The genomic landscape of response to EGFR blockade in colorectal cancer von Bertotti, Andrea, Papp, Eniko, Jones, Siân, Adleff, Vilmos, Anagnostou, Valsamo, Lupo, Barbara, Sausen, Mark, Phallen, Jillian, Hruban, Carolyn A., Tokheim, Collin, Niknafs, Noushin, Nesselbush, Monica, Lytle, Karli, Sassi, Francesco, Cottino, Francesca, Migliardi, Giorgia, Zanella, Eugenia R., Ribero, Dario, Russolillo, Nadia, Mellano, Alfredo, Muratore, Andrea, Paraluppi, Gianluca, Salizzoni, Mauro, Marsoni, Silvia, Kragh, Michael, Lantto, Johan, Cassingena, Andrea, Li, Qing Kay, Karchin, Rachel, Scharpf, Robert, Sartore-Bianchi, Andrea, Siena, Salvatore, Diaz, Luis A., Trusolino, Livio, Velculescu, Victor E.

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Amplification of the MET receptor drives resistance to anti-EGFR therapies in colorectal cancer von Bardelli, Alberto, Corso, Simona, Bertotti, Andrea, Hobor, Sebastijan, Valtorta, Emanuele, Siravegna, Giulia, Sartore-Bianchi, Andrea, Scala, Elisa, Cassingena, Andrea, Zecchin, Davide, Apicella, Maria, Migliardi, Giorgia, Galimi, Francesco, Lauricella, Calogero, Zanon, Carlo, Perera, Timothy, Veronese, Silvio, Corti, Giorgio, Amatu, Alessio, Gambacorta, Marcello, Diaz, Jr, Luis A, Sausen, Mark, Velculescu, Victor E, Comoglio, Paolo, Trusolino, Livio, Di Nicolantonio, Federica, Giordano, Silvia, Siena, Salvatore

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Somatic mutations of SUZ12 in malignant peripheral nerve sheath tumors von Zhang, Ming, Wang, Yuxuan, Jones, Sian, Sausen, Mark, McMahon, Kevin, Sharma, Rajni, Wang, Qing, Belzberg, Allan J, Chaichana, Kaisorn, Gallia, Gary L, Gokaslan, Ziya L, Riggins, Greg J, Wolinksy, Jean-Paul, Wood, Laura D, Montgomery, Elizabeth A, Hruban, Ralph H, Kinzler, Kenneth W, Papadopoulos, Nickolas, Vogelstein, Bert, Bettegowda, Chetan

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Whole-Exome Sequencing of Salivary Gland Mucoepidermoid Carcinoma von Kang, Hyunseok, Tan, Marietta, Bishop, Justin A, Jones, Siân, Sausen, Mark, Ha, Patrick K, Agrawal, Nishant

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Liquid biopsy approaches to capture tumor evolution and clinical outcomes during cancer immunotherapy von Sivapalan, Lavanya, Murray, Joseph C, Canzoniero, Jenna VanLiere, Landon, Blair, Jackson, Jennifer, Scott, Susan, Lam, Vincent, Levy, Benjamin P., Sausen, Mark, Anagnostou, Valsamo

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Whole-Genome Sequencing of Salivary Gland Adenoid Cystic Carcinoma von Rettig, Eleni M, Talbot, Jr, C Conover, Sausen, Mark, Jones, Sian, Bishop, Justin A, Wood, Laura D, Tokheim, Collin, Niknafs, Noushin, Karchin, Rachel, Fertig, Elana J, Wheelan, Sarah J, Marchionni, Luigi, Considine, Michael, Ling, Shizhang, Fakhry, Carole, Papadopoulos, Nickolas, Kinzler, Kenneth W, Vogelstein, Bert, Ha, Patrick K, Agrawal, Nishant

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Clinical study of genomic drivers in pancreatic ductal adenocarcinoma von Barrett, Michael T, Deiotte, Ray, Lenkiewicz, Elizabeth, Malasi, Smriti, Holley, Tara, Evers, Lisa, Posner, Richard G, Jones, Timothy, Han, Haiyong, Sausen, Mark, Velculescu, Victor E, Drebin, Jeffrey, O'Dwyer, Peter, Jameson, Gayle, Ramanathan, Ramesh K, Von Hoff, Daniel D

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Case report: Single gene testing and comprehensive genomic profiling in non-small cell lung cancer-a case series of divergent results from a large reference laboratory von Strickland, Kyle C, Nesline, Mary K, Previs, Rebecca A, Ko, Heidi, Cooper, Maureen, Rushton, Jennifer R, Wallen, Zachary D, Pabla, Sarabjot, Conroy, Jeffrey M, Sausen, Mark, Saini, Kamal S, Cantini, Luca, Jensen, Taylor J, Caveney, Brian J, Eisenberg, Marcia, Severson, Eric A, Ramkissoon, Shakti

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TMB standardization by alignment to reference standards: Phase II of the Friends of Cancer Research TMB Harmonization Project von Merino, Diana M., McShane, Lisa, Butler, Matt, Funari, Vincent Anthony, Hellmann, Matthew David, Chaudhary, Ruchi, Chen, Shu-Jen, Chen, Wangjuh Sting, Conroy, Jeffrey M., Fabrizio, David, MacConaill, Laura E, Pallavajjala, Aparna, Papin, Arnaud, Sausen, Mark, Weigman, Victor J, Xie, Mingchao, Zehir, Ahmet, Zhao, Chen, Williams, Paul M.

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Abstract CN02-02: Comprehensive detection of structural alterations in the circulation of cancer patients von Sausen, Mark

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Advancing Evidence Generation for Circulating Tumor DNA: Lessons Learned from A Multi-Assay Study of Baseline Circulating Tumor DNA Levels across Cancer Types and Stages von McKelvey, Brittany A, Andrews, Hillary S, Baehner, Frederick L, Chen, James, Espenschied, Carin R, Fabrizio, David, Gorton, Vanessa, Gould, Claire, Guinney, Justin, Jones, Greg, Lv, Xiangyang, Nahorski, Michael S, Palomares, Melanie R, Pestano, Gary A, Sausen, Mark, Silk, Alain, Zhang, Nicole, Zhang, Zhihong, Stewart, Mark D, Allen, Jeff D

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Neoadjuvant Nivolumab plus Chemotherapy in Resectable Lung Cancer von Forde, Patrick M., Spicer, Jonathan, Lu, Shun, Provencio, Mariano, Mitsudomi, Tetsuya, Awad, Mark M., Felip, Enriqueta, Broderick, Stephen R., Brahmer, Julie R., Swanson, Scott J., Kerr, Keith, Wang, Changli, Ciuleanu, Tudor-Eliade, Saylors, Gene B., Tanaka, Fumihiro, Ito, Hiroyuki, Chen, Ke-Neng, Liberman, Moishe, Vokes, Everett E., Taube, Janis M., Dorange, Cecile, Cai, Junliang, Fiore, Joseph, Jarkowski, Anthony, Balli, David, Sausen, Mark, Pandya, Dimple, Calvet, Christophe Y., Girard, Nicolas

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Abstract PL06-03: Detection of chromosomal alterations in the circulation of cancer patients with whole-genome sequencing von Sausen, Mark

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Neoadjuvant Nivolumab plus Chemotherapy in Resectable Lung Cancer von Forde, Patrick M., Spicer, Jonathan, Lu, Shun, Provencio, Mariano, Mitsudomi, Tetsuya, Awad, Mark M., Felip, Enriqueta, Broderick, Stephen R., Brahmer, Julie R., Swanson, Scott J., Kerr, Keith, Wang, Changli, Ciuleanu, Tudor-Eliade, Saylors, Gene B., Tanaka, Fumihiro, Ito, Hiroyuki, Chen, Ke-Neng, Liberman, Moishe, Vokes, Everett E., Taube, Janis M., Dorange, Cecile, Cai, Junliang, Fiore, Joseph, Jarkowski, Anthony, Balli, David, Sausen, Mark, Pandya, Dimple, Calvet, Christophe Y., Girard, Nicolas

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Abstract 5606: Detection of circulating tumor DNA in early and late stage human malignancies von Bettegowda, Chetan, Sausen, Mark, Leary, Rebecca, Kinde, Isaac, Agrawal, Nishant, Bartlett, Bjarne, Wang, Hao, Luber, Brandon, Kinzler, Kenneth, Vogelstein, Bert, Papadopoulos, Nickolas, Diaz, Luis

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Homologous Recombination Deficiency: Concepts, Definitions, and Assays von Stewart, Mark D, Merino Vega, Diana, Arend, Rebecca C, Baden, Jonathan F, Barbash, Olena, Beaubier, Nike, Collins, Grace, French, Tim, Ghahramani, Negar, Hinson, Patsy, Jelinic, Petar, Marton, Matthew J, McGregor, Kimberly, Parsons, Jerod, Ramamurthy, Lakshman, Sausen, Mark, Sokol, Ethan S, Stenzinger, Albrecht, Stires, Hillary, Timms, Kirsten M, Turco, Diana, Wang, Iris, Williams, J Andrew, Wong-Ho, Elaine, Allen, Jeff

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The Effect of Preservative and Temperature on the Analysis of Circulating Tumor DNA von Parpart-Li, Sonya, Bartlett, Bjarne, Popoli, Maria, Adleff, Vilmos, Tucker, Laura, Steinberg, Rebecca, Georgiadis, Andrew, Phallen, Jill, Brahmer, Julie, Azad, Nilo, Browner, Ilene, Laheru, Daniel, Velculescu, Victor E, Sausen, Mark, Diaz, Jr, Luis A

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Noninvasive Detection of Microsatellite Instability and High Tumor Mutation Burden in Cancer Patients Treated with PD-1 Blockade von Georgiadis, Andrew, Durham, Jennifer N, Keefer, Laurel A, Bartlett, Bjarne R, Zielonka, Magdalena, Murphy, Derek, White, James R, Lu, Steve, Verner, Ellen L, Ruan, Finey, Riley, David, Anders, Robert A, Gedvilaite, Erika, Angiuoli, Sam, Jones, Siân, Velculescu, Victor E, Le, Dung T, Diaz, Jr, Luis A, Sausen, Mark

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ctDNA response after pembrolizumab in non-small cell lung cancer: phase 2 adaptive trial results von Anagnostou, Valsamo, Ho, Cheryl, Nicholas, Garth, Juergens, Rosalyn Anne, Sacher, Adrian, Fung, Andrea S., Wheatley-Price, Paul, Laurie, Scott A., Levy, Benjamin, Brahmer, Julie R., Balan, Archana, Niknafs, Noushin, Avrutin, Egor, Zhu, Liting, Sausen, Mark, Bradbury, Penelope A., O’Donnell-Tormey, Jill, Gaudreau, Pierre Olivier, Ding, Keyue, Dancey, Janet

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Integrated genomic analyses identify ARID1A and ARID1B alterations in the childhood cancer neuroblastoma von Sausen, Mark, Leary, Rebecca J, Jones, Siân, Wu, Jian, Reynolds, C Patrick, Liu, Xueyuan, Blackford, Amanda, Parmigiani, Giovanni, Diaz, Luis A, Papadopoulos, Nickolas, Vogelstein, Bert, Kinzler, Kenneth W, Velculescu, Victor E, Hogarty, Michael D

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