Targeting the extrinsic apoptosis signaling pathway for cancer therapy von Sayers, Thomas J.

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Increased secretory leukocyte protease inhibitor (SLPI) production by highly metastatic mouse breast cancer cells von Sayers, Kevin T, Brooks, Alan D, Sayers, Thomas J, Chertov, Oleg

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Sensitization of Tumor Cells to NK Cell-Mediated Killing by Proteasome Inhibition von Hallett, William H.D, Ames, Erik, Motarjemi, Milad, Barao, Isabel, Shanker, Anil, Tamang, David L, Sayers, Thomas J, Hudig, Dorothy, Murphy, William J

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Bortezomib sensitizes human renal cell carcinomas to TRAIL apoptosis through increased activation of caspase-8 in the death-inducing signaling complex von Brooks, Alan D, Jacobsen, Kristen M, Li, Wenqing, Shanker, Anil, Sayers, Thomas J

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Inhibition of Acute Graft-versus-Host Disease with Retention of Graft-versus-Tumor Effects by the Proteasome Inhibitor Bortezomib von Sun, Kai, Welniak, Lisbeth A., Panoskaltsis-Mortari, Angela, O'Shaughnessy, Matthew J., Liu, Haiyan, Barao, Isabel, Riordan, William, Sitcheran, Raquel, Wysocki, Christian, Serody, Jonathan S., Blazar, Bruce R., Sayers, Thomas J., Murphy, William J., Vitetta, Ellen S.

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Impact of dietary components on NK and Treg cell function for cancer prevention von Kim, Young S., Sayers, Thomas J., Colburn, Nancy H., Milner, John A., Young, Howard A.

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The proteasome inhibitor PS-341 sensitizes neoplastic cells to TRAIL-mediated apoptosis by reducing levels of c-FLIP von Sayers, Thomas J., Brooks, Alan D., Koh, Crystal Y., Ma, Weihong, Seki, Naoko, Raziuddin, Arati, Blazar, Bruce R., Zhang, Xia, Elliott, Peter J., Murphy, William J.

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NKG2D recognition and perforin effector function mediate effective cytokine immunotherapy of cancer von Smyth, Mark J, Swann, Jeremy, Kelly, Janice M, Cretney, Erika, Yokoyama, Wayne M, Diefenbach, Andreas, Sayers, Thomas J, Hayakawa, Yoshihiro

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NK Cells Preferentially Target Tumor Cells with a Cancer Stem Cell Phenotype von Ames, Erik, Canter, Robert J, Grossenbacher, Steven K, Mac, Stephanie, Chen, Mingyi, Smith, Rachel C, Hagino, Takeshi, Perez-Cunningham, Jessica, Sckisel, Gail D, Urayama, Shiro, Monjazeb, Arta M, Fragoso, Ruben C, Sayers, Thomas J, Murphy, William J

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Differential effects of proteasome inhibition by bortezomib on murine acute graft-versus-host disease (GVHD): delayed administration of bortezomib results in increased GVHD-depende... von Sun, Kai, Wilkins, Danice E.C., Anver, Miriam R., Sayers, Thomas J., Panoskaltsis-Mortari, Angela, Blazar, Bruce R., Welniak, Lisbeth A., Murphy, William J.

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Bortezomib sensitizes human esophageal squamous cell carcinoma cells to TRAIL-mediated apoptosis via activation of both extrinsic and intrinsic apoptosis pathways von Seki, Naoko, Toh, Uhi, Sayers, Thomas J, Fujii, Teruhiko, Miyagi, Motoshi, Akagi, Yoshito, Kusukawa, Jingo, Kage, Masayoshi, Shirouzu, Kazuo, Yamana, Hideaki

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TNF-related apoptosis-inducing ligand as a therapeutic agent in autoimmunity and cancer von Cretney, Erika, Shanker, Anil, Yagita, Hideo, Smyth, Mark J, Sayers, Thomas J

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cell-based high-throughput screen to identify synergistic TRAIL sensitizers von Booth, Nancy Lynn, Sayers, Thomas J, Brooks, Alan D, Thomas, Cheryl L, Jacobsen, Kristen, Goncharova, Ekaterina I, McMahon, James B, Henrich, Curtis J

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Unlocking the secrets of cytotoxic granule proteins von Smyth, Mark J., Kelly, Janice M., Sutton, Vivien R., Davis, Joanne E., Browne, Kylie A., Sayers, Thomas J., Trapani, Joseph A.

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ELISPOT Assay for Monitoring Cytotoxic T Lymphocytes (CTL) Activity in Cancer Vaccine Clinical Trials von Malyguine, Anatoli M, Strobl, Susan, Dunham, Kimberly, Shurin, Michael R, Sayers, Thomas J

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Optimized combination therapy using bortezomib, TRAIL and TLR agonists in established breast tumors von Lee, Sujin, Yagita, Hideo, Sayers, Thomas J, Celis, Esteban

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Small-Molecule Natural Product Physachenolide C Potentiates Immunotherapy Efficacy by Targeting BET Proteins von Tewary, Poonam, Brooks, Alan D., Xu, Ya-Ming, Wijeratne, E. M. Kithsiri, Babyak, Ashley L., Back, Timothy C., Chari, Raj, Evans, Christine N., Henrich, Curtis J., Meyer, Thomas J., Edmondson, Elijah F., de Aquino, Maria T. Prudente, Kanagasabai, Thanigaivelan, Shanker, Anil, Gunatilaka, A. A. Leslie, Sayers, Thomas J.

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Tumor-Specific CTL Kill Murine Renal Cancer Cells Using Both Perforin and Fas Ligand-Mediated Lysis In Vitro, But Cause Tumor Regression In Vivo in the Absence of Perforin von Seki, Naoko, Brooks, Alan D, Carter, Clive R. D, Back, Timothy C, Parsoneault, Erin M, Smyth, Mark J, Wiltrout, Robert H, Sayers, Thomas J

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Sensitization of renal carcinoma cells to TRAIL-induced apoptosis by rocaglamide and analogs von Nalli, Ancy D., Brown, Lauren E., Thomas, Cheryl L., Sayers, Thomas J., Porco, John A., Henrich, Curtis J.

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Discordant Regulation of Granzyme H and Granzyme B Expression in Human Lymphocytes von Sedelies, Karin A., Sayers, Thomas J., Edwards, Kirsten M., Chen, Weisan, Pellicci, Daniel G., Godfrey, Dale I., Trapani, Joseph A.

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