Use of CRISPR-modified human stem cell organoids to study the origin of mutational signatures in cancer von Drost, Jarno, van Boxtel, Ruben, Blokzijl, Francis, Mizutani, Tomohiro, Sasaki, Nobuo, Sasselli, Valentina, de Ligt, Joep, Behjati, Sam, Grolleman, Judith E., van Wezel, Tom, Nik-Zainal, Serena, Kuiper, Roland P., Cuppen, Edwin, Clevers, Hans

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Somatic inflammatory gene mutations in human ulcerative colitis epithelium von Nanki, Kosaku, Fujii, Masayuki, Shimokawa, Mariko, Matano, Mami, Nishikori, Shingo, Date, Shoichi, Takano, Ai, Toshimitsu, Kohta, Ohta, Yuki, Takahashi, Sirirat, Sugimoto, Shinya, Ishimaru, Kazuhiro, Kawasaki, Kenta, Nagai, Yoko, Ishii, Ryota, Yoshida, Kosuke, Sasaki, Nobuo, Hibi, Toshifumi, Ishihara, Soichiro, Kanai, Takanori, Sato, Toshiro

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Development of a Scalable Coculture System for Gut Anaerobes and Human Colon Epithelium von Sasaki, Nobuo, Miyamoto, Kentaro, Maslowski, Kendle M., Ohno, Hiroshi, Kanai, Takanori, Sato, Toshiro

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Functional Repair of CFTR by CRISPR/Cas9 in Intestinal Stem Cell Organoids of Cystic Fibrosis Patients von Schwank, Gerald, Koo, Bon-Kyoung, Sasselli, Valentina, Dekkers, Johanna F., Heo, Inha, Demircan, Turan, Sasaki, Nobuo, Boymans, Sander, Cuppen, Edwin, van der Ent, Cornelis K., Nieuwenhuis, Edward E.S., Beekman, Jeffrey M., Clevers, Hans

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In vitro expansion of single Lgr5+ liver stem cells induced by Wnt-driven regeneration von Huch, Meritxell, Dorrell, Craig, Boj, Sylvia F., van Es, Johan H., Li, Vivian S. W., van de Wetering, Marc, Sato, Toshiro, Hamer, Karien, Sasaki, Nobuo, Finegold, Milton J., Haft, Annelise, Vries, Robert G., Grompe, Markus, Clevers, Hans

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Automated brightfield morphometry of 3D organoid populations by OrganoSeg von Borten, Michael A., Bajikar, Sameer S., Sasaki, Nobuo, Clevers, Hans, Janes, Kevin A.

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Continuous-Wave Laser Lateral Crystallization of A-Si Thin Films on Polyimide Using a Heatsink Layer Embedded in the Buffer SiO2 von Sasaki, Nobuo, Arif, Muhammad, Uraoka, Yukiharu, Gotoh, Jun, Sugimoto, Shigeto

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Extension of the {100}-Oriented Grain-Boundary Free Si Thin Film Grown by a Continuous-Wave Laser Lateral Crystallization von Arif, Muhammad, Sasaki, Nobuo, Ishikawa, Yasuaki, Uraoka, Yukiharu

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Long-Term Culture of Genome-Stable Bipotent Stem Cells from Adult Human Liver von Huch, Meritxell, Gehart, Helmuth, van Boxtel, Ruben, Hamer, Karien, Blokzijl, Francis, Verstegen, Monique M.A., Ellis, Ewa, van Wenum, Martien, Fuchs, Sabine A., de Ligt, Joep, van de Wetering, Marc, Sasaki, Nobuo, Boers, Susanne J., Kemperman, Hans, de Jonge, Jeroen, Ijzermans, Jan N.M., Nieuwenhuis, Edward E.S., Hoekstra, Ruurdtje, Strom, Stephen, Vries, Robert R.G., van der Laan, Luc J.W., Cuppen, Edwin, Clevers, Hans

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Association of Insulin Resistance, Plasma Glucose Level, and Serum Insulin Level With Hypertension in a Population With Different Stages of Impaired Glucose Metabolism von Sasaki, Nobuo, Ozono, Ryoji, Higashi, Yukihito, Maeda, Ryo, Kihara, Yasuki

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Dll1+ secretory progenitor cells revert to stem cells upon crypt damage von van Es, Johan H., Sato, Toshiro, van de Wetering, Marc, Lyubimova, Anna, Yee Nee, Annie Ng, Gregorieff, Alex, Sasaki, Nobuo, Zeinstra, Laura, van den Born, Maaike, Korving, Jeroen, Martens, Anton C. M., Barker, Nick, van Oudenaarden, Alexander, Clevers, Hans

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Adipose tissue insulin resistance predicts the incidence of hypertension: The Hiroshima Study on Glucose Metabolism and Cardiovascular Diseases von Sasaki, Nobuo, Maeda, Ryo, Ozono, Ryoji, Yoshimura, Kenichi, Nakano, Yukiko, Higashi, Yukihito

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Enteroendocrine and tuft cells support Lgr5 stem cells on Paneth cell depletion von van Es, Johan H., Wiebrands, Kay, López-Iglesias, Carmen, van de Wetering, Marc, Zeinstra, Laura, van den Born, Maaike, Korving, Jeroen, Sasaki, Nobuo, Peters, Peter J., van Oudenaarden, Alexander, Clevers, Hans

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Reg4⁺ deep crypt secretory cells function as epithelial niche for Lgr5⁺ stem cells in colon von Sasaki, Nobuo, Sachs, Norman, Wiebrands, Kay, Ellenbroek, Saskia I. J., Fumagalli, Arianna, Lyubimova, Anna, Begthel, Harry, van den Born, Maaike, van Es, Johan H., Karthaus, Wouter R., Li, Vivian S. W., López-Iglesias, Carmen, Peters, Peter J., van Rheenen, Jacco, van Oudenaarden, Alexander, Clevers, Hans

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Association of Flow Parameters and Diameter in the Common Carotid Artery with Impaired Glucose Metabolism von Sasaki, Nobuo, Maeda, Ryo, Ozono, Ryoji, Nakano, Yukiko, Higashi, Yukihito

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Ongoing chromosomal instability and karyotype evolution in human colorectal cancer organoids von Bolhaqueiro, Ana C. F., Ponsioen, Bas, Bakker, Bjorn, Klaasen, Sjoerd J., Kucukkose, Emre, van Jaarsveld, Richard H., Vivié, Judith, Verlaan-Klink, Ingrid, Hami, Nizar, Spierings, Diana C. J., Sasaki, Nobuo, Dutta, Devanjali, Boj, Sylvia F., Vries, Robert G. J., Lansdorp, Peter M., van de Wetering, Marc, van Oudenaarden, Alexander, Clevers, Hans, Kranenburg, Onno, Foijer, Floris, Snippert, Hugo J. G., Kops, Geert J. P. L.

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Associations Between Characteristics of Obstructive Sleep Apnea and Nocturnal Blood Pressure Surge von Sasaki, Nobuo, Nagai, Michiaki, Mizuno, Hiroyuki, Kuwabara, Mitsuo, Hoshide, Satoshi, Kario, Kazuomi

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Gut pathobionts underlie intestinal barrier dysfunction and liver T helper 17 cell immune response in primary sclerosing cholangitis von Nakamoto, Nobuhiro, Sasaki, Nobuo, Aoki, Ryo, Miyamoto, Kentaro, Suda, Wataru, Teratani, Toshiaki, Suzuki, Takahiro, Koda, Yuzo, Chu, Po-Sung, Taniki, Nobuhito, Yamaguchi, Akihiro, Kanamori, Mitsuhiro, Kamada, Nobuhiko, Hattori, Masahira, Ashida, Hiroshi, Sakamoto, Michiie, Atarashi, Koji, Narushima, Seiko, Yoshimura, Akihiko, Honda, Kenya, Sato, Toshiro, Kanai, Takanori

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Defining the Identity and Dynamics of Adult Gastric Isthmus Stem Cells von Han, Seungmin, Fink, Juergen, Jörg, David J., Lee, Eunmin, Yum, Min Kyu, Chatzeli, Lemonia, Merker, Sebastian R., Josserand, Manon, Trendafilova, Teodora, Andersson-Rolf, Amanda, Dabrowska, Catherine, Kim, Hyunki, Naumann, Ronald, Lee, Ji-Hyun, Sasaki, Nobuo, Mort, Richard Lester, Basak, Onur, Clevers, Hans, Stange, Daniel E., Philpott, Anna, Kim, Jong Kyoung, Simons, Benjamin D., Koo, Bon-Kyoung

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DNA damage‐induced cellular senescence is regulated by 53BP1 accumulation in the nuclear foci and phase separation von Oda, Tsukasa, Gotoh, Nanami, Kasamatsu, Tetsuhiro, Handa, Hiroshi, Saitoh, Takayuki, Sasaki, Nobuo

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