Discovery of the Once-Weekly Glucagon-Like Peptide‑1 (GLP-1) Analogue Semaglutide von Lau, Jesper, Bloch, Paw, Schäffer, Lauge, Pettersson, Ingrid, Spetzler, Jane, Kofoed, Jacob, Madsen, Kjeld, Knudsen, Lotte Bjerre, McGuire, James, Steensgaard, Dorte Bjerre, Strauss, Holger Martin, Gram, Dorte X, Knudsen, Sanne Møller, Nielsen, Flemming Seier, Thygesen, Peter, Reedtz-Runge, Steffen, Kruse, Thomas

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Development of Cagrilintide, a Long-Acting Amylin Analogue von Kruse, Thomas, Hansen, Jakob Lerche, Dahl, Kirsten, Schäffer, Lauge, Sensfuss, Ulrich, Poulsen, Christian, Schlein, Morten, Hansen, Ann Maria Kruse, Jeppesen, Claus Bekker, Dornonville de la Cour, Charlotta, Clausen, Trine Ryberg, Johansson, Eva, Fulle, Simone, Skyggebjerg, Rikke Bjerring, Raun, Kirsten

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Real-time trafficking and signaling of the glucagon-like peptide-1 receptor von Roed, Sarah Noerklit, Wismann, Pernille, Underwood, Christina Rye, Kulahin, Nikolaj, Iversen, Helle, Cappelen, Karen Arevad, Schäffer, Lauge, Lehtonen, Janne, Hecksher-Soerensen, Jacob, Secher, Anna, Mathiesen, Jesper Mosolff, Bräuner-Osborne, Hans, Whistler, Jennifer L., Knudsen, Sanne Moeller, Waldhoer, Maria

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Type II Turn of Receptor-bound Salmon Calcitonin Revealed by X-ray Crystallography von Johansson, Eva, Hansen, Jakob Lerche, Hansen, Ann Maria Kruse, Shaw, Allan Christian, Becker, Peter, Schäffer, Lauge, Reedtz-Runge, Steffen

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A novel high-affinity peptide antagonist to the insulin receptor von Schäffer, Lauge, Brand, Christian L., Hansen, Bo F., Ribel, Ulla, Shaw, Allan C., Slaaby, Rita, Sturis, Jeppe

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Agonism and antagonism at the insulin receptor von Knudsen, Louise, Hansen, Bo Falck, Jensen, Pia, Pedersen, Thomas Åskov, Vestergaard, Kirsten, Schäffer, Lauge, Blagoev, Blagoy, Oleksiewicz, Martin B, Kiselyov, Vladislav V, De Meyts, Pierre

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The arcuate nucleus mediates GLP-1 receptor agonist liraglutide-dependent weight loss von Secher, Anna, Jelsing, Jacob, Baquero, Arian F, Hecksher-Sørensen, Jacob, Cowley, Michael A, Dalbøge, Louise S, Hansen, Gitte, Grove, Kevin L, Pyke, Charles, Raun, Kirsten, Schäffer, Lauge, Tang-Christensen, Mads, Verma, Saurabh, Witgen, Brent M, Vrang, Niels, Bjerre Knudsen, Lotte

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Activation of the Insulin Receptor by Insulin and a Synthetic Peptide Leads to Divergent Metabolic and Mitogenic Signaling and Responses von Jensen, Maja, Hansen, Bente, De Meyts, Pierre, Schäffer, Lauge, Ursø, Birgitte

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Albumin Binding of Acylated Insulin (NN304) Does Not Deter Action to Stimulate Glucose Uptake von Dea, Melvin K, Hamilton-Wessler, Marianthe, Ader, Marilyn, Moore, Donna, Schäffer, Lauge, Loftager, Mette, Vølund, Aage, Bergman, Richard N

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A model for insulin binding to the insulin receptor von SCHÄFFER, Lauge

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Assembly of High-Affinity Insulin Receptor Agonists and Antagonists from Peptide Building Blocks von Schäffer, Lauge, Brissette, Renee E., Spetzler, Jane C., Pillutla, Renuka C., Østergaard, Søren, Lennick, Michael, Brandt, Jakob, Fletcher, Paul W., Danielsen, Gillian M., Hsiao, Ku-Chuan, Andersen, Asser S., Dedova, Olga, Ribel, Ulla, Hoeg-Jensen, Thomas, Hansen, Per Hertz, Blume, Arthur J., Markussen, Jan, Goldstein, Neil I.

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Hybrid Receptors Formed by Insulin Receptor (IR) and Insulin-like Growth Factor I Receptor (IGF-IR) Have Low Insulin and High IGF-1 Affinity Irrespective of the IR Splice Variant von Slaaby, Rita, Schäffer, Lauge, Lautrup-Larsen, Inger, Andersen, Asser Sloth, Shaw, Allan Christian, Mathiasen, Ida Stenfeldt, Brandt, Jakob

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Correlations of receptor binding and metabolic and mitogenic potencies of insulin analogs designed for clinical use von KURTZHALS, P, SCHÄFFER, L, SØRENSEN, A, KRISTENSEN, C, JONASSEN, I, SCHMID, C, TRÜB, T

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Activation of the insulin receptor (IR) by insulin and a synthetic peptide has different effects on gene expression in IR-transfected L6 myoblasts von Jensen, Maja, Palsgaard, Jane, Borup, Rehannah, de Meyts, Pierre, Schäffer, Lauge

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Beta cell specific probing with fluorescent exendin-4 is progressively reduced in type 2 diabetic mouse models von Lehtonen, Janne, Schäffer, Lauge, Rasch, Morten Grønbech, Hecksher-Sørensen, Jacob, Ahnfelt-Rønne, Jonas

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Crystal structure of the calcitonin receptor ectodomain in complex with a truncated salmon calcitonin analogue von Johansson, Eva, Hansen, Jakob L., Hansen, Ann Maria K., Shaw, Allan C., Becker, Peter, Schäffer, Lauge, Reedtz-Runge, Steffen

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Total Synthesis of desB30 Insulin Analogues by Biomimetic Folding of Single-Chain Precursors von Tofteng, A. Pernille, Jensen, Knud J., Schäffer, Lauge, Hoeg-Jensen, Thomas

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Salmon calcitonin distributes into the arcuate nucleus to a subset of NPY neurons in mice von Zakariassen, Hannah Louise, John, Linu Mary, Lykkesfeldt, Jens, Raun, Kirsten, Glendorf, Tine, Schaffer, Lauge, Lundh, Sofia, Secher, Anna, Lutz, Thomas Alexander, Le Foll, Christelle

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Insulins with built-in glucose sensors for glucose responsive insulin release von Hoeg-Jensen, Thomas, Ridderberg, Signe, Havelund, Svend, Schäffer, Lauge, Balschmidt, Per, Jonassen, Ib, Vedsø, Per, Olesen, Preben H., Markussen, Jan

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Salmon calcitonin distributes into the arcuate nucleus in mice to a subset of NPY neurons von Zakariassen, Hannah Louise, John, Linu Mary, Lykkesfeldt, Jens, Raun, Kirsten, Glendorf, Tine, Schaffer, Lauge, Lundh, Sofia, Secher, Anna, Lutz, Thomas A, Le Foll, Christelle

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