Preclinical evaluation of multiple species of PEGylated recombinant phenylalanine ammonia lyase for the treatment of phenylketonuria von Sarkissian, Christineh N, Gámez, Alejandra, Wang, Lin, Charbonneau, Marilyse, Fitzpatrick, Paul, Lemontt, Jeffrey F, Zhao, Bin, Vellard, Michael, Bell, Sean M, Henschell, Carroll, Lambert, Amy, Tsuruda, Laurie, Stevens, Raymond C, Scriver, Charles R

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Phenylalanine ammonia lyase (PAL): From discovery to enzyme substitution therapy for phenylketonuria von Levy, Harvey L., Sarkissian, Christineh N., Scriver, Charles R.

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In memoriam: Charles Robert Scriver, CM, CC, GOQ, FRS, FRSC (1930–2023) von Levy, Harvey L., Sarkissian, Christineh N.

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Charles Scriver: Epitome of the physician scientist von Sarkissian, Christineh N., Scriver, Paul P., Prevost, Lynne, Levy, Harvey L.

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Structural and Biochemical Characterization of the Therapeutic Anabaena variabilis Phenylalanine Ammonia Lyase von Wang, Lin, Gamez, Alejandra, Archer, Holly, Abola, Enrique E., Sarkissian, Christineh N., Fitzpatrick, Paul, Wendt, Dan, Zhang, Yanhong, Vellard, Michel, Bliesath, Joshua, Bell, Sean M., Lemontt, Jeffrey F., Scriver, Charles R., Stevens, Raymond C.

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Phenylalanine ammonia lyase, enzyme substitution therapy for phenylketonuria, where are we now? von Sarkissian, Christineh N., Gámez, Alejandra

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A Different Approach to Treatment of Phenylketonuria: Phenylalanine Degradation with Recombinant Phenylalanine Ammonia Lyase von Sarkissian, Christineh N., Shao, Zhongqi, Blain, Francoise, Peevers, Rosalie, Su, Hongsheng, Heft, Robert, Thomas M. S. Chang, Scriver, Charles R.

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What we know that could influence future treatment of phenylketonuria von Sarkissian, C. N, Gámez, A, Scriver, C. R

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p27 , a novel protein in St John's Wort, that suppresses expression of HIV-1 genome von Darbinian-Sarkissian, N, Darbinyan, A, Otte, J, Radhakrishnan, S, Sawaya, B E, Arzumanyan, A, Chipitsyna, G, Popov, Y, Rappaport, J, Amini, S, Khalili, K

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Tetrahydrobiopterin treatment reduces brain L-Phe but only partially improves serotonin in hyperphenylalaninemic ENU1/2 mice von Scherer, Tanja, Allegri, Gabriella, Sarkissian, Christineh N., Ying, Ming, Grisch-Chan, Hiu Man, Rassi, Anahita, Winn, Shelley R., Harding, Cary O., Martinez, Aurora, Thöny, Beat

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Evaluation of orally administered PEGylated phenylalanine ammonia lyase in mice for the treatment of Phenylketonuria von Sarkissian, Christineh N., Kang, Tse Siang, Gámez, Alejandra, Scriver, Charles R., Stevens, Raymond C.

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Quantitation of phenylalanine and its trans-cinnamic, benzoic and hippuric acid metabolites in biological fluids in a single GC-MS analysis von Sarkissian, Christineh N., Scriver, Charles R., Mamer, Orval A.

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Converting an injectable protein therapeutic into an oral form: Phenylalanine ammonia lyase for phenylketonuria von Kang, Tse Siang, Wang, Lin, Sarkissian, Christineh N., Gámez, Alejandra, Scriver, Charles R., Stevens, Raymond C.

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The mechanism of BH4-responsive hyperphenylalaninemia-As it occurs in the ENU1/2 genetic mouse model von Sarkissian, Christineh N., Ying, Ming, Scherer, Tanja, Thöny, Beat, Martinez, Aurora

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Structure-based chemical modification strategy for enzyme replacement treatment of phenylketonuria von Wang, Lin, Gamez, Alejandra, Sarkissian, Christineh N., Straub, Mary, Patch, Marianne G., Han, Gye Won, Striepeke, Steve, Fitzpatrick, Paul, Scriver, Charles R., Stevens, Raymond C.

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Development of pegylated forms of recombinant Rhodosporidium toruloides phenylalanine ammonia-lyase for the treatment of classical phenylketonuria von Gámez, Alejandra, Sarkissian, Christineh N, Wang, Lin, Kim, Woomi, Straub, Mary, Patch, Marianne G, Chen, Lin, Striepeke, Steve, Fitzpatrick, Paul, Lemontt, Jeffrey F, O'Neill, Charles, Scriver, Charles R, Stevens, Raymond C

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Crowd-Funded Micro-Grants for Genomics and “Big Data”: An Actionable Idea Connecting Small (Artisan) Science, Infrastructure Science, and Citizen Philanthropy von Özdemir, Vural, Badr, Kamal F., Dove, Edward S., Endrenyi, Laszlo, Geraci, Christy Jo, Hotez, Peter J., Milius, Djims, Neves-Pereira, Maria, Pang, Tikki, Rotimi, Charles N., Sabra, Ramzi, Sarkissian, Christineh N., Srivastava, Sanjeeva, Tims, Hesther, Zgheib, Nathalie K., Kickbusch, Ilona

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O037 Diagnostic Accuracy of OSA Screening Tools for Acute Coronary Syndrome von Tong, B, Dissanayake, H, Patel, S, Skilton, M, McClintock, S, Sutherland, K, Ucak, S, Yee, B, Sarkissian, N, Cistulli, P

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P107 Optimizing Obstructive Sleep Apnea Therapy in Patients with Acute Coronary Syndrome: A Pilot Randomised Controlled Trial von Tong, B, Dissanayake, H, Patel, S, Ucak, S, McClintock, S, Skilton, M, Sutherland, K, Yee, B, Sarkissian, N, Cistulli, P

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P108 Obstructive Sleep Apnoea in Acute Coronary Syndrome: An Observational Study von Tong, B, Dissanayake, H, Patel, S, Ucak, S, Skilton, M, McClintock, S, Sutherland, K, Yee, B, Sarkissian, N, Cistulli, P

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