Symbiotic polyamine metabolism regulates epithelial proliferation and macrophage differentiation in the colon von Nakamura, Atsuo, Kurihara, Shin, Takahashi, Daisuke, Ohashi, Wakana, Nakamura, Yutaka, Kimura, Shunsuke, Onuki, Masayoshi, Kume, Aiko, Sasazawa, Yukiko, Furusawa, Yukihiro, Obata, Yuuki, Fukuda, Shinji, Saiki, Shinji, Matsumoto, Mitsuharu, Hase, Koji

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Identification of novel biomarkers for Parkinson's disease by metabolomic technologies von Hatano, Taku, Saiki, Shinji, Okuzumi, Ayami, Mohney, Robert P, Hattori, Nobutaka

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Iron Supply via NCOA4-Mediated Ferritin Degradation Maintains Mitochondrial Functions von Fujimaki, Motoki, Furuya, Norihiko, Saiki, Shinji, Amo, Taku, Imamichi, Yoko, Hattori, Nobutaka

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Metabolomic analysis revealed mitochondrial dysfunction and aberrant choline metabolism in MPP+-exposed SH-SY5Y cells von Amo, Taku, Oji, Yutaka, Saiki, Shinji, Hattori, Nobutaka

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PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy von Matsuda, Noriyuki, Sato, Shigeto, Shiba, Kahori, Okatsu, Kei, Saisho, Keiko, Gautier, Clement A, Sou, Yu-shin, Saiki, Shinji, Kawajiri, Sumihiro, Sato, Fumiaki, Kimura, Mayumi, Komatsu, Masaaki, Hattori, Nobutaka, Tanaka, Keiji

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Loss of autophagy in dopaminergic neurons causes Lewy pathology and motor dysfunction in aged mice von Sato, Shigeto, Uchihara, Toshiki, Fukuda, Takahiro, Noda, Sachiko, Kondo, Hiromi, Saiki, Shinji, Komatsu, Masaaki, Uchiyama, Yasuo, Tanaka, Keiji, Hattori, Nobutaka

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CHCHD2 mutations in autosomal dominant late-onset Parkinson's disease: a genome-wide linkage and sequencing study von Funayama, Manabu, PhD, Ohe, Kenji, MD, Amo, Taku, PhD, Furuya, Norihiko, PhD, Yamaguchi, Junji, MSc, Saiki, Shinji, MD, Li, Yuanzhe, MD, Ogaki, Kotaro, MD, Ando, Maya, MD, Yoshino, Hiroyo, PhD, Tomiyama, Hiroyuki, MD, Nishioka, Kenya, MD, Hasegawa, Kazuko, MD, Saiki, Hidemoto, MD, Satake, Wataru, MD, Mogushi, Kaoru, PhD, Sasaki, Ryogen, MD, Kokubo, Yasumasa, Prof, Kuzuhara, Shigeki, Prof, Toda, Tatsushi, Prof, Mizuno, Yoshikuni, Prof, Uchiyama, Yasuo, Prof, Ohno, Kinji, Prof, Hattori, Nobutaka, Prof

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Non-invasive diagnostic tool for Parkinson’s disease by sebum RNA profile with machine learning von Uehara, Yuya, Ueno, Shin-Ichi, Amano-Takeshige, Haruka, Suzuki, Shuji, Imamichi, Yoko, Fujimaki, Motoki, Ota, Noriyasu, Murase, Takatoshi, Inoue, Takayoshi, Saiki, Shinji, Hattori, Nobutaka

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Randomized double-blind placebo-controlled trial of hydrogen inhalation for Parkinson’s disease: a pilot study von Yoritaka, Asako, Kobayashi, Yasuko, Hayashi, Tetsuo, Saiki, Shinji, Hattori, Nobutaka

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Soluble epoxide hydrolase plays a key role in the pathogenesis of Parkinson’s disease von Ren, Qian, Ma, Min, Yang, Jun, Nonaka, Risa, Yamaguchi, Akihiro, Ishikawa, Kei-ichi, Kobayashi, Kenta, Murayama, Shigeo, Hwang, Sung Hee, Saiki, Shinji, Akamatsu, Wado, Hattori, Nobutaka, Hammock, Bruce D., Hashimoto, Kenji

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Intrajejunal Infusion of Levodopa/Carbidopa for Advanced Parkinson's Disease: A Systematic Review von Tsunemi, Taiji, Oyama, Genko, Saiki, Shinji, Hatano, Taku, Fukae, Jiro, Shimo, Yasushi, Hattori, Nobutaka

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Lysosomal positioning coordinates cellular nutrient responses von Siddiqi, Farah H, Roberts, Esteban A, Rubinsztein, David C, Menzies, Fiona M, Sarkar, Sovan, Imarisio, Sara, O'Kane, Cahir J, Futter, Marie, Deretic, Vojo, Saiki, Shinji, Jahreiss, Luca, Korolchuk, Viktor I, Lichtenberg, Maike

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A metabolic profile of polyamines in parkinson disease: A promising biomarker von Saiki, Shinji, Sasazawa, Yukiko, Fujimaki, Motoki, Kamagata, Koji, Kaga, Naoko, Taka, Hikari, Li, Yuanzhe, Souma, Sanae, Hatano, Taku, Imamichi, Yoko, Furuya, Norihiko, Mori, Akio, Oji, Yutaka, Ueno, Shin‐Ichi, Nojiri, Shuko, Miura, Yoshiki, Ueno, Takashi, Funayama, Manabu, Aoki, Shigeki, Hattori, Nobutaka

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Novel autophagy inducers by accelerating lysosomal clustering against Parkinson's disease von Date, Yuki, Sasazawa, Yukiko, Kitagawa, Mitsuhiro, Gejima, Kentaro, Suzuki, Ayami, Saya, Hideyuki, Kida, Yasuyuki, Imoto, Masaya, Itakura, Eisuke, Hattori, Nobutaka, Saiki, Shinji

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Caffeine induces apoptosis by enhancement of autophagy via PI3K/Akt/mTOR/p70S6K inhibition von Saiki, Shinji, Sasazawa, Yukiko, Imamichi, Yoko, Kawajiri, Sumihiro, Fujimaki, Takahiro, Tanida, Isei, Kobayashi, Hiroki, Sato, Fumiaki, Sato, Shigeto, Ishikawa, Ken-Ichi, Imoto, Masaya, Hattori, Nobutaka

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Decreased long-chain acylcarnitines from insufficient β-oxidation as potential early diagnostic markers for Parkinson’s disease von Saiki, Shinji, Hatano, Taku, Fujimaki, Motoki, Ishikawa, Kei-Ichi, Mori, Akio, Oji, Yutaka, Okuzumi, Ayami, Fukuhara, Takeshi, Koinuma, Takahiro, Imamichi, Yoko, Nagumo, Miho, Furuya, Norihiko, Nojiri, Shuko, Amo, Taku, Yamashiro, Kazuo, Hattori, Nobutaka

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A rational mechanism for combination treatment of Huntington's disease using lithium and rapamycin von Sarkar, Sovan, Krishna, Gauri, Imarisio, Sara, Saiki, Shinji, O'Kane, Cahir J., Rubinsztein, David C.

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Neuroprotective effects of memantine via enhancement of autophagy von Hirano, Kazuoki, Fujimaki, Motoki, Sasazawa, Yukiko, Yamaguchi, Akihiro, Ishikawa, Kei-Ichi, Miyamoto, Kengo, Souma, Sanae, Furuya, Norihiko, Imamichi, Yoko, Yamada, Daisuke, Saya, Hideyuki, Akamatsu, Wado, Saiki, Shinji, Hattori, Nobutaka

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BRUP‐1, an intracellular bilirubin modulator, exerts neuroprotective activity in a cellular Parkinson’s disease model von Kataura, Tetsushi, Saiki, Shinji, Ishikawa, Kei‐ichi, Akamatsu, Wado, Sasazawa, Yukiko, Hattori, Nobutaka, Imoto, Masaya

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Targeting the autophagy-NAD axis protects against cell death in Niemann-Pick type C1 disease models von Kataura, Tetsushi, Sedlackova, Lucia, Sun, Congxin, Kocak, Gamze, Wilson, Niall, Banks, Peter, Hayat, Faisal, Trushin, Sergey, Trushina, Eugenia, Maddocks, Oliver D. K., Oblong, John E., Miwa, Satomi, Imoto, Masaya, Saiki, Shinji, Erskine, Daniel, Migaud, Marie E., Sarkar, Sovan, Korolchuk, Viktor I.

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