Balancing repair and tolerance of DNA damage caused by alkylating agents von Fu, Dragony, Calvo, Jennifer A., Samson, Leona D.

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The Lancet Commission on pollution and health von Landrigan, Philip J, Fuller, Richard, Acosta, Nereus J R, Adeyi, Olusoji, Arnold, Robert, Basu, Niladri (Nil), Baldé, Abdoulaye Bibi, Bertollini, Roberto, Bose-O'Reilly, Stephan, Boufford, Jo Ivey, Breysse, Patrick N, Chiles, Thomas, Mahidol, Chulabhorn, Coll-Seck, Awa M, Cropper, Maureen L, Fobil, Julius, Fuster, Valentin, Greenstone, Michael, Haines, Andy, Hanrahan, David, Hunter, David, Khare, Mukesh, Krupnick, Alan, Lanphear, Bruce, Lohani, Bindu, Martin, Keith, Mathiasen, Karen V, McTeer, Maureen A, Murray, Christopher J L, Ndahimananjara, Johanita D, Perera, Frederica, Potočnik, Janez, Preker, Alexander S, Ramesh, Jairam, Rockström, Johan, Salinas, Carlos, Samson, Leona D, Sandilya, Karti, Sly, Peter D, Smith, Kirk R, Steiner, Achim, Stewart, Richard B, Suk, William A, van Schayck, Onno C P, Yadama, Gautam N, Yumkella, Kandeh, Zhong, Ma

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The human gut bacterial genotoxin colibactin alkylates DNA von Wilson, Matthew R., Jiang, Yindi, Villalta, Peter W., Stornetta, Alessia, Boudreau, Paul D., Carrá, Andrea, Brennan, Caitlin A., Chun, Eunyoung, Ngo, Lizzie, Samson, Leona D., Engelward, Bevin P., Garrett, Wendy S., Balbo, Silvia, Balskus, Emily P.

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ARID1A deficiency promotes mutability and potentiates therapeutic antitumor immunity unleashed by immune checkpoint blockade von Shen, Jianfeng, Ju, Zhenlin, Zhao, Wei, Wang, Lulu, Peng, Yang, Ge, Zhongqi, Nagel, Zachary D., Zou, Jun, Wang, Chen, Kapoor, Prabodh, Ma, Xiangyi, Ma, Ding, Liang, Jiyong, Song, Shumei, Liu, Jinsong, Samson, Leona D., Ajani, Jaffer A., Li, Guo-Min, Liang, Han, Shen, Xuetong, Mills, Gordon B., Peng, Guang

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H. John F. Cairns (1922–2018) von D Samson, Leona

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DNA Repair Capacity in Multiple Pathways Predicts Chemoresistance in Glioblastoma Multiforme von Nagel, Zachary D, Kitange, Gaspar J, Gupta, Shiv K, Joughin, Brian A, Chaim, Isaac A, Mazzucato, Patrizia, Lauffenburger, Douglas A, Sarkaria, Jann N, Samson, Leona D

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In vivo measurements of interindividual differences in DNA glycosylases and APE1 activities von Chaim, Isaac A., Nagel, Zachary D., Jordan, Jennifer J., Mazzucato, Patrizia, Ngo, Le P., Samson, Leona D.

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Multiplexed DNA repair assays for multiple lesions and multiple doses via transcription inhibition and transcriptional mutagenesis von Nagel, Zachary D., Margulies, Carrie M., Chaim, Isaac A., McRee, Siobhan K., Mazzucato, Patrizia, Ahmad, Anwaar, Abo, Ryan P., Butty, Vincent L., Forget, Anthony L., Samson, Leona D.

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CometChip analysis of human primary lymphocytes enables quantification of inter-individual differences in the kinetics of repair of oxidative DNA damage von Ngo, Le P., Kaushal, Simran, Chaim, Isaac A., Mazzucato, Patrizia, Ricciardi, Catherine, Samson, Leona D., Nagel, Zachary D., Engelward, Bevin P.

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Human ALKBH7 is required for alkylation and oxidation-induced programmed necrosis von Fu, Dragony, Jordan, Jennifer J, Samson, Leona D

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DNA damage induced by chronic inflammation contributes to colon carcinogenesis in mice von Meira, Lisiane B, Bugni, James M, Green, Stephanie L, Lee, Chung-Wei, Pang, Bo, Borenshtein, Diana, Rickman, Barry H, Rogers, Arlin B, Moroski-Erkul, Catherine A, McFaline, Jose L, Schauer, David B, Dedon, Peter C, Fox, James G, Samson, Leona D

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Systematic Discovery of In Vivo Phosphorylation Networks von Linding, Rune, Jensen, Lars Juhl, Ostheimer, Gerard J., van Vugt, Marcel A.T.M., Jørgensen, Claus, Miron, Ioana M., Diella, Francesca, Colwill, Karen, Taylor, Lorne, Elder, Kelly, Metalnikov, Pavel, Nguyen, Vivian, Pasculescu, Adrian, Jin, Jing, Park, Jin Gyoon, Samson, Leona D., Woodgett, James R., Russell, Robert B., Bork, Peer, Yaffe, Michael B., Pawson, Tony

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Fluorescent reporter assays provide direct, accurate, quantitative measurements of MGMT status in human cells von Nagel, Zachary D, Beharry, Andrew A, Mazzucato, Patrizia, Kitange, Gaspar J, Sarkaria, Jann N, Kool, Eric T, Samson, Leona D

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Exposure to arsenic in utero is associated with various types of DNA damage and micronuclei in newborns: a birth cohort study von Navasumrit, Panida, Chaisatra, Krittinee, Promvijit, Jeerawan, Parnlob, Varabhorn, Waraprasit, Somchamai, Chompoobut, Chalida, Binh, Ta Thi, Hai, Doan Ngoc, Bao, Nguyen Duy, Hai, Nguyen Khac, Kim, Kyoung-Woong, Samson, Leona D, Graziano, Joseph H, Mahidol, Chulabhorn, Ruchirawat, Mathuros

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Human AlkB Homolog ABH8 Is a tRNA Methyltransferase Required for Wobble Uridine Modification and DNA Damage Survival von Fu, Dragony, Brophy, Jennifer A. N., Chan, Clement T. Y., Atmore, Kyle A., Begley, Ulrike, Paules, Richard S., Dedon, Peter C., Begley, Thomas J., Samson, Leona D.

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Alkyladenine DNA glycosylase associates with transcription elongation to coordinate DNA repair with gene expression von Montaldo, Nicola P., Bordin, Diana L., Brambilla, Alessandro, Rösinger, Marcel, Fordyce Martin, Sarah L., Bjørås, Karine Øian, Bradamante, Stefano, Aas, Per Arne, Furrer, Antonia, Olsen, Lene C., Kunath, Nicolas, Otterlei, Marit, Sætrom, Pål, Bjørås, Magnar, Samson, Leona D., van Loon, Barbara

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Fluorogenic Real-Time Reporters of DNA Repair by MGMT, a Clinical Predictor of Antitumor Drug Response von Beharry, Andrew A, Nagel, Zachary D, Samson, Leona D, Kool, Eric T

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Alkylation induced cerebellar degeneration dependent on Aag and Parp1 does not occur via previously established cell death mechanisms von Margulies, Carrie M, Chaim, Isaac Alexander, Mazumder, Aprotim, Criscione, June, Samson, Leona D

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Aag-initiated base excision repair promotes ischemia reperfusion injury in liver, brain, and kidney von Ebrahimkhani, Mohammad R, Daneshmand, Ali, Mazumder, Aprotim, Allocca, Mariacarmela, Calvo, Jennifer A, Abolhassani, Nona, Jhun, Iny, Muthupalani, Sureshkumar, Ayata, Cenk, Samson, Leona D

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Microcolony Size Distribution Assay Enables High-Throughput Cell Survival Quantitation von Ngo, Le P., Chan, Tze Khee, Ge, Jing, Samson, Leona D., Engelward, Bevin P.

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