Morphinan Evolution: The Impact of Advances in Biochemistry and Molecular Biology von Kajino, Keita, Tokuda, Akihisa, Saitoh, Tsuyoshi

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Nonpeptide orexin type-2 receptor agonist ameliorates narcolepsy-cataplexy symptoms in mouse models von Irukayama-Tomobe, Yoko, Ogawa, Yasuhiro, Tominaga, Hiromu, Ishikawa, Yukiko, Hosokawa, Naoto, Ambai, Shinobu, Kawabe, Yuki, Uchida, Shuntaro, Nakajima, Ryo, Saitoh, Tsuyoshi, Kanda, Takeshi, Vogt, Kaspar, Sakurai, Takeshi, Nagase, Hiroshi, Yanagisawa, Masashi

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Anodic Oxidation of Phenols: A Key Step for the Synthesis of Natural Products von Yamamoto, Takashi, Saitoh, Tsuyoshi, Einaga, Yasuaki, Nishiyama, Shigeru

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Controlled decoration of boron-doped diamond electrodes by electrochemical click reaction (e−CLICK) von Yamamoto, Takashi, Akahori, Miku, Natsui, Keisuke, Saitoh, Tsuyoshi, Einaga, Yasuaki

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Visceral Fat Area by Abdominal Bioelectrical Impedance Analysis as a Risk of Obstructive Sleep Apnea: A Single-Clinic Retrospective Case Study von Sekizuka, Hiromitsu, Ono, Yoshiaki, Saitoh, Tsuyoshi, Ono, Yoshitaka

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OX2R-selective orexin agonism is sufficient to ameliorate cataplexy and sleep/wake fragmentation without inducing drug-seeking behavior in mouse model of narcolepsy von Yamamoto, Hikari, Nagumo, Yasuyuki, Ishikawa, Yukiko, Irukayama-Tomobe, Yoko, Namekawa, Yukiko, Nemoto, Tsuyoshi, Tanaka, Hiromu, Takahashi, Genki, Tokuda, Akihisa, Saitoh, Tsuyoshi, Nagase, Hiroshi, Funato, Hiromasa, Yanagisawa, Masashi

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A solvent-directed stereoselective and electrocatalytic synthesis of diisoeugenol von Yamamoto, Takashi, Riehl, Barbara, Naba, Keisuke, Nakahara, Kenshin, Wiebe, Anton, Saitoh, Tsuyoshi, Waldvogel, Siegfried R, Einaga, Yasuaki

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Design and Synthesis of Non-Peptide, Selective Orexin Receptor 2 Agonists von Nagahara, Takashi, Saitoh, Tsuyoshi, Kutsumura, Noriki, Irukayama-Tomobe, Yoko, Ogawa, Yasuhiro, Kuroda, Daisuke, Gouda, Hiroaki, Kumagai, Hidetoshi, Fujii, Hideaki, Yanagisawa, Masashi, Nagase, Hiroshi

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Anodic Oxidation on a Boron-Doped Diamond Electrode Mediated by Methoxy Radicals von Sumi, Takenori, Saitoh, Tsuyoshi, Natsui, Keisuke, Yamamoto, Takashi, Atobe, Mahito, Einaga, Yasuaki, Nishiyama, Shigeru

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Topical administration of the kappa opioid receptor agonist nalfurafine suppresses corneal neovascularization and inflammation von Shokirova, Hurramhon, Inomata, Takenori, Saitoh, Tsuyoshi, Zhu, Jun, Fujio, Kenta, Okumura, Yuichi, Yanagawa, Ai, Fujimoto, Keiichi, Sung, Jaemyoung, Eguchi, Atsuko, Miura, Maria, Nagino, Ken, Hirosawa, Kunihiko, Kuwahara, Mizu, Akasaki, Yasutsugu, Nagase, Hiroshi, Murakami, Akira

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Electro-conversion of cumene into acetophenone using boron-doped diamond electrodes von Kitano, Mana, Saitoh, Tsuyoshi, Nishiyama, Shigeru, Einaga, Yasuaki, Yamamoto, Takashi

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Design and Synthesis of Orexin 1 Receptor-Selective Agonists von Iio, Keita, Hashimoto, Kao, Nagumo, Yasuyuki, Amezawa, Mao, Hasegawa, Taisei, Yamamoto, Naoshi, Kutsumura, Noriki, Takeuchi, Katsuhiko, Ishikawa, Yukiko, Yamamoto, Hikari, Tokuda, Akihisa, Sato, Tetsu, Uchida, Yasuo, Inoue, Asuka, Tanimura, Ryuji, Yanagisawa, Masashi, Nagase, Hiroshi, Saitoh, Tsuyoshi

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Discovery of orexin 2 receptor selective and dual orexin receptor agonists based on the tetralin structure: Switching of receptor selectivity by chirality on the tetralin ring von Iio, Keita, Saitoh, Tsuyoshi, Ohshita, Ryuichiro, Hino, Tsubasa, Amezawa, Mao, Takayama, Yoshiaki, Nagumo, Yasuyuki, Yamamoto, Naoshi, Kutsumura, Noriki, Irukayama-Tomobe, Yoko, Ishikawa, Yukiko, Tanimura, Ryuji, Yanagisawa, Masashi, Nagase, Hiroshi

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Design and synthesis of novel orexin 2 receptor agonists based on naphthalene skeleton von Hino, Tsubasa, Saitoh, Tsuyoshi, Nagumo, Yasuyuki, Yamamoto, Naoshi, Kutsumura, Noriki, Irukayama-Tomobe, Yoko, Ishikawa, Yukiko, Tanimura, Ryuji, Yanagisawa, Masashi, Nagase, Hiroshi

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Large-scale forward genetics screening identifies Trpa1 as a chemosensor for predator odor-evoked innate fear behaviors von Wang, Yibing, Cao, Liqin, Lee, Chia-Ying, Matsuo, Tomohiko, Wu, Kejia, Asher, Greg, Tang, Lijun, Saitoh, Tsuyoshi, Russell, Jamie, Klewe-Nebenius, Daniela, Wang, Li, Soya, Shingo, Hasegawa, Emi, Chérasse, Yoan, Zhou, Jiamin, Li, Yuwenbin, Wang, Tao, Zhan, Xiaowei, Miyoshi, Chika, Irukayama, Yoko, Cao, Jie, Meeks, Julian P., Gautron, Laurent, Wang, Zhiqiang, Sakurai, Katsuyasu, Funato, Hiromasa, Sakurai, Takeshi, Yanagisawa, Masashi, Nagase, Hiroshi, Kobayakawa, Reiko, Kobayakawa, Ko, Beutler, Bruce, Liu, Qinghua

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Nonpeptide Orexin-2 Receptor Agonist Attenuates Morphine-induced Sedative Effects in Rats von Toyama, Satoshi, Shimoyama, Naohito, Tagaito, Yugo, Nagase, Hiroshi, Saitoh, Tsuyoshi, Yanagisawa, Masashi, Shimoyama, Megumi

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Optochemical control of slow-wave sleep in the nucleus accumbens of male mice by a photoactivatable allosteric modulator of adenosine A2A receptors von Roy, Koustav, Zhou, Xuzhao, Otani, Rintaro, Yuan, Ping-Chuan, Ioka, Shuji, Vogt, Kaspar E., Kondo, Tamae, Farag, Nouran H. T., Ijiri, Haruto, Wu, Zhaofa, Chitose, Youhei, Amezawa, Mao, Uygun, David S., Cherasse, Yoan, Nagase, Hiroshi, Li, Yulong, Yanagisawa, Masashi, Abe, Manabu, Basheer, Radhika, Wang, Yi-Qun, Saitoh, Tsuyoshi, Lazarus, Michael

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Essential structure of orexin 1 receptor antagonist YNT-707: Conversion of the 16-cyclopropylmethyl group to the 16-sulfonamide group in d-nor-nalfurafine derivatives von Katoh, Koki, Kutsumura, Noriki, Yamamoto, Naoshi, Nagumo, Yasuyuki, Saitoh, Tsuyoshi, Ishikawa, Yukiko, Irukayama-Tomobe, Yoko, Tanimura, Ryuji, Yanagisawa, Masashi, Nagase, Hiroshi

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Synthesis of unnatural morphinan compounds to induce itch-like behaviors in mice: Towards the development of MRGPRX2 selective ligands von Iio, Keita, Kutsumura, Noriki, Nagumo, Yasuyuki, Saitoh, Tsuyoshi, Tokuda, Akihisa, Hashimoto, Kao, Yamamoto, Naoshi, Kise, Ryoji, Inoue, Asuka, Mizoguchi, Hirokazu, Nagase, Hiroshi

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Effect of removal of the 14-hydroxy group on the affinity of the 4,5-epoxymorphinan derivatives for orexin and opioid receptors von Katoh, Koki, Yamamoto, Naoshi, Ishikawa, Yukiko, Irukayama-Tomobe, Yoko, Tanimura, Ryuji, Saitoh, Tsuyoshi, Nagumo, Yasuyuki, Kutsumura, Noriki, Yanagisawa, Masashi, Nagase, Hiroshi

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