Contributions of human tumor xenografts to anticancer drug development von Sausville, Edward A, Burger, Angelika M

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A Mechanistic Perspective of Monoclonal Antibodies in Cancer Therapy Beyond Target‐Related Effects von Strome, Scott E., Sausville, Edward A., Mann, Dean

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Perifosine, a novel alkylphospholipid, inhibits protein kinase B activation von Kondapaka, Sudhir B, Singh, Sheo S, Dasmahapatra, Girija P, Sausville, Edward A, Roy, Krishnendu K

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Phase I and Pharmacokinetic Study of MS-275, a Histone Deacetylase Inhibitor, in Patients With Advanced and Refractory Solid Tumors or Lymphoma von RYAN, Qin C, HEADLEE, Donna, MELILLO, Giovanni, ELSAYED, Yusri, MONGA, Manish, KALNITSKIY, Mikhail, ZWIEBEL, James, SAUSVILLE, Edward A, ACHARYA, Milin, SPARREBOOM, Alex, TREPEL, Jane B, YE, Joseph, FIGG, William D, HWANG, Kyunghwa, EUN JOO CHUNG, MURGO, Anthony

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Phase I Study of Folate Conjugate EC145 (Vintafolide) in Patients With Refractory Solid Tumors von LORUSSO, Patricia M, EDELMAN, Martin J, LEAMON, Christopher P, MESSMANN, Richard A, SAUSVILLE, Edward A, BEVER, Susan L, FORMAN, Karen M, PILAT, Maryjo, QUINN, Mary F, JING LI, HEATH, Elisabeth I, MALBURG, Lisa M, KLEIN, Patrick J

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Clinical and laboratory studies of the novel cyclin-dependent kinase inhibitor dinaciclib (SCH 727965) in acute leukemias von Gojo, Ivana, Sadowska, Mariola, Walker, Alison, Feldman, Eric J., Iyer, Swaminathan Padmanabhan, Baer, Maria R., Sausville, Edward A., Lapidus, Rena G., Zhang, Da, Zhu, Yali, Jou, Ying-Ming, Poon, Jennifer, Small, Karen, Bannerji, Rajat

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Mammalian target of rapamycin, a molecular target in squamous cell carcinomas of the head and neck von AMORNPHIMOLTHAM, Panomwat, PATEL, Vyomesh, SODHI, Akrit, NIKITAKIS, Nikolaos G, SAUK, John J, SAUSVILLE, Edward A, MOLINOLO, Alfredo A, GUTKIND, J. Silvio

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Synthesis and biological evaluation of novel curcumin analogs as anti-cancer and anti-angiogenesis agents von Adams, Brian K., Ferstl, Eva M., Davis, Matthew C., Herold, Marike, Kurtkaya, Serdar, Camalier, Richard F., Hollingshead, Melinda G., Kaur, Gurmeet, Sausville, Edward A., Rickles, Frederick R., Snyder, James P., Liotta, Dennis C., Shoji, Mamoru

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Relapsed Philadelphia Chromosome-Positive Pre-B-ALL after CD19-Directed CAR-T Cell Therapy Successfully Treated with Combination of Blinatumomab and Ponatinib von El Chaer, Firas, Holtzman, Noa G., Sausville, Edward A., Law, Jennie Y., Lee, Seung Tae, Duong, Vu H., Baer, Maria R. , Koka, Rima, Singh, Zeba N., Hardy, Nancy M., Emadi, Ashkan

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Safety, Efficacy, Pharmacokinetics, and Pharmacodynamics of the Combination of Sorafenib and Tanespimycin von VAISHAMPAYAN, Ulka N, BURGER, Angelika M, SAUSVILLE, Edward A, HEILBRUN, Lance K, JING LI, HORIBA, M. Naomi, EGORIN, Merrill J, IVY, Percy, PACEY, Simon, LORUSSO, Patricia M

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Preclinical Studies of Vorinostat (Suberoylanilide Hydroxamic Acid) Combined with Cytosine Arabinoside and Etoposide for Treatment of Acute Leukemias von SHIOZAWA, Ken, NAKANISHI, Takeo, MING TAN, FANG, Hong-Bin, WANG, Wen-Chyi, EDELMAN, Martin J, CARLTON, David, GOJO, Ivana, SAUSVILLE, Edward A, ROSS, Douglas D

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In vivo antitumor efficacy of 17-DMAG (17-dimethylaminoethylamino-17-demethoxygeldanamycin hydrochloride), a water-soluble geldanamycin derivative von HOLLINGSHEAD, Melinda, ALLEY, Michael, BURGER, Angelika M, BORGEL, Suzanne, PACULA-COX, Christine, FIEBIG, Heinz-Herbert, SAUSVILLE, Edward A

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Comparison of 17-dimethylaminoethylamino-17-demethoxy-geldanamycin (17DMAG) and 17-allylamino-17-demethoxygeldanamycin (17AAG) in vitro: effects on Hsp90 and client proteins in mel... von SMITH, Victoria, SAUSVILLE, Edward A, CAMALIER, Richard F, FIEBIG, Heinz-Herbert, BURGER, Angelika M

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Issues and progress with protein kinase inhibitors for cancer treatment von Dancey, Janet, Sausville, Edward A

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Akt Plays a Central Role in Sarcomagenesis Induced by Kaposi's Sarcoma Herpesvirus-Encoded G Protein-Coupled Receptor von Sodhi, Akrit, Montaner, Silvia, Patel, Vyomesh, Gómez-Román, José Javier, Li, Yi, Sausville, Edward A., Sawai, Earl T., Gutkind, J. Silvio, Varmus, Harold E.

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Phase I Trial of 72-Hour Continuous Infusion UCN-01 in Patients With Refractory Neoplasms von SAUSVILLE, Edward A, ARBUCK, Susan G, JING, Xiu-Xian, ROBERGE, Michel, FUSE, Eiichi, KUWABARA, Takashi, SENDEROWICZ, Adrian M, MESSMANN, Richard, HEADLEE, Donna, BAUER, Kenneth S, LUSH, Richard M, MURGO, Anthony, FIGG, William D, LAHUSEN, Tyler, JAKEN, Susan

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Biochemical Correlates of mTOR Inhibition by the Rapamycin Ester CCI-779 and Tumor Growth Inhibition von DUDKIN, Lorina, DILLING, Michael B, CHESHIRE, Pamela J, HARWOOD, Franklin C, HOLLINGSHEAD, Melinda, ARBUCK, Susan G, TRAVIS, Robert, SAUSVILLE, Edward A, HOUGHTON, Peter J

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Review of UCN-01 Development: A Lesson in the Importance of Clinical Pharmacology von Fuse, Eiichi, Kuwabara, Takashi, Sparreboom, Alex, Sausville, Edward A., Figg, William D.

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Antitumor Benzothiazoles. 8. Synthesis, Metabolic Formation, and Biological Properties of the C- and N-Oxidation Products of Antitumor 2-(4-Aminophenyl)benzothiazoles von Kashiyama, Eiji, Hutchinson, Ian, Chua, Mei-Sze, Stinson, Sherman F, Phillips, Lawrence R, Kaur, Gurmeet, Sausville, Edward A, Bradshaw, Tracey D, Westwell, Andrew D, Stevens, Malcolm F. G

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Asparaginase in the treatment of non-ALL hematologic malignancies von Emadi, Ashkan, Zokaee, Hania, Sausville, Edward A.

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