Atu027, a liposomal small interfering RNA formulation targeting protein kinase N3, inhibits cancer progression von Aleku, Manuela, Schulz, Petra, Keil, Oliver, Santel, Ansgar, Schaeper, Ute, Dieckhoff, Britta, Janke, Oliver, Endruschat, Jens, Durieux, Birgit, Röder, Nadine, Löffler, Kathrin, Lange, Christian, Fechtner, Melanie, Möpert, Kristin, Fisch, Gerald, Dames, Sibylle, Arnold, Wolfgang, Jochims, Karin, Giese, Klaus, Wiedenmann, Bertram, Scholz, Arne, Kaufmann, Jörg

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S286: TARGETING CONDITIONING‐ELICITED NON‐TRANSFERRIN‐BOUND IRON BY TMPRSS6 SILENCING IMPROVES BONE MARROW TRANSPLANT OUTCOME von Antypiuk, Ada, Martinez, Alberto, Schaeper, Ute, Platzbecker, Uwe, Vinchi, Francesca

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miR-150-PTPMT1-cardiolipin signaling in pulmonary arterial hypertension von Russomanno, Giusy, Jo, Kyeong Beom, Abdul-Salam, Vahitha B., Morgan, Claire, Endruschat, Jens, Schaeper, Ute, Osman, Ahmed H., Alzaydi, Mai M., Wilkins, Martin R., Wojciak-Stothard, Beata

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Atu027 Prevents Pulmonary Metastasis in Experimental and Spontaneous Mouse Metastasis Models von SANTEL, Ansgar, ALEKU, Manuela, EISERMANN, Mona, LÖFFLER, Kathrin, FECHTNER, Melanie, FISCH, Gerald, VANK, Christiane, SCHAEPER, Ute, GIESE, Klaus, KAUFMANN, Jörg, RÖDER, Nadine, MÖPERT, Kristin, DURIEUX, Birgit, JANKE, Oliver, KEIL, Oliver, ENDRUSCHAT, Jens, DAMES, Sibylle, LANGE, Christian

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CLIC4/Arf6 Pathway von Abdul-Salam, Vahitha B, Russomanno, Giusy, Chien-Nien, Chen, Mahomed, Abdul S, Yates, Luke A, Wilkins, Martin R, Zhao, Lan, Gierula, Magdalena, Dubois, Oliver, Schaeper, Ute, Endruschat, Jens, Wojciak-Stothard, Beata

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SLN124, a GalNAc‐siRNA Conjugate Targeting TMPRSS6, Efficiently Prevents Iron Overload in Hereditary Haemochromatosis Type 1 von Altamura, Sandro, Schaeper, Ute, Dames, Sibylle, Löffler, Kathrin, Eisermann, Mona, Frauendorf, Christian, Müdder, Katja, Neves, Joana, Muckenthaler, Martina U.

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Distinct requirements for Gab1 in Met and EGF receptor signaling in vivo von Schaeper, Ute, Vogel, Regina, Chmielowiec, Jolanta, Huelsken, Joerg, Rosario, Marta, Birchmeier, Walter

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Coupling of Gab1 to c-Met, Grb2, and Shp2 Mediates Biological Responses von Schaeper, Ute, Gehring, Niels H., Fuchs, Klaus P., Sachs, Martin, Kempkes, Bettina, Birchmeier, Walter

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Repin1 deficiency in liver tissue alleviates NAFLD progression in mice von Abshagen, Kerstin, Mense, Lars, Fischer, Felix, Liebig, Marie, Schaeper, Ute, Navarro, Gemma, Glass, Änne, Frank, Marcus, Klöting, Nora, Vollmar, Brigitte

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Essential Role of Gab1 for Signaling by the c-Met Receptor in Vivo von Sachs, Martin, Brohmann, Henning, Zechner, Dietmar, Müller, Thomas, Hülsken, Jörg, Walther, Ingrid, Schaeper, Ute, Birchmeier, Carmen, Birchmeier, Walter

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The Docking Protein Gab1 Is an Essential Component of an Indirect Mechanism for Fibroblast Growth Factor Stimulation of the Phosphatidylinositol 3-Kinase/Akt Antiapoptotic Pathway von Lamothe, Betty, Yamada, Masashi, Schaeper, Ute, Birchmeier, Walter, Lax, Irit, Schlessinger, Joseph

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Myelodysplastic Syndromes Benefit from Iron-Restricted Bone Marrow Transplant in Preclinical Mouse Model von Antypiuk, Ada, Martinez, Alberto, Schaeper, Ute, Platzbecker, Uwe, Vinchi, Francesca

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Iron Chelation Efficiency in Human Hepatocytes Is Enhanced By Exogenous Hepcidin von Koonyosying, Pimpisid, Garbowski, Maciej, Schaeper, Ute, Martinez, Alberto, Porter, John B.

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Tmprss6 siRNA Treatment in Mice Stops Hepcidin Reduction across Pregnancy von Fielding, Katherine, Ataide, Ricardo, Bennett, Cavan, Pettikiriarachchi, Anne, Clucas, Danielle, Schaeper, Ute, Pasricha, Sant-Rayn

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Interaction between a Cellular Protein That Binds to the C-terminal Region of Adenovirus E1A (CtBP) and a Novel Cellular Protein Is Disrupted by E1A through a Conserved PLDLS Motif von Schaeper, Ute, Subramanian, T., Lim, Louis, Boyd, Janice M., Chinnadurai, G.

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Signaling of Hepatocyte Growth Factor/Scatter Factor (HGF) to the Small GTPase Rap1 via the Large Docking Protein Gab1 and the Adapter Protein CRKL von Sakkab, Dima, Lewitzky, Marc, Posern, Guido, Schaeper, Ute, Sachs, Martin, Birchmeier, Walter, Feller, Stephan M.

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Liver-specific Bid silencing inhibits APAP-induced cell death in mice von Maxa, Mareike, Schaeper, Ute, Dames, Sibylle, Vollmar, Brigitte, Kuhla, Angela

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Endothelial Tpl2 regulates vascular barrier function via JNK-mediated degradation of claudin-5 promoting neuroinflammation or tumor metastasis von Nanou, Aikaterini, Bourbouli, Mara, Vetrano, Stefania, Schaeper, Ute, Ley, Steven, Kollias, George

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Tmprss6 Depletion-Mediated Iron Deficiency Attenuates the Clinical Course of Plasmodium Berghei Infection in Mice von Clucas, Danielle, Bennett, Cavan, Steel, Ryan, Mellin, Ronan, Caiazzo, Sabrina, Schaeper, Ute, Boddey, Justin, Ataide, Ricardo, Pasricha, Sant-Rayn

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SLN124, a GalNac‐siRNA targeting transmembrane serine protease 6, in combination with deferiprone therapy reduces ineffective erythropoiesis and hepatic iron‐overload in a mouse mo... von Vadolas, Jim, Ng, Garrett Z., Kysenius, Kai, Crouch, Peter J., Dames, Sibylle, Eisermann, Mona, Nualkaew, Tiwaporn, Vilcassim, Shahla, Schaeper, Ute, Grigoriadis, George

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