Small molecule inhibition of Dynamin-dependent endocytosis targets multiple niche signals and impairs leukemia stem cells von Tremblay, Cedric S., Chiu, Sung Kai, Saw, Jesslyn, McCalmont, Hannah, Litalien, Veronique, Boyle, Jacqueline, Sonderegger, Stefan E., Chau, Ngoc, Evans, Kathryn, Cerruti, Loretta, Salmon, Jessica M., McCluskey, Adam, Lock, Richard B., Robinson, Phillip J., Jane, Stephen M., Curtis, David J.

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Author Correction: Small molecule inhibition of Dynamin-dependent endocytosis targets multiple niche signals and impairs leukemia stem cells von Tremblay, Cedric S., Chiu, Sung Kai, Saw, Jesslyn, McCalmont, Hannah, Litalien, Veronique, Boyle, Jacqueline, Sonderegger, Stefan E., Chau, Ngoc, Evans, Kathryn, Cerruti, Loretta, Salmon, Jessica M., McCluskey, Adam, Lock, Richard B., Robinson, Phillip J., Jane, Stephen M., Curtis, David J.

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ZEB2 and LMO2 drive immature T-cell lymphoblastic leukemia via distinct oncogenic mechanisms von Goossens, Steven, Wang, Jueqiong, Tremblay, Cedric S, De Medts, Jelle, T'Sas, Sara, Nguyen, Thao, Saw, Jesslyn, Haigh, Katharina, Curtis, David J, Van Vlierberghe, Pieter, Berx, Geert, Taghon, Tom, Haigh, Jody J

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Restricted cell cycle is essential for clonal evolution and therapeutic resistance of pre-leukemic stem cells von Tremblay, Cedric S., Saw, Jesslyn, Chiu, Sung Kai, Wong, Nicholas C., Tsyganov, Kirill, Ghotb, Sarah, Graham, Alison N., Yan, Feng, Guirguis, Andrew A., Sonderegger, Stefan E., Lee, Nicole, Kalitsis, Paul, Reynolds, John, Ting, Stephen B., Powell, David R., Jane, Stephen M., Curtis, David J.

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Attenuated Acceleration to Leukemia after Ezh2 Loss in Nup98‐HoxD13 (NHD13) Myelodysplastic Syndrome von Ling, Victoria Y., Saw, Jesslyn, Tremblay, Cedric S., Sonderegger, Stefan E., Toulmin, Emma, Boyle, Jacqueline, Chiu, Sung Kai, Lane, Steven W., Ting, Stephen B., Curtis, David J.

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3203 – STAT5 ACTIVATION PROMOTES PROGRESSION AND CHEMOTHERAPY-RESISTANCE IN EARLY T-CELL PRECURSOR ACUTE LYMPHOBLASTIC LEUKEMIA von Tremblay, Cedric, Saw, Jesslyn, Boyle, Jacqueline, Haigh, Katharina, Lock, Richard, Jane, Stephen, Haigh, Jody, Curtis, David

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Non-Linear Trajectories of the Epigenome during T-Cell Leukemogenesis Revealed By Analysis of a Mouse Model of Human ETP-ALL von Yan, Feng, Tremblay, Cedric, Garret-Bakelman, Francine, Saw, Jesslyn, McCormack, Matthew P., Abdollahi, Shokoufeh, Van Vlierberghe, Pieter, Powell, David, Wong, Nicholas C., Curtis, David J.

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Either Scl or Lyl1 Is Required to Maintain Primitive Erythropoiesis von Chiu, Sung Kai, Tremblay, Cedric, Saw, Jesslyn, Curtis, David J.

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STAT5 activation promotes progression and chemotherapy resistance in early T-cell precursor acute lymphoblastic leukemia von Tremblay, Cedric S., Saw, Jesslyn, Boyle, Jacqueline A., Haigh, Katharina, Litalien, Veronique, McCalmont, Hannah, Evans, Kathryn, Lock, Richard B., Jane, Stephen M., Haigh, Jody J., Curtis, David J.

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3173 – AP2A2 KO MICE LINK FETAL LIVER HAEMATOPOIESIS EXHAUSTION TO LOSS OF HSC QUIESCENCE, PERTURBED ASYMMETRICAL FATE AND ALTERED LIPID METABOLISM von Ting, Stephen, Rhost, Sara, Saw, Jesslyn, Curtis, David, Magor, Graham, Perkins, Andrew

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Scl and Lyl1 Are Redundant in Erythropoiesis von Chiu, Sung Kai, Tremblay, Cedric, Saw, Jesslyn, Curtis, David J.

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Inhibition of endocytosis restrains niche-mediated signalling and sensitizes pre-leukemic stem cells to chemotherapy von Tremblay, Cedric, Chiu, Sung, Saw, Jesslyn, Robinson, Philip, Curtis, David

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Cdkn1A (p21) is required for quiescence, therapeutic resistance and clonal evolution of pre-leukemic stem cells von Tremblay, Cedric, Saw, Jesslyn, Curtis, David

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2014 - DYNAMIN-DEPENDENT ENDOCYTOSIS IS REQUIRED FOR MULTIPLE NICHE SIGNALS THAT ARE CRUCIAL FOR LEUKEMIA STEM CELL ACTIVITY AND CHEMORESISTANCE von Tremblay, Cedric, chiu, sung, Saw, Jesslyn, Sonderegger, Stefan, Chau, Ngoc, McCluskey, Adam, Robinson, Phillip, Jane, Stephen, Curtis, David

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3178 – LONGITUDINAL DRUG INCORPORATION, CLONAL COMPOSITION, AND DNA METHYLATION DYNAMICS IN MDS/CMML PATIENTS TREATED WITH AZA von Thoms, Julie, Hampton, Henry, Yan, Feng, Davidson, Sarah, Joshi, Swapna, Sarowar, Chowdhury, Lim, Xin Ying, Nunez, Andrea, Kakadia, Purvi, Saw, Jesslyn, Bhuyan, Golam Sarower, Zou, Xiaoheng, Ghodousi, Elaheh, Jolly, Christopher, Koch, Forrest, Vafaee, Fatemeh, Pickford, Russell, Raftery, Mark, Hough, Sally, Buckland, Griselda, Bailey, Michelle, Ghodke, Yuvaraj, Absar, Noorul, Vaughan, Lachlin, Pasalic, Leonardo, Fong, Chun, Kenealy, Melita, Hiwase, Devendra, Stoddart, Rohanna, Mohammed, Soma, Lee, Linda, Passam, Freda, Spring, Kevin, Skarratt, Kristen, Rebeiro, Patricia, Larsen, Stephen, Presgrave, Peter, Stevenson, William, Ling, Silvia, Tiley, Campbell, Fuller, Stephen, Roncolato, Fernando, Enjeti, Anoop, Hoenemann, Dirk, Lemech, Charlotte, Curtis, David, Bohlander, Stefan, Olivier, Jake, Hertzberg, Mark, Unnikrishnan, Ashwin, Polizotto, Mark, Pimanda, John

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Shared roles for Scl and Lyl1 in murine platelet production and function von Chiu, Sung K., Orive, Stephanie L., Moon, Mitchell J., Saw, Jesslyn, Ellis, Sarah, Kile, Benjamin T., Huang, Yizhou, Chacon, Diego, Pimanda, John E., Beck, Dominik, Hamilton, Justin R., Tremblay, Cedric S., Curtis, David J.

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Cytokine-mediated endocytosis is crucial for the therapeutic resistance of leukemia-propagating cells von Tremblay, Cedric, Chiu, Sung Kai, Saw, Jesslyn, Sonderegger, Stefan, Robinson, Phillip, Curtis, David

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Low mtDNA diversity among widespread Australian diamondback moth Plutella xylostella (L.) suggests isolation and a founder effect von SAW, JESSLYN, ENDERSBY, NANCY M., MCKECHNIE, STEPHEN W.

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A novel role for Lyl1 in primitive erythropoiesis von Chiu, Sung K, Saw, Jesslyn, Huang, Yizhou, Sonderegger, Stefan E, Wong, Nicholas C, Powell, David R, Beck, Dominic, Pimanda, John E, Tremblay, Cedric S, Curtis, David J

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Maintenance of primitive haematopoiesis is shared by SCL and LYL1 von Chiu, Sung Kai, Saw, Jesslyn, Huang, Yizhou, Beck, Dominic, Powell, David, Pimanda, John, Tremblay, Cedric, Curtis, David

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