Regulation of the anti-tumour immune response by cancer-associated fibroblasts von Harper, James, Sainson, Richard C.A

Volltext

Delta-like 4 Notch Ligand Regulates Tumor Angiogenesis, Improves Tumor Vascular Function, and Promotes Tumor Growth In vivo von LI, Ji-Liang, SAINSON, Richard C. A, HARRIS, Adrian L, WEN SHI, LEEK, Russell, HARRINGTON, Laura S, PREUSSER, Matthias, BISWAS, Swethajit, TURLEY, Helen, HEIKAMP, Emily, HAINFELLNER, Johannes A

Volltext

DLL4-Notch Signaling Mediates Tumor Resistance to Anti-VEGF Therapy In Vivo von LI, Ji-Liang, SAINSON, Richard C. A, WU, Herren, CHOWDHURY, Partha S, RUSSELL, Angela J, MONTGOMERY, Craig P, POULSOM, Richard, HARRIS, Adrian L, EIN OON, Chern, TURLEY, Helen, LEEK, Russell, SHELDON, Helen, BRIDGES, Esther, SHI, Wen, SNELL, Cameron, BOWDEN, Emma T

Volltext

New mechanism for Notch signaling to endothelium at a distance by Delta-like 4 incorporation into exosomes von Sheldon, Helen, Heikamp, Emily, Turley, Helen, Dragovic, Rebecca, Thomas, Peter, Oon, Chern Ein, Leek, Russell, Edelmann, Mariola, Kessler, Benedikt, Sainson, Richard C.A., Sargent, Ian, Li, Ji-Liang, Harris, Adrian L.

Volltext

A Conserved Mechanism for Steroid Receptor Translocation to the Plasma Membrane von Pedram, Ali, Razandi, Mahnaz, Sainson, Richard C.A., Kim, Jin K., Hughes, Christopher C., Levin, Ellis R.

Volltext

Rational Selection of Syngeneic Preclinical Tumor Models for Immunotherapeutic Drug Discovery von Mosely, Suzanne I S, Prime, John E, Sainson, Richard C A, Koopmann, Jens-Oliver, Wang, Dennis Y Q, Greenawalt, Danielle M, Ahdesmaki, Miika J, Leyland, Rebecca, Mullins, Stefanie, Pacelli, Luciano, Marcus, Danielle, Anderton, Judith, Watkins, Amanda, Coates Ulrichsen, Jane, Brohawn, Philip, Higgs, Brandon W, McCourt, Matthew, Jones, Hazel, Harper, James A, Morrow, Michelle, Valge-Archer, Viia, Stewart, Ross, Dovedi, Simon J, Wilkinson, Robert W

Volltext

TNF primes endothelial cells for angiogenic sprouting by inducing a tip cell phenotype von Sainson, Richard C.A., Johnston, Douglas A., Chu, Henry C., Holderfield, Matthew T., Nakatsu, Martin N., Crampton, Steven P., Davis, Jaeger, Conn, Erin, Hughes, Christopher C.W.

Volltext

Downregulation of Manic fringe impedes angiogenesis and cell migration of renal carcinoma von Cheng, Wei Kang, Oon, Chern Ein, Kaur, Gurjeet, Sainson, Richard C.A., Li, Ji-Liang

Volltext

ICOS-Positive Regulatory T Cells in Hepatocellular Carcinoma: The Perspective from Digital Pathology Analysis von Lu, Li-Chun, Deantonio, Cecilia, Palu, Cintia C., Lee, Yi-Hsuan, Mitchell, Laura S., Cowan, Marianne, Corser, Matthew, Sherry, Lorcan, Cheng, Ann-Lii, Quaratino, Sonia, Shao, Yu-Yun, Sainson, Richard C.A., Hsu, Chih-Hung

Volltext

Optoacoustic Detection of Early Therapy-Induced Tumor Cell Death Using a Targeted Imaging Agent von Xie, Bangwen, Tomaszewski, Michal R, Neves, André A, Ros, Susana, Hu, De-En, McGuire, Sarah, Mullins, Stefanie R, Tice, David, Sainson, Richard C A, Bohndiek, Sarah E, Wilkinson, Robert W, Brindle, Kevin M

Volltext

Cell-autonomous notch signaling regulates endothelial cell branching and proliferation during vascular tubulogenesis von Sainson, Richard C. A, Aoto, Jason, Nakatsu, Martin N, Holderfield, Matthew, Conn, Erin, Koller, Erich, Hughes, Christopher C. W

Volltext

A Phase 1 First-in-Human Study of FS118, a Tetravalent Bispecific Antibody Targeting LAG-3 and PD-L1 in Patients with Advanced Cancer and PD-L1 Resistance von Yap, Timothy A, LoRusso, Patricia M, Wong, Deborah J, Hu-Lieskovan, Siwen, Papadopoulos, Kyriakos P, Holz, Josefin-Beate, Grabowska, Urszula, Gradinaru, Cristian, Leung, Kin-Mei, Marshall, Sylwia, Reader, Claire S, Russell, Roslin, Sainson, Richard C A, Seal, Claire J, Shepherd, Christopher J, Germaschewski, Fiona, Gliddon, Daniel, Stern, Omer, Young, Lesley, Brewis, Neil, Kayitalire, Louis, Morrow, Michelle

Volltext

Regulation of angiogenesis by homotypic and heterotypic notch signalling in endothelial cells and pericytes: from basic research to potential therapies von Sainson, Richard C. A., Harris, Adrian L.

Volltext

Regulation of CXCR4 by the Notch Ligand Delta-like 4 in Endothelial Cells von WILLIAMS, Cassin Kimmel, SEGARRA, Marta, DE LA LUZ SIERRA, Maria, SAINSON, Richard C. A, TOSATO, Giovanna, HARRIS, Adrian L

Volltext

Role of Delta-like 4 in Jagged1-induced tumour angiogenesis and tumour growth von Oon, Chern Ein, Bridges, Esther, Sheldon, Helen, Sainson, Richard C A, Jubb, Adrian, Turley, Helen, Leek, Russell, Buffa, Francesca, Harris, Adrian L, Li, Ji-Liang

Volltext

Anti-Dll4 therapy: can we block tumour growth by increasing angiogenesis? von Sainson, Richard C.A, Harris, Adrian L

Volltext

Angiogenic sprouting and capillary lumen formation modeled by human umbilical vein endothelial cells (HUVEC) in fibrin gels: the role of fibroblasts and Angiopoietin-1 von Nakatsu, Martin N., Sainson, Richard C.A., Aoto, Jason N., Taylor, Kevin L., Aitkenhead, Mark, Pérez-del-Pulgar, Sofía, Carpenter, Philip M., Hughes, Christopher C.W.

Volltext

Characterization and application of two RANK-specific antibodies with different biological activities von Chypre, Mélanie, Seaman, Jonathan, Cordeiro, Olga G, Willen, Laure, Knoop, Kathryn A, Buchanan, Andrew, Sainson, Richard C.A, Williams, Ifor R, Yagita, Hideo, Schneider, Pascal, Mueller, Christopher G

Volltext

An Antibody Targeting ICOS Increases Intratumoral Cytotoxic to Regulatory T-cell Ratio and Induces Tumor Regression von Sainson, Richard C A, Thotakura, Anil K, Kosmac, Miha, Borhis, Gwenoline, Parveen, Nahida, Kimber, Rachael, Carvalho, Joana, Henderson, Simon J, Pryke, Kerstin L, Okell, Tracey, O'Leary, Siobhan, Ball, Stuart, Van Krinks, Cassie, Gamand, Lauriane, Taggart, Emma, Pring, Eleanor J, Ali, Hanif, Craig, Hannah, Wong, Vivian W Y, Liang, Qi, Rowlands, Robert J, Lecointre, Morgane, Campbell, Jamie, Kirby, Ian, Melvin, David, Germaschewski, Volker, Oelmann, Elisabeth, Quaratino, Sonia, McCourt, Matthew

Volltext

Regulation of multiple angiogenic pathways by Dll4 and Notch in human umbilical vein endothelial cells von Harrington, Laura S., Sainson, Richard C.A., Williams, Cassin Kimmel, Taylor, Jennifer M., Shi, Wen, Li, Ji-Liang, Harris, Adrian L.

Volltext