Contributions of human tumor xenografts to anticancer drug development von Sausville, Edward A, Burger, Angelika M

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Issues and progress with protein kinase inhibitors for cancer treatment von Dancey, Janet, Sausville, Edward A

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Relationships between drug activity in NCI preclinical in vitro and in vivo models and early clinical trials von Johnson, J I, Decker, S, Zaharevitz, D, Rubinstein, L V, Venditti, J M, Schepartz, S, Kalyandrug, S, Christian, M, Arbuck, S, Hollingshead, M, Sausville, E A

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Perifosine, a novel alkylphospholipid, inhibits protein kinase B activation von Kondapaka, Sudhir B, Singh, Sheo S, Dasmahapatra, Girija P, Sausville, Edward A, Roy, Krishnendu K

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Phase I and Pharmacokinetic Study of MS-275, a Histone Deacetylase Inhibitor, in Patients With Advanced and Refractory Solid Tumors or Lymphoma von RYAN, Qin C, HEADLEE, Donna, MELILLO, Giovanni, ELSAYED, Yusri, MONGA, Manish, KALNITSKIY, Mikhail, ZWIEBEL, James, SAUSVILLE, Edward A, ACHARYA, Milin, SPARREBOOM, Alex, TREPEL, Jane B, YE, Joseph, FIGG, William D, HWANG, Kyunghwa, EUN JOO CHUNG, MURGO, Anthony

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Proteasome inhibitors : A novel class of potent and effective antitumor agents von ADAMS, J, PALOMBELLA, V. J, SAUSVILLE, E. A, JOHNSON, J, DESTREE, A, LAZARUS, D. D, MAAS, J, PIEN, C. S, PRAKASH, S, ELLIOTT, P. J

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Developmental Therapeutics Program at the NCI: molecular target and drug discovery process von MONGA, M, SAUSVILLE, E. A

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A Mechanistic Perspective of Monoclonal Antibodies in Cancer Therapy Beyond Target‐Related Effects von Strome, Scott E., Sausville, Edward A., Mann, Dean

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A gene expression database for the molecular pharmacology of cancer von Brown, Patrick O, Weinstein, John N, Scherf, Uwe, Ross, Douglas T, Waltham, Mark, Smith, Lawrence H, Lee, Jae K, Tanabe, Lorraine, Kohn, Kurt W, Reinhold, William C, Myers, Timothy G, Andrews, Darren T, Scudiero, Dominic A, Eisen, Michael B, Sausville, Edward A, Pommier, Yves, Botstein, David

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Mammalian target of rapamycin, a molecular target in squamous cell carcinomas of the head and neck von AMORNPHIMOLTHAM, Panomwat, PATEL, Vyomesh, SODHI, Akrit, NIKITAKIS, Nikolaos G, SAUK, John J, SAUSVILLE, Edward A, MOLINOLO, Alfredo A, GUTKIND, J. Silvio

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Phase I Study of Folate Conjugate EC145 (Vintafolide) in Patients With Refractory Solid Tumors von LORUSSO, Patricia M, EDELMAN, Martin J, LEAMON, Christopher P, MESSMANN, Richard A, SAUSVILLE, Edward A, BEVER, Susan L, FORMAN, Karen M, PILAT, Maryjo, QUINN, Mary F, JING LI, HEATH, Elisabeth I, MALBURG, Lisa M, KLEIN, Patrick J

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Synthesis and biological evaluation of novel curcumin analogs as anti-cancer and anti-angiogenesis agents von Adams, Brian K., Ferstl, Eva M., Davis, Matthew C., Herold, Marike, Kurtkaya, Serdar, Camalier, Richard F., Hollingshead, Melinda G., Kaur, Gurmeet, Sausville, Edward A., Rickles, Frederick R., Snyder, James P., Liotta, Dennis C., Shoji, Mamoru

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Phase I Trial of 72-Hour Continuous Infusion UCN-01 in Patients With Refractory Neoplasms von SAUSVILLE, Edward A, ARBUCK, Susan G, JING, Xiu-Xian, ROBERGE, Michel, FUSE, Eiichi, KUWABARA, Takashi, SENDEROWICZ, Adrian M, MESSMANN, Richard, HEADLEE, Donna, BAUER, Kenneth S, LUSH, Richard M, MURGO, Anthony, FIGG, William D, LAHUSEN, Tyler, JAKEN, Susan

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Clinical and laboratory studies of the novel cyclin-dependent kinase inhibitor dinaciclib (SCH 727965) in acute leukemias von Gojo, Ivana, Sadowska, Mariola, Walker, Alison, Feldman, Eric J., Iyer, Swaminathan Padmanabhan, Baer, Maria R., Sausville, Edward A., Lapidus, Rena G., Zhang, Da, Zhu, Yali, Jou, Ying-Ming, Poon, Jennifer, Small, Karen, Bannerji, Rajat

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Preclinical and Clinical Development of Cyclin-Dependent Kinase Modulators von Senderowicz, Adrian M., Sausville, Edward A.

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The Chk1 Protein Kinase and the Cdc25C Regulatory Pathways Are Targets of the Anticancer Agent UCN-01 von Graves, Paul R., Yu, Lijia, Schwarz, Julie K., Gales, Janis, Sausville, Edward A., O'Connor, Patrick M., Piwnica-Worms, Helen

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Akt Plays a Central Role in Sarcomagenesis Induced by Kaposi's Sarcoma Herpesvirus-Encoded G Protein-Coupled Receptor von Sodhi, Akrit, Montaner, Silvia, Patel, Vyomesh, Gómez-Román, José Javier, Li, Yi, Sausville, Edward A., Sawai, Earl T., Gutkind, J. Silvio, Varmus, Harold E.

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Paullones, a Series of Cyclin-Dependent Kinase Inhibitors:  Synthesis, Evaluation of CDK1/Cyclin B Inhibition, and in Vitro Antitumor Activity von Schultz, Christiane, Link, Andreas, Leost, Maryse, Zaharevitz, Daniel W, Gussio, Rick, Sausville, Edward A, Meijer, Laurent, Kunick, Conrad

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Antitumor Benzothiazoles. 8. Synthesis, Metabolic Formation, and Biological Properties of the C- and N-Oxidation Products of Antitumor 2-(4-Aminophenyl)benzothiazoles von Kashiyama, Eiji, Hutchinson, Ian, Chua, Mei-Sze, Stinson, Sherman F, Phillips, Lawrence R, Kaur, Gurmeet, Sausville, Edward A, Bradshaw, Tracey D, Westwell, Andrew D, Stevens, Malcolm F. G

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Biochemical Correlates of mTOR Inhibition by the Rapamycin Ester CCI-779 and Tumor Growth Inhibition von DUDKIN, Lorina, DILLING, Michael B, CHESHIRE, Pamela J, HARWOOD, Franklin C, HOLLINGSHEAD, Melinda, ARBUCK, Susan G, TRAVIS, Robert, SAUSVILLE, Edward A, HOUGHTON, Peter J

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