Biochemical reconstitution of TET1–TDG–BER-dependent active DNA demethylation reveals a highly coordinated mechanism von Weber, Alain R., Krawczyk, Claudia, Robertson, Adam B., Kuśnierczyk, Anna, Vågbø, Cathrine B., Schuermann, David, Klungland, Arne, Schär, Primo

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Embryonic lethal phenotype reveals a function of TDG in maintaining epigenetic stability von Cortázar, Daniel, Kunz, Christophe, Selfridge, Jim, Lettieri, Teresa, Saito, Yusuke, MacDougall, Eilidh, Wirz, Annika, Schuermann, David, Jacobs, Angelika L., Siegrist, Fredy, Steinacher, Roland, Jiricny, Josef, Bird, Adrian, Schär, Primo

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SUMOylation coordinates BERosome assembly in active DNA demethylation during cell differentiation von Steinacher, Roland, Barekati, Zeinab, Botev, Petar, Kuśnierczyk, Anna, Slupphaug, Geir, Schär, Primo

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Tet oxidizes thymine to 5-hydroxymethyluracil in mouse embryonic stem cell DNA von Pfaffeneder, Toni, Spada, Fabio, Wagner, Mirko, Brandmayr, Caterina, Laube, Silvia K, Eisen, David, Truss, Matthias, Steinbacher, Jessica, Hackner, Benjamin, Kotljarova, Olga, Schuermann, David, Michalakis, Stylianos, Kosmatchev, Olesea, Schiesser, Stefan, Steigenberger, Barbara, Raddaoui, Nada, Kashiwazaki, Gengo, Müller, Udo, Spruijt, Cornelia G, Vermeulen, Michiel, Leonhardt, Heinrich, Schär, Primo, Müller, Markus, Carell, Thomas

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Covalent PARylation of DNA base excision repair proteins regulates DNA demethylation von Schwarz, Simon D., Xu, Jianming, Gunasekera, Kapila, Schürmann, David, Vågbø, Cathrine B., Ferrari, Elena, Slupphaug, Geir, Hottiger, Michael O., Schär, Primo, Steinacher, Roland

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Tumor Initiation Capacity and Therapy Resistance Are Differential Features of EMT-Related Subpopulations in the NSCLC Cell Line A549 von Tièche, Colin Charles, Gao, Yanyun, Bührer, Elias Daniel, Hobi, Nina, Berezowska, Sabina Anna, Wyler, Kurt, Froment, Laurène, Weis, Stefan, Peng, Ren-Wang, Bruggmann, Rémy, Schär, Primo, Amrein, Michael Alex, Hall, Sean Ralph Robert, Dorn, Patrick, Kocher, Gregor, Riether, Carsten, Ochsenbein, Adrian, Schmid, Ralph Alexander, Marti, Thomas Michael

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Modulation of Age- and Cancer-Associated DNA Methylation Change in the Healthy Colon by Aspirin and Lifestyle von NOREEN, Faiza, RÖÖSLI, Martin, GAJ, Pawel, PIETRZAK, Jakub, WEIS, Stefan, URFER, Patric, REGULA, Jaroslaw, SCHÄR, Primo, TRUNINGER, Kaspar

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Base excision by thymine DNA glycosylase mediates DNA-directed cytotoxicity of 5-fluorouracil von Kunz, Christophe, Focke, Frauke, Saito, Yusuke, Schuermann, David, Lettieri, Teresa, Selfridge, Jim, Schär, Primo

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Modification of the human thymine-DNA glycosylase by ubiquitin-like proteins facilitates enzymatic turnover von Hardeland, Ulrike, Steinacher, Roland, Jiricny, Josef, Schär, Primo

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Functionality of Human Thymine DNA Glycosylase Requires SUMO-Regulated Changes in Protein Conformation von Steinacher, Roland, Schär, Primo

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Sperm chromatin accessibility’s involvement in the intergenerational effects of stress hormone receptor activation von Fischer, Vincent, Kretschmer, Miriam, Germain, Pierre-Luc, Kaur, Jasmine, Mompart-Barrenechea, Sergio, Pelczar, Pawel, Schürmann, David, Schär, Primo, Gapp, Katharina

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Hierarchical contribution of individual lifestyle factors and their interactions on adenomatous and serrated polyp risk von Kim, Jihee, Nath, Kirti, Schmidlin, Kurt, Schaufelberger, Helen, Quattropani, Christiana, Vannini, Simone, Mossi, Sandro, Thumshirn, Miriam, Manz, Michael, Litichevskiy, Lev, Fan, Jiaxin, Dmitrieva-Posocco, Oxana, Li, Mingyao, Levy, Maayan, Schär, Primo, Zwahlen, Marcel, Thaiss, Christoph A., Truninger, Kaspar

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ELF-MF exposure affects the robustness of epigenetic programming during granulopoiesis von Manser, Melissa, Sater, Mohamad R. Abdul, Schmid, Christoph D., Noreen, Faiza, Murbach, Manuel, Kuster, Niels, Schuermann, David, Schär, Primo

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Versatile recombinant SUMOylation system for the production of SUMO-modified protein von Weber, Alain R, Schuermann, David, Schär, Primo

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Differences in autophagy marker levels at birth in preterm vs. term infants von Künstle, Noëmi, Gorlanova, Olga, Marten, Andrea, Müller, Loretta, Sharma, Pawan, Röösli, Martin, Sinues, Pablo, Schär, Primo, Schürmann, David, Rüttimann, Céline, Da Silva Sena, Carla Rebeca, Nahum, Uri, Usemann, Jakob, Steinberg, Ruth, Yammine, Sophie, Schulzke, Sven, Latzin, Philipp, Frey, Urs

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Sumoylation of poly(ADP-ribose) polymerase 1 inhibits its acetylation and restrains transcriptional coactivator function von Messner, Simon, Schuermann, David, Altmeyer, Matthias, Kassner, Ingrid, Schmidt, Darja, Schär, Primo, Müller, Stefan, Hottiger, Michael O

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Aberrant regulation of epigenetic modifiers contributes to the pathogenesis in patients with selenoprotein N‐related myopathies von Bachmann, Christoph, Noreen, Faiza, Voermans, Nicol C., Schär, Primo L., Vissing, John, Fock, Johanna M., Bulk, Saskia, Kusters, Benno, Moore, Steven A., Beggs, Alan H., Mathews, Katherine D., Meyer, Megan, Genetti, Casie A., Meola, Giovanni, Cardani, Rosanna, Mathews, Emma, Jungbluth, Heinz, Muntoni, Francesco, Zorzato, Francesco, Treves, Susan

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DNA methylation instability by BRAF-mediated TET silencing and lifestyle-exposure divides colon cancer pathways von Noreen, Faiza, Küng, Taya, Tornillo, Luigi, Parker, Hannah, Silva, Miguel, Weis, Stefan, Marra, Giancarlo, Rad, Roland, Truninger, Kaspar, Schär, Primo

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Cell cycle regulation as a mechanism for functional separation of the apparently redundant uracil DNA glycosylases TDG and UNG2 von Hardeland, Ulrike, Kunz, Christophe, Focke, Frauke, Szadkowski, Marta, Schär, Primo

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The versatile thymine DNA‐glycosylase: a comparative characterization of the human, Drosophila and fission yeast orthologs von Hardeland, Ulrike, Bentele, Marc, Jiricny, Josef, Schär, Primo

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