Immune Checkpoint inhibitors: An introduction to the next-generation cancer immunotherapy von Lee, Lucy, Gupta, Manish, Sahasranaman, Srikumar

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Targeting TIGIT for Immunotherapy of Cancer: Update on Clinical Development von Rotte, Anand, Sahasranaman, Srikumar, Budha, Nageshwar

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Clinical pharmacology and pharmacogenetics of thiopurines von Sahasranaman, Srikumar, Howard, Danny, Roy, Sandip

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Effect of rifampin and itraconazole on the pharmacokinetics of zanubrutinib (a Bruton's tyrosine kinase inhibitor) in Asian and non-Asian healthy subjects von Mu, Song, Tang, Zhiyu, Novotny, William, Tawashi, Manal, Li, Ta-Kai, Ou, Ying, Sahasranaman, Srikumar

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The pharmacokinetics of pamiparib in the presence of a strong CYP3A inhibitor (itraconazole) and strong CYP3A inducer (rifampin) in patients with solid tumors: an open-label, paral... von Mu, Song, Lin, Chester, Skrzypczyk-Ostaszewicz, Anna, Bulat, Iurie, Maglakelidze, Marina, Skarbova, Viera, Andreu-Vieyra, Claudia, Sahasranaman, Srikumar

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Phase I Study of GDC-0425, a Checkpoint Kinase 1 Inhibitor, in Combination with Gemcitabine in Patients with Refractory Solid Tumors von Infante, Jeffrey R, Hollebecque, Antoine, Postel-Vinay, Sophie, Bauer, Todd M, Blackwood, Elizabeth M, Evangelista, Marie, Mahrus, Sami, Peale, Franklin V, Lu, Xuyang, Sahasranaman, Srikumar, Zhu, Rui, Chen, Yuan, Ding, Xiao, Murray, Elaine R, Schutzman, Jennifer L, Lauchle, Jennifer O, Soria, Jean-Charles, LoRusso, Patricia M

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Effect of OATP1B1/1B3 Inhibitor GDC‐0810 on the Pharmacokinetics of Pravastatin and Coproporphyrin I/III in Healthy Female Subjects von Liu, Lichuan, Cheeti, Sravanthi, Yoshida, Kenta, Choo, Edna, Chen, Eugene, Chen, Buyun, Gates, Mary, Singel, Stina, Morley, Roland, Ware, Joseph, Sahasranaman, Srikumar

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Population Pharmacokinetic Analysis of the BTK Inhibitor Zanubrutinib in Healthy Volunteers and Patients With B‐Cell Malignancies von Ou, Ying C., Liu, Lucy, Tariq, Bilal, Wang, Kun, Jindal, Ashutosh, Tang, Zhiyu, Gao, Yuying, Sahasranaman, Srikumar

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Comprehensive PBPK model to predict drug interaction potential of Zanubrutinib as a victim or perpetrator von Wang, Kun, Yao, Xueting, Zhang, Miao, Liu, Dongyang, Gao, Yuying, Sahasranaman, Srikumar, Ou, Ying C.

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Evaluation of HDL-modulating interventions for cardiovascular risk reduction using a systems pharmacology approach von Gadkar, Kapil, Lu, James, Sahasranaman, Srikumar, Davis, John, Mazer, Norman A., Ramanujan, Saroja

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Clinical dose rationale of tislelizumab in patients with solid or hematological advanced tumors von Yu, Tian, Liu, Xiangyu, Wu, Chi‐Yuan, Tang, Zhiyu, Wang, Hongwei, Schnell, Patrick, Wan, Ya, Wang, Kun, Liu, Lucy, Gao, Yuying, Sahasranaman, Srikumar, Budha, Nageshwar

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Model‐based population pharmacokinetic analysis of tislelizumab in patients with advanced tumors von Budha, Nageshwar, Wu, Chi‐Yuan, Tang, Zhiyu, Yu, Tian, Liu, Lucy, Xu, Fengyan, Gao, Yuying, Li, Ruiying, Zhang, Qiuyang, Wan, Ya, Sahasranaman, Srikumar

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In vitro investigations into the roles of CYP450 enzymes and drug transporters in the drug interactions of zanubrutinib, a covalent Bruton's tyrosine kinase inhibitor von Zhang, Heather, Ou, Ying C., Su, Dan, Wang, Fan, Wang, Lai, Sahasranaman, Srikumar, Tang, Zhiyu

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Validation of a method for the determination of thiocyanate in human plasma by UV/VIS spectrophotometry and application to a Phase I clinical trial of GDC-0425 von Shin, Young G., Meijering, Henri, van Heuveln, Fred H., Wieling, Jaap, Halladay, Jason, Sahasranaman, Srikumar, Hop, Cornelis E.C.A.

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GDC-0810 Pharmacokinetics and Transporter-Mediated Drug Interaction Evaluation with an Endogenous Biomarker in the First-in-Human, Dose Escalation Study von Cheung, Kit Wun Kathy, Yoshida, Kenta, Cheeti, Sravanthi, Chen, Buyun, Morley, Roland, Chan, Iris T, Sahasranaman, Srikumar, Liu, Lichuan

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Use of in vitro critical inhibitory concentration, a novel approach to predict in vivo synergistic bactericidal effect of combined amikacin and piperacillin against Pseudomonas aer... von CHAN, Eli, SHUFENG ZHOU, SRIKUMAR, Sahasranaman, WEI DUAN

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Absorption, Metabolism, and Excretion of Taselisib (GDC-0032), a Potent β -Sparing PI3K Inhibitor in Rats, Dogs, and Humans von Ma, Shuguang, Cho, Sungjoon, Sahasranaman, Srikumar, Zhao, Weiping, Pang, Jodie, Ding, Xiao, Dean, Brian, Wang, Bin, Hsu, Jerry Y, Ware, Joseph, Salphati, Laurent

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A sensitive liquid chromatography-tandem mass spectrometry method for the quantification of mometasone furoate in human plasma von SAHASRANAMAN, Srikumar, YUFEI TANG, BINIASZ, Diana, HOCHHAUS, Guenther

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A Quantitative Systems Pharmacology (QSP) Model to Predict Receptor Occupancy of Bruton's Tyrosine Kinase (BTK) Inhibitors in Peripheral Blood Mononuclear Cells, Bone Marrow and Ly... von Sahasranaman, Srikumar, Demin, Oleg, Shchelokov, Dmitry, Musatova, Veronika, Budha, Nageshwar, Ou, Ying

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Evaluation of drug interaction potential of zanubrutinib with cocktail probes representative of CYP3A4, CYP2C9, CYP2C19, P‐gp and BCRP von Ou, Ying C., Tang, Zhiyu, Novotny, William, Tawashi, Manal, Li, Ta‐Kai, Coleman, Hugh A., Sahasranaman, Srikumar

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