Cysteine Catabolism: A Novel Metabolic Pathway Contributing to Glioblastoma Growth von PRABHU, Antony, SARCAR, Bhaswati, KAHALI, Soumen, ZHIGANG YUAN, JOHNSON, Joseph J, ADAM, Klaus-Peter, KENSICKI, Elizabeth, CHINNAIYAN, Prakash

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The Metabolomic Signature of Malignant Glioma Reflects Accelerated Anabolic Metabolism von CHINNAIYAN, Prakash, KENSICKI, Elizabeth, BLOOM, Gregory, PRABHU, Antony, SARCAR, Bhaswati, KAHALI, Soumen, ESCHRICH, Steven, XIAOTAO QU, FORSYTH, Peter, GILLIES, Robert

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Establishing a living biobank of patient-derived organoids of intraductal papillary mucinous neoplasms of the pancreas von Beato, Francisca, Reverón, Dayana, Dezsi, Kaleena B., Ortiz, Antonio, Johnson, Joseph O., Chen, Dung-Tsa, Ali, Karla, Yoder, Sean J., Jeong, Daniel, Malafa, Mokenge, Hodul, Pamela, Jiang, Kun, Centeno, Barbara A., Abdalah, Mahmoud A., Balasi, Jodi A., Tassielli, Alexandra F., Sarcar, Bhaswati, Teer, Jamie K., DeNicola, Gina M., Permuth, Jennifer B., Fleming, Jason B.

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CDK4/6 inhibition synergizes with inhibition of P21-Activated Kinases (PAKs) in lung cancer cell lines von Wright, Gabriela M, Gimbrone, Nick T, Sarcar, Bhaswati, Percy, Trent R, Gordián, Edna R, Kinose, Fumi, Sumi, Natália J, Rix, Uwe, Cress, W. Douglas

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Targeting the unfolded protein response in glioblastoma cells with the fusion protein EGF-SubA von Prabhu, Antony, Sarcar, Bhaswati, Kahali, Soumen, Shan, Yuan, Chinnaiyan, Prakash

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Activation of the Unfolded Protein Response Contributes toward the Antitumor Activity of Vorinostat von Kahali, Soumen, Sarcar, Bhaswati, Fang, Bin, Williams, Eli S., Koomen, John M., Tofilon, Philip J., Chinnaiyan, Prakash

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Characterization of epidermal growth factor receptor (EGFR) P848L, an unusual EGFR variant present in lung cancer patients, in a murine Ba/F3 model von Sarcar, Bhaswati, Gimbrone, Nicholas T., Wright, Gabriela, Remsing Rix, Lily L., Gordian, Edna R., Rix, Uwe, Chiappori, Alberto A., Reuther, Gary W., Santiago‐Cardona, Pedro G., Muñoz‐Antonia, Teresita, Cress, William Douglas

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Class I histone deacetylases localize to the endoplasmic reticulum and modulate the unfolded protein response von Kahali, Soumen, Sarcar, Bhaswati, Prabhu, Antony, Seto, Edward, Chinnaiyan, Prakash

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CDK4/6 inhibition synergizes with inhibition of P21-Activated Kinases von Wright, Gabriela M, Gimbrone, Nick T, Sarcar, Bhaswati, Percy, Trent R, Gordián, Edna R, Kinose, Fumi, Sumi, Natália J, Rix, Uwe, Cress, W. Douglas

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Vorinostat enhances the cytotoxic effects of the topoisomerase I inhibitor SN38 in glioblastoma cell lines von Sarcar, Bhaswati, Kahali, Soumen, Chinnaiyan, Prakash

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Targeting radiation-induced G(2) checkpoint activation with the Wee-1 inhibitor MK-1775 in glioblastoma cell lines von Sarcar, Bhaswati, Kahali, Soumen, Prabhu, Antony H, Shumway, Stuart D, Xu, Yang, Demuth, Tim, Chinnaiyan, Prakash

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A comparative Proteomics Analysis Identified Differentially Expressed Proteins in Pancreatic Cancer–Associated Stellate Cell Small Extracellular Vesicles von Sarcar, Bhaswati, Fang, Bin, Izumi, Victoria, O. Nunez Lopez, Yury, Tassielli, Alexandra, Pratley, Richard, Jeong, Daniel, Permuth, Jennifer B., Koomen, John M., Fleming, Jason B., Stewart, Paul A.

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Translational relevance of SOS1 targeting for KRAS‐mutant colorectal cancer von Alem, Diego, Yang, Xinrui, Beato, Francisca, Sarcar, Bhaswati, Tassielli, Alexandra F., Dai, Ruifan, Hogenson, Tara L., Park, Margaret A., Jiang, Kun, Cai, Jianfeng, Yuan, Yu, Fernandez‐Zapico, Martin E., Tan, Aik Choon, Fleming, Jason B., Xie, Hao

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Ras-mediated modulation of pyruvate dehydrogenase activity regulates mitochondrial reserve capacity and contributes to glioblastoma tumorigenesis von Prabhu, Antony, Sarcar, Bhaswati, Miller, C Ryan, Kim, Sung-Hak, Nakano, Ichiro, Forsyth, Peter, Chinnaiyan, Prakash

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Abstract PR03: Somatic mutations and ancestry markers in Hispanic lung cancer patients von Cress, William D., Gimbrone, Nicholas T., Sarcar, Bhaswati, Gordian, Edna, Rivera, Jason I., Lopez, Christian, Teer, Jamie K., Welsh, Eric A., Chiappori, Alberto A., Schabath, Matthew B., Reuther, Gary W., Santiago-Cardona, Pedro G.

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Somatic Mutations and Ancestry Markers in Hispanic Lung Cancer Patients von Gimbrone, Nicholas T., Sarcar, Bhaswati, Gordian, Edna R., Rivera, Jason I., Lopez, Christian, Yoder, Sean J., Teer, Jamie K., Welsh, Eric A., Chiappori, Alberto A., Schabath, Matthew B., Reuther, Gary W., Dutil, Julie, Garcia, Miosotis, Ventosilla-Villanueva, Ronald, Vera-Valdivia, Luis, Yabar-Berrocal, Alejandro, Motta-Guerrero, Rodrigo, Santiago-Cardona, Pedro G., Muñoz-Antonia, Teresita, Cress, W. Douglas

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Phase I trial of vorinostat combined with bevacizumab and CPT-11 in recurrent glioblastoma von Chinnaiyan, Prakash, Chowdhary, Sajeel, Potthast, Lisa, Prabhu, Antony, Tsai, Ya-Yu, Sarcar, Bhaswati, Kahali, Soumen, Brem, Steven, Yu, H. Michael, Rojiani, Amyn, Murtagh, Ryan, Pan, Edward

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Abstract B032: KRAS copy number variation and mutant allele fractions predict in vitro response of PDX-derived human pancreatic cancer cell lines to KRASG12D inhibitor MRTX1133 von Sarcar, Bhaswati, Tassielli, Alexandra, Wang, Liang, Dai, Ruifan, Read, Meagan D., Beato, Francisca, Kim, Dae W., Hodul, Pamela J., Permuth, Jennifer B., Haura, Eric B., Malafa, Mokenge P., Fleming, Jason B.

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Brief Report: Somatic Mutations and Ancestry Markers in Hispanic Lung Cancer Patients von Gimbrone, Nicholas T., Sarcar, Bhaswati, Gordian, Edna R., Rivera, Jason I., Lopez, Christian, Yoder, Sean J., Teer, Jamie K., Welsh, Eric A., Chiaporri, Alberto A., Schabath, Matthew B., Reuther, Gary W., Dutil, Julie, Garcia, Miosotis, Ventosilla-Villanueva, Ronald, Vera-Valdivia, Luis, Yabar-Berrocal, Alejandro, Motta-Guerrero, Rodrigo, Santiago-Cardona, Pedro G., Muñoz-Antonia, Teresita, Cress, W. Douglas

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The Emerging Role of Histone Deacetylases (HDACs) in UPR Regulation von Kahali, Soumen, Sarcar, Bhaswati, Chinnaiyan, Prakash

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