Vosaroxin plus cytarabine versus placebo plus cytarabine in patients with first relapsed or refractory acute myeloid leukaemia (VALOR): a randomised, controlled, double-blind, mult... von Ravandi, Farhad, Prof, Ritchie, Ellen K, MD, Sayar, Hamid, MD, Lancet, Jeffrey E, MD, Craig, Michael D, MD, Vey, Norbert, Prof, Strickland, Stephen A, MD, Schiller, Gary J, Prof, Jabbour, Elias, MD, Erba, Harry P, Prof, Pigneux, Arnaud, Prof, Horst, Heinz-August, Prof, Recher, Christian, Prof, Klimek, Virginia M, MD, Cortes, Jorge, Prof, Roboz, Gail J, MD, Odenike, Olatoyosi, MD, Thomas, Xavier, MD, Havelange, Violaine, MD, Maertens, Johan, Prof, Derigs, Hans-Günter, Prof, Heuser, Michael, MD, Damon, Lloyd, Prof, Powell, Bayard L, Prof, Gaidano, Gianluca, Prof, Carella, Angelo-Michele, MD, Wei, Andrew, MBBS, Hogge, Donna, Prof, Craig, Adam R, MD, Fox, Judith A, PhD, Ward, Renee, MD, Smith, Jennifer A, PhD, Acton, Gary, MD, Mehta, Cyrus, Prof, Stuart, Robert K, MD, Kantarjian, Hagop M, Prof

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Management of adverse events in patients with acute myeloid leukemia in remission receiving oral azacitidine: experience from the phase 3 randomized QUAZAR AML-001 trial von Ravandi, Farhad, Roboz, Gail J., Wei, Andrew H., Döhner, Hartmut, Pocock, Christopher, Selleslag, Dominik, Montesinos, Pau, Sayar, Hamid, Musso, Maurizio, Figuera-Alvarez, Angela, Safah, Hana, Tse, William, Sohn, Sang Kyun, Hiwase, Devendra, Chevassut, Timothy, Pierdomenico, Francesca, La Torre, Ignazia, Skikne, Barry, Bailey, Rochelle, Zhong, Jianhua, Beach, C. L., Dombret, Herve

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Primary Myeloid Sarcoma of the Prostate: A Case Report and Literature Review von Nguyen, Ryan, Sayar, Hamid

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Where West Meets East: The Complex mtDNA Landscape of the Southwest and Central Asian Corridor von Quintana-Murci, Lluís, Chaix, Raphaëlle, Wells, R. Spencer, Behar, Doron M., Sayar, Hamid, Scozzari, Rosaria, Rengo, Chiara, Al-Zahery, Nadia, Semino, Ornella, Santachiara-Benerecetti, A. Silvana, Coppa, Alfredo, Ayub, Qasim, Mohyuddin, Aisha, Tyler-Smith, Chris, Qasim Mehdi, S., Torroni, Antonio, McElreavey, Ken

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Phase 3 results for vosaroxin/cytarabine in the subset of patients ≥60 years old with refractory/early relapsed acute myeloid leukemia von Ravandi, Farhad, Ritchie, Ellen K, Sayar, Hamid, Lancet, Jeffrey E, Craig, Michael D, Vey, Norbert, Strickland, Stephen A, Schiller, Gary J, Jabbour, Elias, Pigneux, Arnaud, Horst, Heinz-August, Récher, Christian, Klimek, Virginia M, Cortes, Jorge E, Carella, Angelo-Michele, Egyed, Miklos, Krug, Utz, Fox, Judith A, Craig, Adam R, Ward, Renee, Smith, Jennifer A, Acton, Gary, Kantarjian, Hagop M, Stuart, Robert K

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Y-Chromosome Lineages Trace Diffusion of People and Languages in Southwestern Asia von Quintana-Murci, Lluís, Krausz, Csilla, Zerjal, Tatiana, Sayar, S.Hamid, Hammer, Michael F., Mehdi, S.Qasim, Ayub, Qasim, Qamar, Raheel, Mohyuddin, Aisha, Radhakrishna, Uppala, Jobling, Mark A., Tyler-Smith, Chris, McElreavey, Ken

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Role of ethnicity in thrombotic and hemorrhagic complications of myeloproliferative neoplasms von Peseski, Andrew, Saliba, Antoine, Sayar, Hamid

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Acute Promyelocytic Leukemia Presenting with Severe Marrow Fibrosis von Shah, Harsh, Sayar, Hamid, Bradford, Carol

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Therapies for acute myeloid leukemia: vosaroxin von Sayar, Hamid, Bashardoust, Parvaneh

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Oral Azacitidine Maintenance Therapy for Acute Myeloid Leukemia in First Remission von Wei, Andrew H, Döhner, Hartmut, Pocock, Christopher, Montesinos, Pau, Afanasyev, Boris, Dombret, Hervé, Ravandi, Farhad, Sayar, Hamid, Jang, Jun-Ho, Porkka, Kimmo, Selleslag, Dominik, Sandhu, Irwindeep, Turgut, Mehmet, Giai, Valentina, Ofran, Yishai, Kizil Çakar, Merih, Botelho de Sousa, Aida, Rybka, Justyna, Frairia, Chiara, Borin, Lorenza, Beltrami, Germana, Čermák, Jaroslav, Ossenkoppele, Gert J, La Torre, Ignazia, Skikne, Barry, Kumar, Keshava, Dong, Qian, Beach, C.L, Roboz, Gail J

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P62SQSTM1 Affects Interacting Substrates MDM2, MDMX and Casein Kinase 1alpha to Yield Protection of Beta-Catenin Along with p53 Silencing for Refractory AML von Layer, Justin, Rangaraju, Sravanti, Pasupuleti, Santhosh, Cripe, Larry D., Sayar, Hamid, Sargent, Katie J, Weisenbach, Jill, Salman, Huda S., Roodman, G. David, Mayo, Linsey, Kapur, Reuben, Dave', Utpal P, Boswell, H. Scott

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Azacitidine in Lower-Risk Myelodysplastic Syndromes: AMeta-Analysis of Data from Prospective Studies von Komrokji, R, Swern, AS, Grinblatt, D, Lyons, RM, Tobiasson, M, Silverman, LR, Sayar, H, Vij, R, Fliss, A, Tu, N

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Evorpacept (ALX148), a CD47-Blocking Myeloid Checkpoint Inhibitor, in Combination with Azacitidine: A Phase 1 / 2 Study in Patients with Myelodysplastic Syndrome (ASPEN-02) von Garcia-Manero, Guillermo, Erba, Harry P., Sanikommu, Srinivasa R., Altman, Jessica K., Sayar, Hamid, Scott, Bart L., Fong, Abraham P., Guan, Shanhong, Jin, Feng, Forgie, Alison J., Pons, Jaume, Randolph, Sophia S., Byrne, Michael T.

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Long-Term Overall Survival (OS) with Oral Azacitidine (Oral-AZA) in Patients with Acute Myeloid Leukemia (AML) in First Remission after Intensive Chemotherapy (IC): Updated Results... von Wei, Andrew H., Döhner, Hartmut, Sayar, Hamid, Ravandi, Farhad, Montesinos, Pau, Dombret, Hervé, Selleslag, Dominik, Porkka, Kimmo, Jang, Jun Ho, Skikne, Barry, Beach, C.L., Tian, Yu (Olivia), Roboz, Gail J.

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Long‐term outcome of NPM1 mutated acute myeloid leukemia: A single‐institution experience von Sayar, Hamid, Bashardoust, Parvaneh, Cripe, Larry, Chakraborty, Sujata, Bai, Shaochun

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Azacitidine in Lower‐Risk Myelodysplastic Syndromes: A Meta‐Analysis of Data from Prospective Studies von Komrokji, Rami, Swern, Arlene S., Grinblatt, David, Lyons, Roger M., Tobiasson, Magnus, Silverman, Lewis R., Sayar, Hamid, Vij, Ravi, Fliss, Albert, Tu, Nora, Sugrue, Mary M.

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Cooperativity between Flt3/Syk and Proteasome Inhibitors in Flt3mutant/Wildtype AML, By Acting on the Oxphos and Wnt Endpoints of Syk and p62SQSTM1 Pathways Prohibits Protective Au... von Rangaraju, Sravanti, Marino, Silvia, Roodman, G. David, Cripe, Larry D., Ramdas, Baskar, Palam, Lakshmi Reddy, Sargent, Katie J, Sayar, Hamid, Konig, Heiko, Kapur, Reuben, Boswell, H. Scott

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Does race play a role in complications and outcomes of Philadelphia chromosome-negative myeloproliferative neoplasms? von Peseski, Andrew M., Saliba, Antoine N., Althouse, Sandra K., Sayar, Hamid

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Combination of sorafenib, vorinostat and bortezomib for the treatment of poor-risk AML: report of two consecutive clinical trials von Sayar, Hamid, Cripe, Larry D., Saliba, Antoine N., Abu Zaid, Mohammad, Konig, Heiko, Boswell, H. Scott

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Abstract 800: Exploiting the proteasome to overcome RAS and WT1 mutation mediated resistance to FLT-3 inhibition in acute myeloid leukemia von Rangaraju, Sravanti, Pasupuleti, Santosh Kumar, Marino, Silvia, Petrusca, Daniela Nicoleta, Cripe, Larry D., Ramdas, Bhaskar, Palam, Lakshmi Reddy, Sargent, Katie J., Sayar, Hamid, Konig, Heiko, Kapur, Reuben, Roodman, David G., Boswell, Scott H.

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