Multiplex Genome-Edited T-cell Manufacturing Platform for "Off-the-Shelf" Adoptive T-cell Immunotherapies von Poirot, Laurent, Philip, Brian, Schiffer-Mannioui, Cécile, Le Clerre, Diane, Chion-Sotinel, Isabelle, Derniame, Sophie, Potrel, Pierrick, Bas, Cécile, Lemaire, Laetitia, Galetto, Roman, Lebuhotel, Céline, Eyquem, Justin, Cheung, Gordon Weng-Kit, Duclert, Aymeric, Gouble, Agnès, Arnould, Sylvain, Peggs, Karl, Pule, Martin, Scharenberg, Andrew M, Smith, Julianne

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Targeted gene editing restores regulated CD40L function in X-linked hyper-IgM syndrome von Hubbard, Nicholas, Hagin, David, Sommer, Karen, Song, Yumei, Khan, Iram, Clough, Courtnee, Ochs, Hans D., Rawlings, David J., Scharenberg, Andrew M., Torgerson, Troy R.

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Evaluation of TCR Gene Editing Achieved by TALENs, CRISPR/Cas9, and megaTAL Nucleases von Osborn, Mark J, Webber, Beau R, Knipping, Friederike, Lonetree, Cara-lin, Tennis, Nicole, DeFeo, Anthony P, McElroy, Amber N, Starker, Colby G, Lee, Catherine, Merkel, Sarah, Lund, Troy C, Kelly-Spratt, Karen S, Jensen, Michael C, Voytas, Daniel F, von Kalle, Christof, Schmidt, Manfred, Gabriel, Richard, Hippen, Keli L, Miller, Jeffrey S, Scharenberg, Andrew M, Tolar, Jakub, Blazar, Bruce R

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The Poly(ADP-ribose) Polymerase PARP-1 Is Required for Oxidative Stress-induced TRPM2 Activation in Lymphocytes von Buelow, Ben, Song, Yumei, Scharenberg, Andrew M.

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megaTALs: a rare-cleaving nuclease architecture for therapeutic genome engineering von Boissel, Sandrine, Jarjour, Jordan, Astrakhan, Alexander, Adey, Andrew, Gouble, Agnès, Duchateau, Philippe, Shendure, Jay, Stoddard, Barry L, Certo, Michael T, Baker, David, Scharenberg, Andrew M

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Engineering HIV-Resistant, Anti-HIV Chimeric Antigen Receptor T Cells von Hale, Malika, Mesojednik, Taylor, Romano Ibarra, Guillermo S., Sahni, Jaya, Bernard, Alison, Sommer, Karen, Scharenberg, Andrew M., Rawlings, David J., Wagner, Thor A.

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The SLC41 family of MgtE-like magnesium transporters von Sahni, Jaya, Scharenberg, Andrew M.

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In Vivo Outcome of Homology-Directed Repair at the HBB Gene in HSC Using Alternative Donor Template Delivery Methods von Pattabhi, Sowmya, Lotti, Samantha N., Berger, Mason P., Singh, Swati, Lux, Christopher T., Jacoby, Kyle, Lee, Calvin, Negre, Olivier, Scharenberg, Andrew M., Rawlings, David J.

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SLC41A2 encodes a plasma-membrane Mg2+ transporter von Sahni, Jaya, Nelson, Bruce, Scharenberg, Andrew M

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Improved CRISPR genome editing using small highly active and specific engineered RNA-guided nucleases von Schmidt, Moritz J., Gupta, Ashish, Bednarski, Christien, Gehrig-Giannini, Stefanie, Richter, Florian, Pitzler, Christian, Gamalinda, Michael, Galonska, Christina, Takeuchi, Ryo, Wang, Kui, Reiss, Caroline, Dehne, Kerstin, Lukason, Michael J., Noma, Akiko, Park-Windhol, Cindy, Allocca, Mariacarmela, Kantardzhieva, Albena, Sane, Shailendra, Kosakowska, Karolina, Cafferty, Brian, Tebbe, Jan, Spencer, Sarah J., Munzer, Scott, Cheng, Christopher J., Scaria, Abraham, Scharenberg, Andrew M., Cohnen, André, Coco, Wayne M.

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Ethical and regulatory aspects of genome editing von Kohn, Donald B., Porteus, Matthew H., Scharenberg, Andrew M.

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Genome Editing Technologies: Defining a Path to Clinic von Corrigan-Curay, Jacqueline, O'Reilly, Marina, Kohn, Donald B, Cannon, Paula M, Bao, Gang, Bushman, Frederic D, Carroll, Dana, Cathomen, Toni, Joung, J Keith, Roth, David, Sadelain, Michel, Scharenberg, Andrew M, von Kalle, Christof, Zhang, Feng, Jambou, Robert, Rosenthal, Eugene, Hassani, Morad, Singh, Aparna, Porteus, Matthew H

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Calcium signalling and cell-fate choice in B cells von Scharenberg, Andrew M., Humphries, Lisa A., Rawlings, David J.

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A chemically inducible IL-2 receptor signaling complex allows for effective in vitro and in vivo selection of engineered CD4+ T cells von Cook, Peter J., Yang, Su Jung, Uenishi, Gene I., Grimm, Annaiz, West, Samuel E., Wang, Li-Jie, Jacobs, Chester, Repele, Andrea, Drow, Travis, Boukhris, Ahmad, Dahl, Noelle P., Sommer, Karen, Scharenberg, Andrew M., Rawlings, David J.

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Engineered zinc finger nickases induce homology-directed repair with reduced mutagenic effects von Ramirez, Cherie L, Certo, Michael T, Mussolino, Claudio, Goodwin, Mathew J, Cradick, Thomas J, McCaffrey, Anton P, Cathomen, Toni, Scharenberg, Andrew M, Joung, J Keith

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TRPM7 regulates quiescent/proliferative metabolic transitions in lymphocytes von Sahni, Jaya, Tamura, Richard, Sweet, Ian R., Scharenberg, Andrew M.

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Addendum to: Improved CRISPR genome editing using small highly active and specific engineered RNA-guided nucleases von Schmidt, Moritz J., Gupta, Ashish, Bednarski, Christien, Gehrig-Giannini, Stefanie, Richter, Florian, Pitzler, Christian, Gamalinda, Michael, Galonska, Christina, Takeuchi, Ryo, Wang, Kui, Reiss, Caroline, Dehne, Kerstin, Lukason, Michael J., Noma, Akiko, Park-Windhol, Cindy, Allocca, Mariacarmela, Kantardzhieva, Albena, Sane, Shailendra, Kosakowska, Karolina, Cafferty, Brian, Tebbe, Jan, Spencer, Sarah J., Munzer, Scott, Cheng, Christopher J., Scaria, Abraham, Scharenberg, Andrew M., Cohnen, André, Coco, Wayne M.

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TRPM4 is a Ca2+-activated nonselective cation channel mediating cell membrane depolarization von Launay, Pierre, Fleig, Andrea, Perraud, Anne Laure, Scharenberg, Andrew M, Penner, Reinhold, Kinet, Jean Pierre

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Characterization of homing endonuclease binding and cleavage specificities using yeast surface display SELEX (YSD-SELEX) von Jacoby, Kyle, Lambert, Abigail R, Scharenberg, Andrew M

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SLC41A1 Mg2+ transport is regulated via Mg2+-dependent endosomal recycling through its N-terminal cytoplasmic domain von Mandt, Tyler, Song, Yumei, Scharenberg, Andrew M., Sahni, Jaya

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