Receptors of dendritic cells, acting as sensors of kinins proteolytically released by Trypanosoma cruzi, are critical for the development of protective type-1 respons... von Monteiro, Ana Carolina, Schmitz, Verônica, Morrot, Alexandre, de Arruda, Luciana Barros, Nagajyothi, Fnu, Granato, Alessandra, Pesquero, João B, Müller-Esterl, Werner, Tanowitz, Herbert B, Scharfstein, Julio

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Ecotin-Like ISP of L. major Promastigotes Fine-Tunes Macrophage Phagocytosis by Limiting the Pericellular Release of Bradykinin from Surface-Bound Kininogens: A Survival Strategy B... von Juliano, Luiz, Vellasco, Lucas, Nogueira de Almeida, Larissa, Svensjö, Erik, Scharfstein, Julio

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Sheltered in Stromal Tissue Cells, Trypanosoma cruzi Orchestrates Inflammatory Neovascularization via Activation of the Mast Cell Chymase Pathway von Vellasco, Lucas, Svensjö, Erik, Bulant, Carlos Alberto, Blanco, Pablo Javier, Nogueira, Fábio, Domont, Gilberto, de Almeida, Natália Pinto, Nascimento, Clarissa Rodrigues, Silva-Dos-Santos, Danielle, Carvalho-Pinto, Carla Eponina, Medei, Emiliano Horácio, Almeida, Igor C, Scharfstein, Julio

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A New Cruzipain-Mediated Pathway of Human Cell Invasion by Trypanosoma cruzi Requires Trypomastigote Membranes von APARICIO, Isabela M, SCHARFSTEIN, Julio, LIMA, Ana Paula C. A

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Kinins Released by Erythrocytic Stages of Plasmodium falciparum Enhance Adhesion of Infected Erythrocytes to Endothelial Cells and Increase Blood Brain Barrier Permeability via Act... von Silva, Leandro S, Pinheiro, Alessandro S, Teixeira, Douglas E, Silva-Aguiar, Rodrigo P, Peruchetti, Diogo B, Scharfstein, Julio, Caruso-Neves, Celso, Pinheiro, Ana Acacia S

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Ecotin-Like ISP of L. major Promastigotes Fine-Tunes Macrophage Phagocytosis by Limiting the Pericellular Release of Bradykinin from Surface-Bound Kininogens: A Survival Strategy B... von Svensjö, Erik, Nogueira de Almeida, Larissa, Vellasco, Lucas, Juliano, Luiz, Scharfstein, Julio

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Protease activated receptor signaling is required for African trypanosome traversal of human brain microvascular endothelial cells von Grab, Dennis J, Garcia-Garcia, Jose C, Nikolskaia, Olga V, Kim, Yuri V, Brown, Amanda, Pardo, Carlos A, Zhang, Yongqing, Becker, Kevin G, Wilson, Brenda A, de A Lima, Ana Paula C, Scharfstein, Julio, Dumler, J Stephen

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Maxadilan, the Lutzomyia longipalpis vasodilator, drives plasma leakage via PAC1–CXCR1/2-pathway von Svensjö, Erik, Saraiva, Elvira M., Amendola, Rafael Silveira, Barja-Fidalgo, Christina, Bozza, Marcelo T., Lerner, Ethan A., Teixeira, Mauro M., Scharfstein, Julio

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Back to the future in Chagas disease: from animal models to patient cohort studies, progress in immunopathogenesis research von Scharfstein, Julio, de Assis Silva Gomes, Juliana, Correa-Oliveira, Rodrigo

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Perspectives on the Trypanosoma cruzi-host cell receptor interactions von Villalta, Fernando, Scharfstein, Julio, Ashton, Anthony W, Tyler, Kevin M, Guan, Fangxia, Mukherjee, Shankar, Lima, Maria F, Alvarez, Sandra, Weiss, Louis M, Huang, Huan, Machado, Fabiana S, Tanowitz, Herbert B

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