PAX3-FOXO1: Zooming in on an “undruggable” target von Wachtel, Marco, Schäfer, Beat W.

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Duxbling Stem Cells Meet Tumorigenesis von Schäfer, Beat W.

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BAF complexes drive proliferation and block myogenic differentiation in fusion-positive rhabdomyosarcoma von Laubscher, Dominik, Gryder, Berkley E., Sunkel, Benjamin D., Andresson, Thorkell, Wachtel, Marco, Das, Sudipto, Roschitzki, Bernd, Wolski, Witold, Wu, Xiaoli S., Chou, Hsien-Chao, Song, Young K., Wang, Chaoyu, Wei, Jun S., Wang, Meng, Wen, Xinyu, Ngo, Quy Ai, Marques, Joana G., Vakoc, Christopher R., Schäfer, Beat W., Stanton, Benjamin Z., Khan, Javed

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The Proprotein Convertase Furin Contributes to Rhabdomyosarcoma Malignancy by Promoting Vascularization, Migration and Invasion von Jaaks, Patricia, D'Alessandro, Valentina, Grob, Nicole, Büel, Sina, Hajdin, Katarina, Schäfer, Beat W, Bernasconi, Michele

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Phenotypic profiling with a living biobank of primary rhabdomyosarcoma unravels disease heterogeneity and AKT sensitivity von Manzella, Gabriele, Schreck, Leonie D., Breunis, Willemijn B., Molenaar, Jan, Merks, Hans, Barr, Frederic G., Sun, Wenyue, Römmele, Michaela, Zhang, Luduo, Tchinda, Joelle, Ngo, Quy A., Bode, Peter, Delattre, Olivier, Surdez, Didier, Rekhi, Bharat, Niggli, Felix K., Schäfer, Beat W., Wachtel, Marco

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Single cell transcriptomic profiling identifies tumor-acquired and therapy-resistant cell states in pediatric rhabdomyosarcoma von Danielli, Sara G., Wei, Yun, Dyer, Michael A., Stewart, Elizabeth, Sheppard, Heather, Wachtel, Marco, Schäfer, Beat W., Patel, Anand G., Langenau, David M.

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A combinatorial drug screen in PDX-derived primary rhabdomyosarcoma cells identifies the NOXA - BCL-XL/MCL-1 balance as target for re-sensitization to first-line therapy in recurre... von Manzella, Gabriele, Moonamale, Devmini C., Römmele, Michaela, Bode, Peter, Wachtel, Marco, Schäfer, Beat W.

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USP19 deubiquitinates EWS-FLI1 to regulate Ewing sarcoma growth von Gierisch, Maria E., Pedot, Gloria, Walser, Franziska, Lopez-Garcia, Laura A., Jaaks, Patricia, Niggli, Felix K., Schäfer, Beat W.

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Fenretinide induces a new form of dynamin-dependent cell death in pediatric sarcoma von Brack, Eva, Wachtel, Marco, Wolf, Anja, Kaech, Andres, Ziegler, Urs, Schäfer, Beat W.

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Targets for cancer therapy in childhood sarcomas von Wachtel, Marco, Schäfer, Beat W

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Proteasomal Degradation of the EWS-FLI1 Fusion Protein Is Regulated by a Single Lysine Residue von Gierisch, Maria E., Pfistner, Franziska, Lopez-Garcia, Laura A., Harder, Lena, Schäfer, Beat W., Niggli, Felix K.

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PAX3-FOXO1 uses its activation domain to recruit CBP/P300 and shape RNA Pol2 cluster distribution von Asante, Yaw, Benischke, Katharina, Osman, Issra, Ngo, Quy A., Wurth, Jakob, Laubscher, Dominik, Kim, Hyunmin, Udhayakumar, Bhavatharini, Khan, Md Imdadul H., Chin, Diana H., Porch, Jadon, Chakraborty, Maharshi, Sallari, Richard, Delattre, Olivier, Zaidi, Sakina, Morice, Sarah, Surdez, Didier, Danielli, Sara G., Schäfer, Beat W., Gryder, Berkley E., Wachtel, Marco

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Inhibition of HDACs reduces Ewing sarcoma tumor growth through EWS-FLI1 protein destabilization von Pedot, Gloria, Marques, Joana Graça, Ambühl, Philip P, Wachtel, Marco, Kasper, Stephanie, Ngo, Quy A, Niggli, Felix K, Schäfer, Beat W

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CRISPR activation screen identifies TGFβ-associated PEG10 as a crucial tumor suppressor in Ewing sarcoma von Saratov, Vadim, Ngo, Quy A., Pedot, Gloria, Sidorov, Semjon, Wachtel, Marco, Niggli, Felix K., Schäfer, Beat W.

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Corrigendum to "Inhibition of HDACs reduces Ewing sarcoma tumor growth through EWS-FLI1 protein destabilization" [Neoplasia volume 27 (2022) pp. 100784/Number C] von Pedot, Gloria, Marques, Joana Graça, Ambühl, Philip P, Wachtel, Marco, Kasper, Stephanie, Ngo, Quy A, Niggli, Felix K, Schäfer, Beat W

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Author Correction: CRISPR activation screen identifies TGFβ-associated PEG10 as a crucial tumor suppressor in Ewing sarcoma von Saratov, Vadim, Ngo, Quy A., Pedot, Gloria, Sidorov, Semjon, Wachtel, Marco, Niggli, Felix K., Schäfer, Beat W.

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Fenretinide Acts as Potent Radiosensitizer for Treatment of Rhabdomyosarcoma Cells von Brack, Eva, Bender, Sabine, Wachtel, Marco, Pruschy, Martin, Schäfer, Beat W.

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YAP/TAZ inhibition reduces metastatic potential of Ewing sarcoma cells von Bierbaumer, Lisa, Katschnig, Anna M., Radic-Sarikas, Branka, Kauer, Maximilian O., Petro, Jeffrey A., Högler, Sandra, Gurnhofer, Elisabeth, Pedot, Gloria, Schäfer, Beat W., Schwentner, Raphaela, Mühlbacher, Karin, Kromp, Florian, Aryee, Dave N. T., Kenner, Lukas, Uren, Aykut, Kovar, Heinrich

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Small-molecule screen identifies modulators of EWS/FLI1 target gene expression and cell survival in Ewing's sarcoma von Boro, Aleksandar, Prêtre, Kathya, Rechfeld, Florian, Thalhammer, Verena, Oesch, Susanne, Wachtel, Marco, Schäfer, Beat W., Niggli, Felix K.

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Targeting the EWS-ETS transcriptional program by BET bromodomain inhibition in Ewing sarcoma von Hensel, Tim, Giorgi, Chiara, Schmidt, Oxana, Calzada-Wack, Julia, Neff, Frauke, Buch, Thorsten, Niggli, Felix K, Schäfer, Beat W, Burdach, Stefan, Richter, Günther H S

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