Hydrogel drug delivery system with predictable and tunable drug release and degradation rates von Ashley, Gary W., Henise, Jeff, Reid, Ralph, Santi, Daniel V.

Volltext

Long-Term Stabilization of Maleimide–Thiol Conjugates von Fontaine, Shaun D, Reid, Ralph, Robinson, Louise, Ashley, Gary W, Santi, Daniel V

Volltext

A long-acting C-natriuretic peptide for achondroplasia von Schneider, Eric L, Carreras, Christopher W, Reid, Ralph, Ashley, Gary W, Santi, Daniel V

Volltext

Interleukin 15 Pharmacokinetics and Consumption by a Dynamic Cytokine Sink von Hangasky, John A, Waldmann, Thomas A, Santi, Daniel V

Volltext

A platform technology for ultra-long acting intratumoral therapy von Henise, Jeff, Hangasky, John A., Charych, Deborah, Carreras, Christopher W., Ashley, Gary W., Santi, Daniel V.

Volltext

Predictable and tunable half-life extension of therapeutic agents by controlled chemical release from macromolecular conjugates von Santi, Daniel V, Schneider, Eric L, Reid, Ralph, Robinson, Louise, Ashley, Gary W

Volltext

Synthesis of Methyl Halides from Biomass Using Engineered Microbes von Bayer, Travis S, Widmaier, Daniel M, Temme, Karsten, Mirsky, Ethan A, Santi, Daniel V, Voigt, Christopher A

Volltext

PLX038A, a long-acting SN-38, penetrates the blood-tumor-brain-barrier, accumulates and releases SN-38 in brain tumors to increase survival of tumor bearing mice von Jung, Jinkyu, Schneider, Eric L., Zhang, Wei, Song, Hua, Zhang, Meili, Chou, William, Meher, Niranjan, VanBrocklin, Henry F., Barcellos-Hoff, Mary Helen, Ozawa, Tomoko, Gilbert, Mark R., Santi, Daniel V.

Volltext

Does sacituzumab-govitecan act as a conventional antibody drug conjugate (ADC), a prodrug of SN-38 or both? von Santi, Daniel V., Cabel, Luc, Bidard, François-Clément

Volltext

Species-specific optimization of PEG~SN-38 prodrug pharmacokinetics and antitumor effects in a triple-negative BRCA1-deficient xenograft von Fontaine, Shaun D., Hann, Byron, Reid, Ralph, Ashley, Gary W., Santi, Daniel. V.

Volltext

A very long-acting IL-15: implications for the immunotherapy of cancer von Hangasky, John A, Chen, Wei, Dubois, Sigrid P, Daenthanasanmak, Anusara, Müller, Jürgen R, Reid, Ralph, Waldmann, Thomas A, Santi, Daniel V

Volltext

Leveraging long-acting IL-15 agonists for intratumoral delivery and enhanced antimetastatic activity von Hangasky, John A, Fernández, Rocío Del Valle, Stellas, Dimitris, Hails, Guillermo, Karaliota, Sevasti, Ashley, Gary W, Felber, Barbara K, Pavlakis, George N, Santi, Daniel V

Volltext

Targeted Covalent Inactivation of Protein Kinases by Resorcylic Acid Lactone Polyketides von Schirmer, Andreas, Kennedy, Jonathan, Murli, Sumati, Reid, Ralph, Santi, Daniel V.

Volltext

Total Synthesis of Long DNA Sequences: Synthesis of a Contiguous 32-kb Polyketide Synthase Gene Cluster von Kodumal, Sarah J., Patel, Kedar G., Reid, Ralph, Menzella, Hugo G., Welch, Mark, Santi, Daniel V., Stroud, Robert M.

Volltext

Facile preparation of tetra‐polyethylene glycol hydrogel microspheres for drug delivery by cross‐flow membrane emulsification von Henise, Jeff, Yao, Brian, Ashley, Gary W., Santi, Daniel V.

Volltext

Autoclave sterilization of tetra‐polyethylene glycol hydrogel biomaterials with β‐eliminative crosslinks von Henise, Jeff, Yao, Brian, Ashley, Gary W., Santi, Daniel V.

Volltext

A Model of Structure and Catalysis for Ketoreductase Domains in Modular Polyketide Synthases von Reid, Ralph, Piagentini, Misty, Rodriguez, Eduardo, Ashley, Gary, Viswanathan, Nina, Carney, John, Santi, Daniel V, Hutchinson, C. Richard, McDaniel, Robert

Volltext

The limitation of lipidation: Conversion of semaglutide from once-weekly to once-monthly dosing von Schneider, Eric L, Hangasky, John A, Fernández, Rocío Del Valle, Ashley, Gary W, Santi, Daniel V

Volltext

Antifolate-Resistant Mutants of Plasmodium falciparum Dihydrofolate Reductase von Sirawaraporn, Worachart, Sathitkul, Tanajit, Sirawaraporn, Rachada, Yuthavong, Yongyuth, Santi, Daniel V.

Volltext

Synthesis and biological activities of novel 17-aminogeldanamycin derivatives von Tian, Zong-Qiang, Liu, Yaoquan, Zhang, Dan, Wang, Zhan, Dong, Steven D., Carreras, Christopher W., Zhou, Yiqing, Rastelli, Giulio, Santi, Daniel V., Myles, David C.

Volltext