Sporadic human prion diseases: molecular insights and diagnosis von Puoti, Gianfranco, MD, Bizzi, Alberto, MD, Forloni, Gianluigi, PhD, Safar, Jiri G, MD, Tagliavini, Fabrizio, MD, Gambetti, Pierluigi, Prof

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Diagnostic and prognostic value of human prion detection in cerebrospinal fluid von Foutz, Aaron, Appleby, Brian S., Hamlin, Clive, Liu, Xiaoqin, Yang, Sheng, Cohen, Yvonne, Chen, Wei, Blevins, Janis, Fausett, Cameron, Wang, Han, Gambetti, Pierluigi, Zhang, Shulin, Hughson, Andrew, Tatsuoka, Curtis, Schonberger, Lawrence B., Cohen, Mark L., Caughey, Byron, Safar, Jiri G.

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Proteomic differences in amyloid plaques in rapidly progressive and sporadic Alzheimer’s disease von Drummond, Eleanor, Nayak, Shruti, Faustin, Arline, Pires, Geoffrey, Hickman, Richard A., Askenazi, Manor, Cohen, Mark, Haldiman, Tracy, Kim, Chae, Han, Xiaoxia, Shao, Yongzhao, Safar, Jiri G., Ueberheide, Beatrix, Wisniewski, Thomas

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Protease-sensitive conformers in broad spectrum of distinct PrPSc structures in sporadic Creutzfeldt-Jakob disease are indicator of progression rate von Kim, Chae, Haldiman, Tracy, Cohen, Yvonne, Chen, Wei, Blevins, Janis, Sy, Man-Sun, Cohen, Mark, Safar, Jiri G

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Distinct prion-like strains of amyloid beta implicated in phenotypic diversity of Alzheimer's disease von Cohen, Mark, Appleby, Brian, Safar, Jiri G.

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Chronic wasting disease (CWD) prion strains evolve via adaptive diversification of conformers in hosts expressing prion protein polymorphisms von Duque Velásquez, Camilo, Kim, Chae, Haldiman, Tracy, Kim, Chiye, Herbst, Allen, Aiken, Judd, Safar, Jiri G., McKenzie, Debbie

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Structural determinants of phenotypic diversity and replication rate of human prions von Safar, Jiri G, Xiao, Xiangzhu, Kabir, Mohammad E, Chen, Shugui, Kim, Chae, Haldiman, Tracy, Cohen, Yvonne, Chen, Wei, Cohen, Mark L, Surewicz, Witold K

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A Role of Low-Density Lipoprotein Receptor-Related Protein 4 (LRP4) in Astrocytic Aβ Clearance von Zhang, Hongsheng, Chen, Wenbing, Tan, Zhibing, Zhang, Lei, Dong, Zhaoqi, Cui, Wanpeng, Zhao, Kai, Wang, Hongsheng, Jing, Hongyang, Cao, Rangjuan, Kim, Chae, Safar, Jiri G, Xiong, Wen-Cheng, Mei, Lin

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Rapid and ultra-sensitive quantitation of disease-associated α-synuclein seeds in brain and cerebrospinal fluid by αSyn RT-QuIC von Groveman, Bradley R, Orrù, Christina D, Hughson, Andrew G, Raymond, Lynne D, Zanusso, Gianluigi, Ghetti, Bernardino, Campbell, Katrina J, Safar, Jiri, Galasko, Douglas, Caughey, Byron

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Evaluation of a New Criterion for Detecting Prion Disease With Diffusion Magnetic Resonance Imaging von Bizzi, Alberto, Pascuzzo, Riccardo, Blevins, Janis, Grisoli, Marina, Lodi, Raffaele, Moscatelli, Marco E. M, Castelli, Gianmarco, Cohen, Mark L, Schonberger, Lawrence B, Foutz, Aaron, Safar, Jiri G, Appleby, Brian S, Gambetti, Pierluigi

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Structurally distinct external solvent-exposed domains drive replication of major human prions von Siddiqi, Mohammad Khursheed, Kim, Chae, Haldiman, Tracy, Kacirova, Miroslava, Wang, Benlian, Bohon, Jen, Chance, Mark R, Kiselar, Janna, Safar, Jiri G

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Structural attributes of mammalian prion infectivity: Insights from studies with synthetic prions von Li, Qiuye, Wang, Fei, Xiao, Xiangzhu, Kim, Chae, Bohon, Jen, Kiselar, Janna, Safar, Jiri G., Ma, Jiyan, Surewicz, Witold K.

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Rapidly progressive Alzheimer's disease features distinct structures of amyloid-β von Cohen, Mark L, Kim, Chae, Haldiman, Tracy, ElHag, Mohamed, Mehndiratta, Prachi, Pichet, Termsarasab, Lissemore, Frances, Shea, Michelle, Cohen, Yvonne, Chen, Wei, Blevins, Janis, Appleby, Brian S, Surewicz, Krystyna, Surewicz, Witold K, Sajatovic, Martha, Tatsuoka, Curtis, Zhang, Shulin, Mayo, Ping, Butkiewicz, Mariusz, Haines, Jonathan L, Lerner, Alan J, Safar, Jiri G

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Autoantibodies against the prion protein in individuals with PRNP mutations von Frontzek, Karl, Carta, Manfredi, Losa, Marco, Epskamp, Mirka, Meisl, Georg, Anane, Alice, Brandel, Jean-Philippe, Camenisch, Ulrike, Castilla, Joaquín, Haïk, Stéphane, Knowles, Tuomas, Lindner, Ewald, Lutterotti, Andreas, Minikel, Eric Vallabh, Roiter, Ignazio, Safar, Jiri G., Sanchez-Valle, Raquel, Žáková, Dana, Hornemann, Simone, Aguzzi, Adriano

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Detection of prions in matching post-mortem skin and cerebrospinal fluid samples using second-generation real-time quaking-induced conversion assay von Baranová, Soňa, Moško, Tibor, Brůžová, Magdalena, Haldiman, Tracy, Kim, Chae, Safar, Jiri G., Matěj, Radoslav, Holada, Karel

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Pathologic tau conformer ensembles induce dynamic, liquid-liquid phase separation events at the nuclear envelope von Kang, Sang-Gyun, Han, Zhuang Zhuang, Daude, Nathalie, McNamara, Emily, Wohlgemuth, Serene, Molina-Porcel, Laura, Safar, Jiri G, Mok, Sue-Ann, Westaway, David

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Distinct conformers of amyloid beta accumulate in the neocortex of patients with rapidly progressive Alzheimer's disease von Liu, He, Kim, Chae, Haldiman, Tracy, Sigurdson, Christina J., Nyström, Sofie, Nilsson, K. Peter R., Cohen, Mark L., Wisniewski, Thomas, Hammarström, Per, Safar, Jiri G.

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Artificial strain of human prions created in vitro von Kim, Chae, Xiao, Xiangzhu, Chen, Shugui, Haldiman, Tracy, Smirnovas, Vitautas, Kofskey, Diane, Warren, Miriam, Surewicz, Krystyna, Maurer, Nicholas R., Kong, Qingzhong, Surewicz, Witold, Safar, Jiri G.

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Prion protein quantification in human cerebrospinal fluid as a tool for prion disease drug development von Vallabh, Sonia M., Nobuhara, Chloe K., Llorens, Franc, Zerr, Inga, Parchi, Piero, Capellari, Sabina, Kuhn, Eric, Klickstein, Jacob, Safar, Jiri G., Nery, Flavia C., Swoboda, Kathryn J., Geschwind, Michael D., Zetterberg, Henrik, Arnold, Steven E., Minikel, Eric Vallabh, Schreiber, Stuart L.

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Age at onset in genetic prion disease and the design of preventive clinical trials von Minikel, Eric Vallabh, Vallabh, Sonia M, Orseth, Margaret C, Brandel, Jean-Philippe, Haïk, Stéphane, Laplanche, Jean-Louis, Zerr, Inga, Parchi, Piero, Capellari, Sabina, Safar, Jiri, Kenny, Janna, Fong, Jamie C, Takada, Leonel T, Ponto, Claudia, Hermann, Peter, Knipper, Tobias, Stehmann, Christiane, Kitamoto, Tetsuyuki, Ae, Ryusuke, Hamaguchi, Tsuyoshi, Sanjo, Nobuo, Tsukamoto, Tadashi, Mizusawa, Hidehiro, Collins, Steven J, Chiesa, Roberto, Roiter, Ignazio, de Pedro-Cuesta, Jesús, Calero, Miguel, Geschwind, Michael D, Yamada, Masahito, Nakamura, Yosikazu, Mead, Simon

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