Alpha-synuclein: Pathology, mitochondrial dysfunction and neuroinflammation in Parkinson’s disease von Rocha, Emily M, De Miranda, Briana, Sanders, Laurie H

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LRRK2 mutations cause mitochondrial DNA damage in iPSC-derived neural cells from Parkinson's disease patients: Reversal by gene correction von Sanders, Laurie H, Laganière, Josée, Cooper, Oliver, Mak, Sally K, Vu, B. Joseph, Huang, Y. Anne, Paschon, David E, Vangipuram, Malini, Sundararajan, Ramya, Urnov, Fyodor D, Langston, J. William, Gregory, Philip D, Zhang, H. Steve, Greenamyre, J. Timothy, Isacson, Ole, Schüle, Birgitt

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Extensive uptake of α-synuclein oligomers in astrocytes results in sustained intracellular deposits and mitochondrial damage von Lindström, Veronica, Gustafsson, Gabriel, Sanders, Laurie H., Howlett, Evan H., Sigvardson, Jessica, Kasrayan, Alex, Ingelsson, Martin, Bergström, Joakim, Erlandsson, Anna

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Synthetic alpha-synuclein fibrils cause mitochondrial impairment and selective dopamine neurodegeneration in part via iNOS-mediated nitric oxide production von Tapias, Victor, Hu, Xiaoping, Luk, Kelvin C., Sanders, Laurie H., Lee, Virginia M., Greenamyre, J. Timothy

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LRRK2 G2019S-induced mitochondrial DNA damage is LRRK2 kinase dependent and inhibition restores mtDNA integrity in Parkinson's disease von Howlett, Evan H, Jensen, Nicholas, Belmonte, Frances, Zafar, Faria, Hu, Xiaoping, Kluss, Jillian, Schüle, Birgitt, Kaufman, Brett A, Greenamyre, J T, Sanders, Laurie H

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DNA damage and repair in Parkinson's disease: Recent advances and new opportunities von Gonzalez‐Hunt, Claudia P., Sanders, Laurie H.

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Dopamine Metabolism May Have Unexpected Benefits for Mitochondrial Energy Production von Sanders, Laurie H., Calakos, Nicole

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RAD52 is required for RNA-templated recombination repair in post-mitotic neurons von Welty, Starr, Teng, Yaqun, Liang, Zhuobin, Zhao, Weixing, Sanders, Laurie H., Greenamyre, J. Timothy, Rubio, Maria Eulalia, Thathiah, Amantha, Kodali, Ravindra, Wetzel, Ronald, Levine, Arthur S., Lan, Li

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Acoustofluidic multimodal diagnostic system for Alzheimer's disease von Hao, Nanjing, Wang, Zeyu, Liu, Pengzhan, Becker, Ryan, Yang, Shujie, Yang, Kaichun, Pei, Zhichao, Zhang, Peiran, Xia, Jianping, Shen, Liang, Wang, Lin, Welsh-Bohmer, Kathleen A., Sanders, Laurie H., Lee, Luke P., Huang, Tony Jun

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Inactive S. aureus Cas9 downregulates alpha-synuclein and reduces mtDNA damage and oxidative stress levels in human stem cell model of Parkinson’s disease von Sastre, Danuta, Zafar, Faria, Torres, C. Alejandra Morato, Piper, Desiree, Kirik, Deniz, Sanders, Laurie H., Qi, L. Stanley, Schüle, Birgitt

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Selective dopaminergic neurotoxicity modulated by inherent cell-type specific neurobiology von Currim, Fatema, Tanwar, Reeya, Brown-Leung, Josephine M., Paranjape, Neha, Liu, Jennifer, Sanders, Laurie H., Doorn, Jonathan A., Cannon, Jason R.

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Peripheral Klotho and Parkinson's Disease von Kakar, Rumit S., Pastor, Johanne V., Moe, Orson W., Ambrosio, Fabrisia, Castaldi, Danielle, Sanders, Laurie H.

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Single molecule array measures of LRRK2 kinase activity in serum link Parkinson's disease severity to peripheral inflammation von Yuan, Yuan, Li, Huizhong, Sreeram, Kashyap, Malankhanova, Tuyana, Boddu, Ravindra, Strader, Samuel, Chang, Allison, Bryant, Nicole, Yacoubian, Talene A, Standaert, David G, Erb, Madalynn, Moore, Darren J, Sanders, Laurie H, Lutz, Michael W, Velmeshev, Dmitry, West, Andrew B

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α-synucleinopathy exerts sex-dimorphic effects on the multipurpose DNA repair/redox protein APE1 in mice and humans von Miner, Kristin M., Jamenis, Anuj S., Bhatia, Tarun N., Clark, Rachel N., Rajasundaram, Dhivyaa, Sauvaigo, Sylvie, Mason, Daniel M., Posimo, Jessica M., Abraham, Nevil, DeMarco, Brett A., Hu, Xiaoming, Stetler, R. Anne, Chen, Jun, Sanders, Laurie H., Luk, Kelvin C., Leak, Rehana K.

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A Connection Between DNA Repair Protein APE1, Alpha‐Synucleinopathy, and Biological Sex in Rodents and Humans von Miner, Kristin M., Bhatia, Tarun N., Jamenis, Anuj S., Clark, Rachel N., Abraham, Nevil, Rajasundaram, Dhivyaa, Sauvaigo, Sylvie, Stetler, R. A., Chen, Jun, Sanders, Laurie H., Luk, Kelvin C., Leak, Rehana K.

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Fruit flies, bile acids, and Parkinson disease: a mitochondrial connection? von Greenamyre, J Timothy, Sanders, Laurie H, Gasser, Thomas

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G2019S selective LRRK2 kinase inhibitor abrogates mitochondrial DNA damage von Pena, Nicholas, Richbourg, Tara, Gonzalez-Hunt, Claudia P., Qi, Rui, Wren, Paul, Barlow, Carrolee, Shanks, Natalie F., Carlisle, Holly J., Sanders, Laurie H.

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GO system prevents ROS-induced mutagenesis and killing in Pseudomonas aeruginosa von Sanders, Laurie H, Sudhakaran, Julee, Sutton, Mark D

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Role of Pseudomonas aeruginosa dinB-Encoded DNA Polymerase IV in Mutagenesis von SANDERS, Laurie H, ROCKEL, Andrea, HAIPING LU, WOZNIAK, Daniel J, SUTTON, Mark D

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Regulation of complex I by Engrailed is complex too von Greenamyre, J Timothy, Sanders, Laurie H

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